Gene name: AME1
Reference locus (S288C): YBR211C
Gene biotype: protein_coding
Description: Central kinetochore subunit AME1; Essential kinetochore protein associated with microtubules and SPBs; component of the kinetochore sub-complex COMA (Ctf19p, Okp1p, Mcm21p, Ame1p); involved in spindle checkpoint maintenance; orthologous to human centromere constitutive-associated network (CCAN) subunit CENP-U and fission yeast Mis17; relative distribution to the nucleus increases upon DNA replication stress
Top 10 interactors (score): MCM21 (0.999); OKP1 (0.999); CTF19 (0.999); CSE4 (0.995); IML3 (0.994); NKP1 (0.994); MCM16 (0.989); CTF3 (0.989); MTW1 (0.987); CHL4 (0.987); MCM22 (0.987); NKP2 (0.986); DSN1 (0.983); NSL1 (0.979); NNF1 (0.97); HHF1 (0.942); MIF2 (0.935); HTA1 (0.923); SPC24 (0.916); CNN1 (0.909)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:630445-631419:- | gene-YBR211C_AKU4011 | rna-NM_001178559.3_AKU4011 | cds-NP_009770.3_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000066.1:1383-2357:- | gene-YBR211C_BG1 | rna-NM_001178559.3_BG1 | cds-NP_009770.3_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:631629-632603:- | gene-YBR211C_Bruggeman | rna-NM_001178559.3_Bruggeman | cds-NP_009770.3_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:634833-635807:- | gene-YBR211C_CAT1 | rna-NM_001178559.3_CAT1 | cds-NP_009770.3_CAT1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:621977-622951:- | gene-YBR211C_CBS1585 | rna-NM_001178559.3_CBS1585 | cds-NP_009770.3_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:628432-629406:- | gene-YBR211C_CBS436 | rna-NM_001178559.3_CBS436 | cds-NP_009770.3_CBS436 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:716954-717928:- | gene-YBR211C_CBS6412 | rna-NM_001178559.3_CBS6412 | cds-NP_009770.3_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:628016-628990:- | gene-YBR211C_CBS6413 | rna-NM_001178559.3_CBS6413 | cds-NP_009770.3_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:639915-640889:- | gene-YBR211C_CENPK1137D | rna-NM_001178559.3_CENPK1137D | cds-NP_009770.3_CENPK1137D | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:753701-754675:- | gene-YBR211C_EthanolRed | rna-NM_001178559.3_EthanolRed | cds-NP_009770.3_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:646808-647782:- | gene-YBR211C_FaliES1 | rna-NM_001178559.3_FaliES1 | cds-NP_009770.3_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000326.1:1187-2161:- | gene-YBR211C_JAY291 | rna-NM_001178559.3_JAY291 | cds-NP_009770.3_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:633642-634616:- | gene-YBR211C_MUCL30387 | rna-NM_001178559.3_MUCL30387 | cds-NP_009770.3_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:650720-651694:- | gene-YBR211C_MUCL30388 | rna-NM_001178559.3_MUCL30388 | cds-NP_009770.3_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:620329-621303:- | gene-YBR211C_MUCL39482 | rna-NM_001178559.3_MUCL39482 | cds-NP_009770.3_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:629835-630809:- | gene-YBR211C_MUCL42920 | rna-NM_001178559.3_MUCL42920 | cds-NP_009770.3_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:645955-646929:- | gene-YBR211C_NCIM3186 | rna-NM_001178559.3_NCIM3186 | cds-NP_009770.3_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:622192-623166:- | gene-YBR211C_NCYC1407 | rna-NM_001178559.3_NCYC1407 | cds-NP_009770.3_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:645325-646299:- | gene-YBR211C_PE2H3 | rna-NM_001178559.3_PE2H3 | cds-NP_009770.3_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:643001-643975:- | gene-YBR211C_PE2H4 | rna-NM_001178559.3_PE2H4 | cds-NP_009770.3_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:646158-647132:- | gene-YBR211C_S288C | rna-NM_001178559.3_S288C | cds-NP_009770.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000019.1:1280-2254:- | gene-YBR211C_SA1 | rna-NM_001178559.3_SA1 | cds-NP_009770.3_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:645818-646792:- | gene-YBR211C_ThermosaccDry | rna-NM_001178559.3_ThermosaccDry | cds-NP_009770.3_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:626005-626979:- | gene-YBR211C_VR1 | rna-NM_001178559.3_VR1 | cds-NP_009770.3_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:618684-619658:- | gene-YBR211C_ZTW1 | rna-NM_001178559.3_ZTW1 | cds-NP_009770.3_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:662633-663595:- | gene-YBR211C_Sparadoxus | rna-NM_001178559.3_Sparadoxus | cds-NP_009770.3_Sparadoxus | 88.0 | 98.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |