Gene name: ALY1
Reference locus (S288C): YKR021W
Gene biotype: protein_coding
Description: Arrestin-related trafficking adapter 6; Alpha arrestin, substrate of calcineurin; controls nutrient-mediated intracellular sorting of permease Gap1p; interacts with AP-1 subunit Apl4p; dephosphorylation of Aly1p required for the endocytosis of Dip5p; may regulate endocytosis of plasma membrane proteins by recruiting ubiquitin ligase Rsp5p to plasma membrane targets; ALY1 has a paralog, ALY2, that arose from the whole genome duplication
Top 10 interactors (score): RSP5 (0.972); LDB19 (0.933); ROD1 (0.926); BUL1 (0.892); BUL2 (0.891); ECM21 (0.891); ART5 (0.864); NPR1 (0.796); GAP1 (0.782); RIM8 (0.747); HER1 (0.745); ART10 (0.744); APL4 (0.702); DIP5 (0.695); SPO23 (0.671); LRG1 (0.638); CRM1 (0.63); APL2 (0.612); PEP8 (0.607); CHC1 (0.595)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:464906-467653:+ | gene-YKR021W_AKU4011 | rna-NM_001179811.4_AKU4011 | cds-NP_012946.3_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000113.1:175834-178581:- | gene-YKR021W_BG1 | rna-NM_001179811.4_BG1 | cds-NP_012946.3_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:486576-489323:+ | gene-YKR021W_Bruggeman | rna-NM_001179811.4_Bruggeman | cds-NP_012946.3_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:482317-485064:+ | gene-YKR021W_CAT1 | rna-NM_001179811.4_CAT1 | cds-NP_012946.3_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:477646-480393:+ | gene-YKR021W_CBS1585 | rna-NM_001179811.4_CBS1585 | cds-NP_012946.3_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:476474-479221:+ | gene-YKR021W_CBS436 | rna-NM_001179811.4_CBS436 | cds-NP_012946.3_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:461807-464554:+ | gene-YKR021W_CBS6412 | rna-NM_001179811.4_CBS6412 | cds-NP_012946.3_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:477474-480221:+ | gene-YKR021W_CBS6413 | rna-NM_001179811.4_CBS6413 | cds-NP_012946.3_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:478939-481723:+ | gene-YKR021W_CENPK1137D | rna-NM_001179811.4_CENPK1137D | cds-NP_012946.3_CENPK1137D | 97.7 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:475374-478121:+ | gene-YKR021W_EthanolRed | rna-NM_001179811.4_EthanolRed | cds-NP_012946.3_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:478304-481051:+ | gene-YKR021W_FaliES1 | rna-NM_001179811.4_FaliES1 | cds-NP_012946.3_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000077.1:72708-75455:- | gene-YKR021W_JAY291 | rna-NM_001179811.4_JAY291 | cds-NP_012946.3_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:485892-488639:+ | gene-YKR021W_MUCL30387 | rna-NM_001179811.4_MUCL30387 | cds-NP_012946.3_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:481583-484330:+ | gene-YKR021W_MUCL30388 | rna-NM_001179811.4_MUCL30388 | cds-NP_012946.3_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:476963-479710:+ | gene-YKR021W_MUCL39482 | rna-NM_001179811.4_MUCL39482 | cds-NP_012946.3_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:482735-485482:+ | gene-YKR021W_MUCL42920 | rna-NM_001179811.4_MUCL42920 | cds-NP_012946.3_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:479223-481970:+ | gene-YKR021W_NCIM3186 | rna-NM_001179811.4_NCIM3186 | cds-NP_012946.3_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:477170-479917:+ | gene-YKR021W_NCYC1407 | rna-NM_001179811.4_NCYC1407 | cds-NP_012946.3_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:502155-504902:+ | gene-YKR021W_PE2H3 | rna-NM_001179811.4_PE2H3 | cds-NP_012946.3_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:486878-489625:+ | gene-YKR021W_PE2H4 | rna-NM_001179811.4_PE2H4 | cds-NP_012946.3_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:479234-481981:+ | gene-YKR021W_S288C | rna-NM_001179811.4_S288C | cds-NP_012946.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000078.1:31767-34514:- | gene-YKR021W_SA1 | rna-NM_001179811.4_SA1 | cds-NP_012946.3_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:477559-480306:+ | gene-YKR021W_ThermosaccDry | rna-NM_001179811.4_ThermosaccDry | cds-NP_012946.3_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:477175-479922:+ | gene-YKR021W_VR1 | rna-NM_001179811.4_VR1 | cds-NP_012946.3_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:475606-478353:+ | gene-YKR021W_ZTW1 | rna-NM_001179811.4_ZTW1 | cds-NP_012946.3_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:501045-503789:+ | gene-YKR021W_Sparadoxus | rna-NM_001179811.4_Sparadoxus | cds-NP_012946.3_Sparadoxus | 90.3 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |