Gene name: APC2
Reference locus (S288C): YLR127C
Gene biotype: protein_coding
Description: Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C); which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition; component of the catalytic core of the APC/C; has similarity to cullin Cdc53p
Top 10 interactors (score): DOC1 (0.999); APC11 (0.999); SWM1 (0.999); CDC23 (0.999); APC9 (0.999); CDC27 (0.999); MND2 (0.999); APC4 (0.999); APC1 (0.999); CDC26 (0.999); CDC16 (0.999); APC5 (0.999); CDC20 (0.998); CDH1 (0.998); AMA1 (0.994); MAD2 (0.99); UBC11 (0.986); HRT1 (0.955); MAD3 (0.914); MET30 (0.901)
Homologues (species, bitscore): ANAPC2 (Homo sapiens, 119.8); Anapc2 (Mus musculus, 109.4); anapc2 (Danio rerio, 105.5); anapc2 (Xenopus tropicalis, 119.8); mr (Drosophila melanogaster, 109.8); apc-2 (Caenorhabditis elegans, 57.0); At2g04660 (Arabidopsis thaliana, 129.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:378239-380800:- | gene-YLR127C_AKU4011 | rna-NM_001182014.1_AKU4011 | cds-NP_013228.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000212.1:342024-344584:- | gene-YLR127C_BG1 | rna-NM_001182014.1_BG1 | cds-NP_013228.1_BG1 | 99.7 | 99.9 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:390118-392679:- | gene-YLR127C_Bruggeman | rna-NM_001182014.1_Bruggeman | cds-NP_013228.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:389534-392094:- | gene-YLR127C_CAT1 | rna-NM_001182014.1_CAT1 | cds-NP_013228.1_CAT1 | 99.4 | 99.9 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:385383-387944:- | gene-YLR127C_CBS1585 | rna-NM_001182014.1_CBS1585 | cds-NP_013228.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:375623-378184:- | gene-YLR127C_CBS436 | rna-NM_001182014.1_CBS436 | cds-NP_013228.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:383800-386361:- | gene-YLR127C_CBS6412 | rna-NM_001182014.1_CBS6412 | cds-NP_013228.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:385648-388209:- | gene-YLR127C_CBS6413 | rna-NM_001182014.1_CBS6413 | cds-NP_013228.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:380780-383341:- | gene-YLR127C_CENPK1137D | rna-NM_001182014.1_CENPK1137D | cds-NP_013228.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:378440-381001:- | gene-YLR127C_EthanolRed | rna-NM_001182014.1_EthanolRed | cds-NP_013228.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:377951-380512:- | gene-YLR127C_FaliES1 | rna-NM_001182014.1_FaliES1 | cds-NP_013228.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000117.1:12677-15237:+ | gene-YLR127C_JAY291 | rna-NM_001182014.1_JAY291 | cds-NP_013228.1_JAY291 | 99.6 | 99.9 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:390109-392670:- | gene-YLR127C_MUCL30387 | rna-NM_001182014.1_MUCL30387 | cds-NP_013228.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:394928-397489:- | gene-YLR127C_MUCL30388 | rna-NM_001182014.1_MUCL30388 | cds-NP_013228.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:385892-388453:- | gene-YLR127C_MUCL39482 | rna-NM_001182014.1_MUCL39482 | cds-NP_013228.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:386017-388578:- | gene-YLR127C_MUCL42920 | rna-NM_001182014.1_MUCL42920 | cds-NP_013228.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:395732-398293:- | gene-YLR127C_NCIM3186 | rna-NM_001182014.1_NCIM3186 | cds-NP_013228.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:378164-380725:- | gene-YLR127C_NCYC1407 | rna-NM_001182014.1_NCYC1407 | cds-NP_013228.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:383734-386294:- | gene-YLR127C_PE2H3 | rna-NM_001182014.1_PE2H3 | cds-NP_013228.1_PE2H3 | 99.7 | 99.9 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:383475-386035:- | gene-YLR127C_PE2H4 | rna-NM_001182014.1_PE2H4 | cds-NP_013228.1_PE2H4 | 99.7 | 99.9 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:395758-398319:- | gene-YLR127C_S288C | rna-NM_001182014.1_S288C | cds-NP_013228.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000055.1:21671-24232:- | gene-YLR127C_SA1 | rna-NM_001182014.1_SA1 | cds-NP_013228.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:379161-381722:- | gene-YLR127C_ThermosaccDry | rna-NM_001182014.1_ThermosaccDry | cds-NP_013228.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:391876-394436:- | gene-YLR127C_VR1 | rna-NM_001182014.1_VR1 | cds-NP_013228.1_VR1 | 99.5 | 99.9 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000023.1:376958-379519:- | gene-YLR127C_ZTW1 | rna-NM_001182014.1_ZTW1 | cds-NP_013228.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:387044-389605:- | gene-YLR127C_Sparadoxus | rna-NM_001182014.1_Sparadoxus | cds-NP_013228.1_Sparadoxus | 88.9 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |