Gene name: ALT2
Reference locus (S288C): YDR111C
Gene biotype: protein_coding
Description: Probable alanine aminotransferase; Catalytically inactive alanine transaminase; expression is repressed in the presence of alanine and repression is mediated by Nrg1p; ALT2 has a paralog, ALT1, that arose from the whole genome duplication; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily
Top 10 interactors (score): FUM1 (0.98); AGX1 (0.967); ALT1 (0.954); AAT2 (0.94); AAT1 (0.939); GDH3 (0.934); GDH1 (0.933); GDH2 (0.928); ARG7 (0.927); TPI1 (0.921); ARG2 (0.909); YFR006W (0.885); UGA1 (0.881); SER3 (0.869); ACO1 (0.867); IDH2 (0.856); SER33 (0.856); ECM38 (0.847); IDH1 (0.845); IDP3 (0.834)
Homologues (species, bitscore): GPT2 (Homo sapiens, 433.0); Gpt2 (Mus musculus, 430.6); gpt2l (Danio rerio, 424.9); gpt (Xenopus tropicalis, 424.1); CG1640 (Drosophila melanogaster, 366.7); C32F10.8 (Caenorhabditis elegans, 395.6); AlaAT1 (Arabidopsis thaliana, 438.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:649165-650688:- | gene-YDR111C_AKU4011 | rna-NM_001180419.1_AKU4011 | cds-NP_010396.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:474190-475713:+ | gene-YDR111C_BG1 | rna-NM_001180419.1_BG1 | cds-NP_010396.1_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:681235-682758:- | gene-YDR111C_Bruggeman | rna-NM_001180419.1_Bruggeman | cds-NP_010396.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:667975-669498:- | gene-YDR111C_CAT1 | rna-NM_001180419.1_CAT1 | cds-NP_010396.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:640203-641726:- | gene-YDR111C_CBS1585 | rna-NM_001180419.1_CBS1585 | cds-NP_010396.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:666098-667621:- | gene-YDR111C_CBS436 | rna-NM_001180419.1_CBS436 | cds-NP_010396.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:636555-638078:- | gene-YDR111C_CBS6412 | rna-NM_001180419.1_CBS6412 | cds-NP_010396.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:665532-667055:- | gene-YDR111C_CBS6413 | rna-NM_001180419.1_CBS6413 | cds-NP_010396.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:670682-672205:- | gene-YDR111C_CENPK1137D | rna-NM_001180419.1_CENPK1137D | cds-NP_010396.1_CENPK1137D | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:650943-652466:- | gene-YDR111C_EthanolRed | rna-NM_001180419.1_EthanolRed | cds-NP_010396.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:657737-659260:- | gene-YDR111C_FaliES1 | rna-NM_001180419.1_FaliES1 | cds-NP_010396.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000002.1:9841-11364:- | gene-YDR111C_JAY291 | rna-NM_001180419.1_JAY291 | cds-NP_010396.1_JAY291 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:667159-668682:- | gene-YDR111C_MUCL30387 | rna-NM_001180419.1_MUCL30387 | cds-NP_010396.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:656177-657701:- | gene-YDR111C_MUCL30388 | rna-NM_001180419.1_MUCL30388 | cds-NP_010396.1_MUCL30388 | 99.4 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:641546-643069:- | gene-YDR111C_MUCL39482 | rna-NM_001180419.1_MUCL39482 | cds-NP_010396.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:579506-581029:- | gene-YDR111C_MUCL42920 | rna-NM_001180419.1_MUCL42920 | cds-NP_010396.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:678164-679687:- | gene-YDR111C_NCIM3186 | rna-NM_001180419.1_NCIM3186 | cds-NP_010396.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:640950-642473:- | gene-YDR111C_NCYC1407 | rna-NM_001180419.1_NCYC1407 | cds-NP_010396.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:660274-661797:- | gene-YDR111C_PE2H3 | rna-NM_001180419.1_PE2H3 | cds-NP_010396.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:659579-661102:- | gene-YDR111C_PE2H4 | rna-NM_001180419.1_PE2H4 | cds-NP_010396.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:678241-679764:- | gene-YDR111C_S288C | rna-NM_001180419.1_S288C | cds-NP_010396.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000009.1:26890-28413:- | gene-YDR111C_SA1 | rna-NM_001180419.1_SA1 | cds-NP_010396.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:657259-658782:- | gene-YDR111C_ThermosaccDry | rna-NM_001180419.1_ThermosaccDry | cds-NP_010396.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:670596-672119:- | gene-YDR111C_VR1 | rna-NM_001180419.1_VR1 | cds-NP_010396.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:654845-656368:- | gene-YDR111C_ZTW1 | rna-NM_001180419.1_ZTW1 | cds-NP_010396.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:659278-660801:- | gene-YDR111C_Sparadoxus | rna-NM_001180419.1_Sparadoxus | cds-NP_010396.1_Sparadoxus | 89.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |