Gene name: APC5
Reference locus (S288C): YOR249C
Gene biotype: protein_coding
Description: Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C); APC/C is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition; component of the platform domain of the APC/C, based on structural analysis; relative distribution to nuclear foci decreases upon DNA replication stress; Belongs to the APC5 family
Top 10 interactors (score): CDC26 (0.999); APC2 (0.999); APC1 (0.999); APC4 (0.999); MND2 (0.999); CDC27 (0.999); APC9 (0.999); CDC16 (0.999); APC11 (0.999); SWM1 (0.999); CDC23 (0.999); DOC1 (0.999); SLX8 (0.9); SLX5 (0.9); MET30 (0.9); ASI1 (0.9); ASI2 (0.9); CDC4 (0.9); ASI3 (0.9); CDC20 (0.886)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:789445-791502:- | gene-YOR249C_AKU4011 | rna-NM_001183668.3_AKU4011 | cds-NP_014892.3_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000123.1:191488-193545:- | gene-YOR249C_BG1 | rna-NM_001183668.3_BG1 | cds-NP_014892.3_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:774913-776970:- | gene-YOR249C_Bruggeman | rna-NM_001183668.3_Bruggeman | cds-NP_014892.3_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:775565-777622:- | gene-YOR249C_CAT1 | rna-NM_001183668.3_CAT1 | cds-NP_014892.3_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:772434-774491:- | gene-YOR249C_CBS1585 | rna-NM_001183668.3_CBS1585 | cds-NP_014892.3_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:771130-773187:- | gene-YOR249C_CBS436 | rna-NM_001183668.3_CBS436 | cds-NP_014892.3_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:769553-771610:- | gene-YOR249C_CBS6412 | rna-NM_001183668.3_CBS6412 | cds-NP_014892.3_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:778193-780250:- | gene-YOR249C_CBS6413 | rna-NM_001183668.3_CBS6413 | cds-NP_014892.3_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:798438-800495:- | gene-YOR249C_CENPK1137D | rna-NM_001183668.3_CENPK1137D | cds-NP_014892.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:765562-767619:- | gene-YOR249C_EthanolRed | rna-NM_001183668.3_EthanolRed | cds-NP_014892.3_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:770961-773018:- | gene-YOR249C_FaliES1 | rna-NM_001183668.3_FaliES1 | cds-NP_014892.3_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000381.1:53811-55868:+ | gene-YOR249C_JAY291 | rna-NM_001183668.3_JAY291 | cds-NP_014892.3_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:779185-781242:- | gene-YOR249C_MUCL30387 | rna-NM_001183668.3_MUCL30387 | cds-NP_014892.3_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:786302-788359:- | gene-YOR249C_MUCL30388 | rna-NM_001183668.3_MUCL30388 | cds-NP_014892.3_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:779764-781821:- | gene-YOR249C_MUCL39482 | rna-NM_001183668.3_MUCL39482 | cds-NP_014892.3_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:789354-791411:- | gene-YOR249C_MUCL42920 | rna-NM_001183668.3_MUCL42920 | cds-NP_014892.3_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:798563-800620:- | gene-YOR249C_NCIM3186 | rna-NM_001183668.3_NCIM3186 | cds-NP_014892.3_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:779863-781920:- | gene-YOR249C_NCYC1407 | rna-NM_001183668.3_NCYC1407 | cds-NP_014892.3_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:779168-781225:- | gene-YOR249C_PE2H3 | rna-NM_001183668.3_PE2H3 | cds-NP_014892.3_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:789545-791602:- | gene-YOR249C_PE2H4 | rna-NM_001183668.3_PE2H4 | cds-NP_014892.3_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:798674-800731:- | gene-YOR249C_S288C | rna-NM_001183668.3_S288C | cds-NP_014892.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000006.1:208669-210726:- | gene-YOR249C_SA1 | rna-NM_001183668.3_SA1 | cds-NP_014892.3_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:770144-772201:- | gene-YOR249C_ThermosaccDry | rna-NM_001183668.3_ThermosaccDry | cds-NP_014892.3_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:833608-835665:- | gene-YOR249C_VR1 | rna-NM_001183668.3_VR1 | cds-NP_014892.3_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:503060-505117:- | gene-YOR249C_ZTW1 | rna-NM_001183668.3_ZTW1 | cds-NP_014892.3_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:775924-777984:- | gene-YOR249C_Sparadoxus | rna-NM_001183668.3_Sparadoxus | cds-NP_014892.3_Sparadoxus | 87.6 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |