AME1 (YBR211C)


Gene profile

Gene name: AME1
Reference locus (S288C): YBR211C
Gene biotype: protein_coding

Description: Central kinetochore subunit AME1; Essential kinetochore protein associated with microtubules and SPBs; component of the kinetochore sub-complex COMA (Ctf19p, Okp1p, Mcm21p, Ame1p); involved in spindle checkpoint maintenance; orthologous to human centromere constitutive-associated network (CCAN) subunit CENP-U and fission yeast Mis17; relative distribution to the nucleus increases upon DNA replication stress

Top 10 interactors (score): MCM21 (0.999); OKP1 (0.999); CTF19 (0.999); CSE4 (0.995); IML3 (0.994); NKP1 (0.994); MCM16 (0.989); CTF3 (0.989); MTW1 (0.987); CHL4 (0.987); MCM22 (0.987); NKP2 (0.986); DSN1 (0.983); NSL1 (0.979); NNF1 (0.97); HHF1 (0.942); MIF2 (0.935); HTA1 (0.923); SPC24 (0.916); CNN1 (0.909)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005296.1:630445-631419:- gene-YBR211C_AKU4011 rna-NM_001178559.3_AKU4011 cds-NP_009770.3_AKU4011 99.7 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000066.1:1383-2357:- gene-YBR211C_BG1 rna-NM_001178559.3_BG1 cds-NP_009770.3_BG1 99.7 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005504.1:631629-632603:- gene-YBR211C_Bruggeman rna-NM_001178559.3_Bruggeman cds-NP_009770.3_Bruggeman 99.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005520.1:634833-635807:- gene-YBR211C_CAT1 rna-NM_001178559.3_CAT1 cds-NP_009770.3_CAT1 99.3 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005360.1:621977-622951:- gene-YBR211C_CBS1585 rna-NM_001178559.3_CBS1585 cds-NP_009770.3_CBS1585 99.7 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005344.1:628432-629406:- gene-YBR211C_CBS436 rna-NM_001178559.3_CBS436 cds-NP_009770.3_CBS436 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005328.1:716954-717928:- gene-YBR211C_CBS6412 rna-NM_001178559.3_CBS6412 cds-NP_009770.3_CBS6412 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005312.1:628016-628990:- gene-YBR211C_CBS6413 rna-NM_001178559.3_CBS6413 cds-NP_009770.3_CBS6413 99.7 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001523.1:639915-640889:- gene-YBR211C_CENPK1137D rna-NM_001178559.3_CENPK1137D cds-NP_009770.3_CENPK1137D 99.4 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005472.1:753701-754675:- gene-YBR211C_EthanolRed rna-NM_001178559.3_EthanolRed cds-NP_009770.3_EthanolRed 99.8 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005536.1:646808-647782:- gene-YBR211C_FaliES1 rna-NM_001178559.3_FaliES1 cds-NP_009770.3_FaliES1 99.8 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000326.1:1187-2161:- gene-YBR211C_JAY291 rna-NM_001178559.3_JAY291 cds-NP_009770.3_JAY291 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005408.1:633642-634616:- gene-YBR211C_MUCL30387 rna-NM_001178559.3_MUCL30387 cds-NP_009770.3_MUCL30387 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005440.1:650720-651694:- gene-YBR211C_MUCL30388 rna-NM_001178559.3_MUCL30388 cds-NP_009770.3_MUCL30388 99.4 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005280.1:620329-621303:- gene-YBR211C_MUCL39482 rna-NM_001178559.3_MUCL39482 cds-NP_009770.3_MUCL39482 99.7 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005424.1:629835-630809:- gene-YBR211C_MUCL42920 rna-NM_001178559.3_MUCL42920 cds-NP_009770.3_MUCL42920 99.6 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011811.1:645955-646929:- gene-YBR211C_NCIM3186 rna-NM_001178559.3_NCIM3186 cds-NP_009770.3_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005264.1:622192-623166:- gene-YBR211C_NCYC1407 rna-NM_001178559.3_NCYC1407 cds-NP_009770.3_NCYC1407 99.7 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994141.1:645325-646299:- gene-YBR211C_PE2H3 rna-NM_001178559.3_PE2H3 cds-NP_009770.3_PE2H3 99.7 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999873.1:643001-643975:- gene-YBR211C_PE2H4 rna-NM_001178559.3_PE2H4 cds-NP_009770.3_PE2H4 99.7 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001134.8:646158-647132:- gene-YBR211C_S288C rna-NM_001178559.3_S288C cds-NP_009770.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000019.1:1280-2254:- gene-YBR211C_SA1 rna-NM_001178559.3_SA1 cds-NP_009770.3_SA1 99.7 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005488.1:645818-646792:- gene-YBR211C_ThermosaccDry rna-NM_001178559.3_ThermosaccDry cds-NP_009770.3_ThermosaccDry 99.8 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005456.1:626005-626979:- gene-YBR211C_VR1 rna-NM_001178559.3_VR1 cds-NP_009770.3_VR1 99.3 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000003.1:618684-619658:- gene-YBR211C_ZTW1 rna-NM_001178559.3_ZTW1 cds-NP_009770.3_ZTW1 99.6 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047488.1:662633-663595:- gene-YBR211C_Sparadoxus rna-NM_001178559.3_Sparadoxus cds-NP_009770.3_Sparadoxus 88.0 98.7 Verified 1 1 1 False True False False False

Additional files