Gene name: APC4
Reference locus (S288C): YDR118W
Gene biotype: protein_coding
Description: Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C); APC/C is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition; component of the platform domain of the APC/C, based on structural analysis; relative distribution to the nucleus increases upon DNA replication stress
Top 10 interactors (score): SWM1 (0.999); CDC23 (0.999); CDC16 (0.999); CDC26 (0.999); APC5 (0.999); MND2 (0.999); APC9 (0.999); CDC27 (0.999); APC1 (0.999); DOC1 (0.999); APC11 (0.999); APC2 (0.999); MAD2 (0.996); MAD3 (0.994); AMA1 (0.989); CDH1 (0.986); BUB3 (0.985); CDC20 (0.983); BUB1 (0.979); SLX8 (0.903)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:656827-658785:+ | gene-YDR118W_AKU4011 | rna-NM_001180426.3_AKU4011 | cds-NP_010403.3_AKU4011 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:466101-468059:- | gene-YDR118W_BG1 | rna-NM_001180426.3_BG1 | cds-NP_010403.3_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:688887-690845:+ | gene-YDR118W_Bruggeman | rna-NM_001180426.3_Bruggeman | cds-NP_010403.3_Bruggeman | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:675616-677574:+ | gene-YDR118W_CAT1 | rna-NM_001180426.3_CAT1 | cds-NP_010403.3_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:647865-649823:+ | gene-YDR118W_CBS1585 | rna-NM_001180426.3_CBS1585 | cds-NP_010403.3_CBS1585 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:673739-675697:+ | gene-YDR118W_CBS436 | rna-NM_001180426.3_CBS436 | cds-NP_010403.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:644217-646175:+ | gene-YDR118W_CBS6412 | rna-NM_001180426.3_CBS6412 | cds-NP_010403.3_CBS6412 | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:673193-675151:+ | gene-YDR118W_CBS6413 | rna-NM_001180426.3_CBS6413 | cds-NP_010403.3_CBS6413 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:678325-680283:+ | gene-YDR118W_CENPK1137D | rna-NM_001180426.3_CENPK1137D | cds-NP_010403.3_CENPK1137D | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:658594-660552:+ | gene-YDR118W_EthanolRed | rna-NM_001180426.3_EthanolRed | cds-NP_010403.3_EthanolRed | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:665388-667346:+ | gene-YDR118W_FaliES1 | rna-NM_001180426.3_FaliES1 | cds-NP_010403.3_FaliES1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000002.1:17497-19455:+ | gene-YDR118W_JAY291 | rna-NM_001180426.3_JAY291 | cds-NP_010403.3_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:674812-676770:+ | gene-YDR118W_MUCL30387 | rna-NM_001180426.3_MUCL30387 | cds-NP_010403.3_MUCL30387 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:663830-665788:+ | gene-YDR118W_MUCL30388 | rna-NM_001180426.3_MUCL30388 | cds-NP_010403.3_MUCL30388 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:649206-651164:+ | gene-YDR118W_MUCL39482 | rna-NM_001180426.3_MUCL39482 | cds-NP_010403.3_MUCL39482 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:587172-589130:+ | gene-YDR118W_MUCL42920 | rna-NM_001180426.3_MUCL42920 | cds-NP_010403.3_MUCL42920 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:685805-687763:+ | gene-YDR118W_NCIM3186 | rna-NM_001180426.3_NCIM3186 | cds-NP_010403.3_NCIM3186 | 96.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:648611-650569:+ | gene-YDR118W_NCYC1407 | rna-NM_001180426.3_NCYC1407 | cds-NP_010403.3_NCYC1407 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:667928-669886:+ | gene-YDR118W_PE2H3 | rna-NM_001180426.3_PE2H3 | cds-NP_010403.3_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:667233-669191:+ | gene-YDR118W_PE2H4 | rna-NM_001180426.3_PE2H4 | cds-NP_010403.3_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:685882-687840:+ | gene-YDR118W_S288C | rna-NM_001180426.3_S288C | cds-NP_010403.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000009.1:34544-36502:+ | gene-YDR118W_SA1 | rna-NM_001180426.3_SA1 | cds-NP_010403.3_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:664910-666868:+ | gene-YDR118W_ThermosaccDry | rna-NM_001180426.3_ThermosaccDry | cds-NP_010403.3_ThermosaccDry | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:678238-680196:+ | gene-YDR118W_VR1 | rna-NM_001180426.3_VR1 | cds-NP_010403.3_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:662499-664457:+ | gene-YDR118W_ZTW1 | rna-NM_001180426.3_ZTW1 | cds-NP_010403.3_ZTW1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:666911-668869:+ | gene-YDR118W_Sparadoxus | rna-NM_001180426.3_Sparadoxus | cds-NP_010403.3_Sparadoxus | 87.0 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |