ANB1 (YJR047C)


Gene profile

Gene name: ANB1
Reference locus (S288C): YJR047C
Gene biotype: protein_coding

Description: Eukaryotic translation initiation factor 5A-2; Translation elongation factor eIF-5A; previously thought to function in translation initiation; undergoes an essential hypusination modification; expressed under anaerobic conditions; ANB1 has a paralog, HYP2, that arose from the whole genome duplication; human EIF5A complements the inviability of the yeast hyp2 anb1 double null mutant

Top 10 interactors (score): DYS1 (0.999); LIA1 (0.995); TEF4 (0.974); RPL5 (0.971); CAM1 (0.953); RPS2 (0.951); RPL10 (0.949); HEM13 (0.947); RPS13 (0.943); ASC1 (0.937); RPL28 (0.932); RPS20 (0.931); RPL39 (0.923); RPL15B (0.913); RPL15A (0.912); RPL38 (0.912); DAN1 (0.911); RPS3 (0.909); ROX1 (0.905); EFT1 (0.902)

Homologues (species, bitscore): EIF5A2 (Homo sapiens, 214.5); Eif5a2 (Mus musculus, 214.5); eif5a (Danio rerio, 215.3); eif5a (Xenopus tropicalis, 206.1); eIF-5A (Drosophila melanogaster, 204.1); iff-2 (Caenorhabditis elegans, 192.2); ELF5A-1 (Arabidopsis thaliana, 200.7)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005304.1:496598-497071:- gene-YJR047C_AKU4011 rna-NM_001181705.3_AKU4011 cds-NP_012581.3_AKU4011 100.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000190.1:115868-116341:+ gene-YJR047C_BG1 rna-NM_001181705.3_BG1 cds-NP_012581.3_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005512.1:510649-511122:- gene-YJR047C_Bruggeman rna-NM_001181705.3_Bruggeman cds-NP_012581.3_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005528.1:514811-515284:- gene-YJR047C_CAT1 rna-NM_001181705.3_CAT1 cds-NP_012581.3_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005368.1:508666-509139:- gene-YJR047C_CBS1585 rna-NM_001181705.3_CBS1585 cds-NP_012581.3_CBS1585 100.0 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005352.1:527124-527597:- gene-YJR047C_CBS436 rna-NM_001181705.3_CBS436 cds-NP_012581.3_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005336.1:496383-496856:- gene-YJR047C_CBS6412 rna-NM_001181705.3_CBS6412 cds-NP_012581.3_CBS6412 99.7 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005320.1:498628-499101:- gene-YJR047C_CBS6413 rna-NM_001181705.3_CBS6413 cds-NP_012581.3_CBS6413 100.0 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001531.1:507258-507731:- gene-YJR047C_CENPK1137D rna-NM_001181705.3_CENPK1137D cds-NP_012581.3_CENPK1137D 99.7 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005480.1:501513-501986:- gene-YJR047C_EthanolRed rna-NM_001181705.3_EthanolRed cds-NP_012581.3_EthanolRed 100.0 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005544.1:512730-513203:- gene-YJR047C_FaliES1 rna-NM_001181705.3_FaliES1 cds-NP_012581.3_FaliES1 100.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000250.1:27593-27873:- gene-YJR047C_JAY291 rna-NM_001181705.3_JAY291 cds-NP_012581.3_JAY291 59.2 59.2 Verified 1 1 0 False False True False False
MUCL30387 GCA_001738515.1 Bread Europe CM005416.1:510939-511412:- gene-YJR047C_MUCL30387 rna-NM_001181705.3_MUCL30387 cds-NP_012581.3_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005448.1:507491-507964:- gene-YJR047C_MUCL30388 rna-NM_001181705.3_MUCL30388 cds-NP_012581.3_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005288.1:502125-502598:- gene-YJR047C_MUCL39482 rna-NM_001181705.3_MUCL39482 cds-NP_012581.3_MUCL39482 100.0 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005432.1:506898-507371:- gene-YJR047C_MUCL42920 rna-NM_001181705.3_MUCL42920 cds-NP_012581.3_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011819.1:524887-525360:- gene-YJR047C_NCIM3186 rna-NM_001181705.3_NCIM3186 cds-NP_012581.3_NCIM3186 99.7 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005272.1:499969-500442:- gene-YJR047C_NCYC1407 rna-NM_001181705.3_NCYC1407 cds-NP_012581.3_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994149.1:517830-518303:- gene-YJR047C_PE2H3 rna-NM_001181705.3_PE2H3 cds-NP_012581.3_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999881.1:511526-511999:- gene-YJR047C_PE2H4 rna-NM_001181705.3_PE2H4 cds-NP_012581.3_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001142.9:524908-525381:- gene-YJR047C_S288C rna-NM_001181705.3_S288C cds-NP_012581.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000003.1:309756-310229:- gene-YJR047C_SA1 rna-NM_001181705.3_SA1 cds-NP_012581.3_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005496.1:506418-506891:- gene-YJR047C_ThermosaccDry rna-NM_001181705.3_ThermosaccDry cds-NP_012581.3_ThermosaccDry 100.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005464.1:508909-509382:- gene-YJR047C_VR1 rna-NM_001181705.3_VR1 cds-NP_012581.3_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000021.1:486306-486779:- gene-YJR047C_ZTW1 rna-NM_001181705.3_ZTW1 cds-NP_012581.3_ZTW1 99.7 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047496.1:512668-513141:- gene-YJR047C_Sparadoxus rna-NM_001181705.3_Sparadoxus cds-NP_012581.3_Sparadoxus 96.4 100.0 Verified 1 1 1 False True False False False

Additional files