Gene name: APC11
Reference locus (S288C): YDL008W
Gene biotype: protein_coding
Description: Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C); which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition; contains a RING-H2 domain that is required for activity
Top 10 interactors (score): CDC26 (0.999); CDC27 (0.999); APC1 (0.999); UBC11 (0.999); APC2 (0.999); APC9 (0.999); CDC23 (0.999); UBC4 (0.999); SWM1 (0.999); CDC16 (0.999); APC5 (0.999); APC4 (0.999); DOC1 (0.999); CDC20 (0.998); CDH1 (0.997); HRT1 (0.997); MND2 (0.996); UBC1 (0.996); UBC5 (0.992); AMA1 (0.99)
Homologues (species, bitscore): Anapc11 (Mus musculus, 88.6); anapc11 (Danio rerio, 97.8); lmgA (Drosophila melanogaster, 86.3); apc-11 (Caenorhabditis elegans, 84.7); APC11 (Arabidopsis thaliana, 93.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:419579-420076:+ | gene-YDL008W_AKU4011 | rna-NM_001180067.3_AKU4011 | cds-NP_010276.3_AKU4011 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000102.1:129809-130306:- | gene-YDL008W_BG1 | rna-NM_001180067.3_BG1 | cds-NP_010276.3_BG1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:440148-440645:+ | gene-YDL008W_Bruggeman | rna-NM_001180067.3_Bruggeman | cds-NP_010276.3_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:433044-433541:+ | gene-YDL008W_CAT1 | rna-NM_001180067.3_CAT1 | cds-NP_010276.3_CAT1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:415993-416490:+ | gene-YDL008W_CBS1585 | rna-NM_001180067.3_CBS1585 | cds-NP_010276.3_CBS1585 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:433520-434017:+ | gene-YDL008W_CBS436 | rna-NM_001180067.3_CBS436 | cds-NP_010276.3_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:413707-414204:+ | gene-YDL008W_CBS6412 | rna-NM_001180067.3_CBS6412 | cds-NP_010276.3_CBS6412 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:435759-436256:+ | gene-YDL008W_CBS6413 | rna-NM_001180067.3_CBS6413 | cds-NP_010276.3_CBS6413 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:432359-432856:+ | gene-YDL008W_CENPK1137D | rna-NM_001180067.3_CENPK1137D | cds-NP_010276.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:428412-428909:+ | gene-YDL008W_EthanolRed | rna-NM_001180067.3_EthanolRed | cds-NP_010276.3_EthanolRed | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:434604-435101:+ | gene-YDL008W_FaliES1 | rna-NM_001180067.3_FaliES1 | cds-NP_010276.3_FaliES1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000370.1:49090-49587:+ | gene-YDL008W_JAY291 | rna-NM_001180067.3_JAY291 | cds-NP_010276.3_JAY291 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:434038-434535:+ | gene-YDL008W_MUCL30387 | rna-NM_001180067.3_MUCL30387 | cds-NP_010276.3_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:424494-424991:+ | gene-YDL008W_MUCL30388 | rna-NM_001180067.3_MUCL30388 | cds-NP_010276.3_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:417667-418164:+ | gene-YDL008W_MUCL39482 | rna-NM_001180067.3_MUCL39482 | cds-NP_010276.3_MUCL39482 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:339546-340043:+ | gene-YDL008W_MUCL42920 | rna-NM_001180067.3_MUCL42920 | cds-NP_010276.3_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:433420-433917:+ | gene-YDL008W_NCIM3186 | rna-NM_001180067.3_NCIM3186 | cds-NP_010276.3_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:417088-417585:+ | gene-YDL008W_NCYC1407 | rna-NM_001180067.3_NCYC1407 | cds-NP_010276.3_NCYC1407 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:424571-425068:+ | gene-YDL008W_PE2H3 | rna-NM_001180067.3_PE2H3 | cds-NP_010276.3_PE2H3 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:423930-424427:+ | gene-YDL008W_PE2H4 | rna-NM_001180067.3_PE2H4 | cds-NP_010276.3_PE2H4 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:433497-433994:+ | gene-YDL008W_S288C | rna-NM_001180067.3_S288C | cds-NP_010276.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000010.1:973-1470:- | gene-YDL008W_SA1 | rna-NM_001180067.3_SA1 | cds-NP_010276.3_SA1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:434064-434561:+ | gene-YDL008W_ThermosaccDry | rna-NM_001180067.3_ThermosaccDry | cds-NP_010276.3_ThermosaccDry | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:437077-437574:+ | gene-YDL008W_VR1 | rna-NM_001180067.3_VR1 | cds-NP_010276.3_VR1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:431962-432459:+ | gene-YDL008W_ZTW1 | rna-NM_001180067.3_ZTW1 | cds-NP_010276.3_ZTW1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:436079-436576:+ | gene-YDL008W_Sparadoxus | rna-NM_001180067.3_Sparadoxus | cds-NP_010276.3_Sparadoxus | 91.1 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |