AMA1 (YGR225W)


Gene profile

Gene name: AMA1
Reference locus (S288C): YGR225W
Gene biotype: protein_coding

Description: Meiosis-specific APC/C activator protein AMA1; Activator of meiotic anaphase promoting complex (APC/C); Cdc20p family member; required for initiation of spore wall assembly; required for Clb1p degradation during meiosis; prevents premature assembly of the meiosis I spindle, required for DSB induced prophase I arrest; Belongs to the WD repeat CDC20/Fizzy family

Top 10 interactors (score): CDC16 (0.998); CDC27 (0.997); APC2 (0.994); APC1 (0.991); APC11 (0.99); APC4 (0.989); CDC23 (0.985); DOC1 (0.984); MND2 (0.978); MAD2 (0.975); CDC28 (0.963); CLB1 (0.953); MER1 (0.949); UBC11 (0.944); CDC5 (0.942); MAD3 (0.937); APC9 (0.931); PCH2 (0.929); BUB1 (0.925); ESP1 (0.92)

Homologues (species, bitscore): FZR1 (Homo sapiens, 170.2); Fzr1 (Mus musculus, 170.6); fzr1 (Danio rerio, 170.6); fzr1 (Xenopus tropicalis, 171.4); fzr2 (Drosophila melanogaster, 164.5); fzr-1 (Caenorhabditis elegans, 164.5); CCS52A2 (Arabidopsis thaliana, 156.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005301.1:910447-912321:+ gene-YGR225W_AKU4011 rna-NM_001181354.3_AKU4011 cds-NP_011741.5_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000021.1:190673-192547:+ gene-YGR225W_BG1 rna-NM_001181354.3_BG1 cds-NP_011741.5_BG1 99.4 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005509.1:918151-920025:+ gene-YGR225W_Bruggeman rna-NM_001181354.3_Bruggeman cds-NP_011741.5_Bruggeman 99.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005525.1:916401-918275:+ gene-YGR225W_CAT1 rna-NM_001181354.3_CAT1 cds-NP_011741.5_CAT1 99.4 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005365.1:913397-915271:+ gene-YGR225W_CBS1585 rna-NM_001181354.3_CBS1585 cds-NP_011741.5_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005349.1:917079-918953:+ gene-YGR225W_CBS436 rna-NM_001181354.3_CBS436 cds-NP_011741.5_CBS436 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005333.1:904267-906141:+ gene-YGR225W_CBS6412 rna-NM_001181354.3_CBS6412 cds-NP_011741.5_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005317.1:910326-912200:+ gene-YGR225W_CBS6413 rna-NM_001181354.3_CBS6413 cds-NP_011741.5_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001528.1:944727-946601:+ gene-YGR225W_CENPK1137D rna-NM_001181354.3_CENPK1137D cds-NP_011741.5_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005477.1:898777-900651:+ gene-YGR225W_EthanolRed rna-NM_001181354.3_EthanolRed cds-NP_011741.5_EthanolRed 99.5 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005541.1:903168-905042:+ gene-YGR225W_FaliES1 rna-NM_001181354.3_FaliES1 cds-NP_011741.5_FaliES1 99.5 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000076.1:125222-127096:- gene-YGR225W_JAY291 rna-NM_001181354.3_JAY291 cds-NP_011741.5_JAY291 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005413.1:916066-917940:+ gene-YGR225W_MUCL30387 rna-NM_001181354.3_MUCL30387 cds-NP_011741.5_MUCL30387 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005445.1:915322-917196:+ gene-YGR225W_MUCL30388 rna-NM_001181354.3_MUCL30388 cds-NP_011741.5_MUCL30388 99.4 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005285.1:908474-910348:+ gene-YGR225W_MUCL39482 rna-NM_001181354.3_MUCL39482 cds-NP_011741.5_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005429.1:927026-928900:+ gene-YGR225W_MUCL42920 rna-NM_001181354.3_MUCL42920 cds-NP_011741.5_MUCL42920 99.6 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011816.1:945145-947019:+ gene-YGR225W_NCIM3186 rna-NM_001181354.3_NCIM3186 cds-NP_011741.5_NCIM3186 91.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005269.1:904126-906000:+ gene-YGR225W_NCYC1407 rna-NM_001181354.3_NCYC1407 cds-NP_011741.5_NCYC1407 99.4 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994146.1:929069-930943:+ gene-YGR225W_PE2H3 rna-NM_001181354.3_PE2H3 cds-NP_011741.5_PE2H3 99.5 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999878.1:934175-936049:+ gene-YGR225W_PE2H4 rna-NM_001181354.3_PE2H4 cds-NP_011741.5_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001139.9:945145-947019:+ gene-YGR225W_S288C rna-NM_001181354.3_S288C cds-NP_011741.5_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000045.1:54743-56617:- gene-YGR225W_SA1 rna-NM_001181354.3_SA1 cds-NP_011741.5_SA1 99.4 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005493.1:923679-925553:+ gene-YGR225W_ThermosaccDry rna-NM_001181354.3_ThermosaccDry cds-NP_011741.5_ThermosaccDry 99.5 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005461.1:1028496-1030370:+ gene-YGR225W_VR1 rna-NM_001181354.3_VR1 cds-NP_011741.5_VR1 99.6 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000016.1:225115-226989:+ gene-YGR225W_ZTW1 rna-NM_001181354.3_ZTW1 cds-NP_011741.5_ZTW1 99.4 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047493.1:915862-917737:+ gene-YGR225W_Sparadoxus rna-NM_001181354.3_Sparadoxus cds-NP_011741.5_Sparadoxus 91.0 100.0 Verified 1 1 1 False True False False False

Additional files