Gene name: APA1
Reference locus (S288C): YCL050C
Gene biotype: protein_coding
Description: Protein APA1; AP4A phosphorylase; bifunctional diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase and ADP sulfurylase involved in catabolism of bis(5'-nucleosidyl) tetraphosphates; catalyzes phosphorolysis of dinucleoside oligophosphates, cleaving substrates' alpha/beta-anhydride bond and introducing Pi into the beta-position of the corresponding NDP formed; protein abundance increases under DNA replication stress; APA1 has a paralog, APA2, that arose from the whole genome duplication; Belongs to the ATP adenylyltransferase family
Top 10 interactors (score): MET3 (0.976); APA2 (0.974); MET14 (0.9); MET22 (0.9); HNT2 (0.9); IPP1 (0.813); MRC1 (0.711); GEX1 (0.595); GIT1 (0.574); RPN11 (0.463); DLD3 (0.455); FUR1 (0.414); YDR341C (0.404); ADE3 (0.403); TOM1 (0.403)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005297.1:39118-40083:- | gene-YCL050C_AKU4011 | rna-NM_001178695.1_AKU4011 | cds-NP_009880.2_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000086.1:5743-6708:+ | gene-YCL050C_BG1 | rna-NM_001178695.1_BG1 | cds-NP_009880.2_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005505.1:26984-27949:- | gene-YCL050C_Bruggeman | rna-NM_001178695.1_Bruggeman | cds-NP_009880.2_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005521.1:38989-39954:- | gene-YCL050C_CAT1 | rna-NM_001178695.1_CAT1 | cds-NP_009880.2_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005361.1:39801-40766:- | gene-YCL050C_CBS1585 | rna-NM_001178695.1_CBS1585 | cds-NP_009880.2_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005345.1:38359-39324:- | gene-YCL050C_CBS436 | rna-NM_001178695.1_CBS436 | cds-NP_009880.2_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005329.1:27599-28564:- | gene-YCL050C_CBS6412 | rna-NM_001178695.1_CBS6412 | cds-NP_009880.2_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005313.1:38606-39571:- | gene-YCL050C_CBS6413 | rna-NM_001178695.1_CBS6413 | cds-NP_009880.2_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001524.1:37410-38375:- | gene-YCL050C_CENPK1137D | rna-NM_001178695.1_CENPK1137D | cds-NP_009880.2_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005473.1:37351-38316:- | gene-YCL050C_EthanolRed | rna-NM_001178695.1_EthanolRed | cds-NP_009880.2_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005537.1:38114-39079:- | gene-YCL050C_FaliES1 | rna-NM_001178695.1_FaliES1 | cds-NP_009880.2_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000225.1:45259-46224:+ | gene-YCL050C_JAY291 | rna-NM_001178695.1_JAY291 | cds-NP_009880.2_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005409.1:25588-26553:- | gene-YCL050C_MUCL30387 | rna-NM_001178695.1_MUCL30387 | cds-NP_009880.2_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005441.1:25846-26811:- | gene-YCL050C_MUCL30388 | rna-NM_001178695.1_MUCL30388 | cds-NP_009880.2_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005281.1:40188-41153:- | gene-YCL050C_MUCL39482 | rna-NM_001178695.1_MUCL39482 | cds-NP_009880.2_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005425.1:26378-27343:- | gene-YCL050C_MUCL42920 | rna-NM_001178695.1_MUCL42920 | cds-NP_009880.2_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011812.1:37468-38433:- | gene-YCL050C_NCIM3186 | rna-NM_001178695.1_NCIM3186 | cds-NP_009880.2_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005265.1:40510-41475:- | gene-YCL050C_NCYC1407 | rna-NM_001178695.1_NCYC1407 | cds-NP_009880.2_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994142.1:38283-39248:- | gene-YCL050C_PE2H3 | rna-NM_001178695.1_PE2H3 | cds-NP_009880.2_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999874.1:38240-39205:- | gene-YCL050C_PE2H4 | rna-NM_001178695.1_PE2H4 | cds-NP_009880.2_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001135.5:37836-38801:- | gene-YCL050C_S288C | rna-NM_001178695.1_S288C | cds-NP_009880.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000061.1:24963-25928:- | gene-YCL050C_SA1 | rna-NM_001178695.1_SA1 | cds-NP_009880.2_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005489.1:38432-39397:- | gene-YCL050C_ThermosaccDry | rna-NM_001178695.1_ThermosaccDry | cds-NP_009880.2_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005457.1:44767-45732:- | gene-YCL050C_VR1 | rna-NM_001178695.1_VR1 | cds-NP_009880.2_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000004.1:38658-39622:- | gene-YCL050C_ZTW1 | rna-NM_001178695.1_ZTW1 | cds-NP_009880.2_ZTW1 | 99.3 | 99.8 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047489.1:68311-69276:- | gene-YCL050C_Sparadoxus | rna-NM_001178695.1_Sparadoxus | cds-NP_009880.2_Sparadoxus | 93.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |