Gene name: ALG8
Reference locus (S288C): YOR067C
Gene biotype: protein_coding
Description: Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase; Glucosyl transferase; involved in N-linked glycosylation; adds glucose to the dolichol-linked oligosaccharide precursor prior to transfer to protein during lipid-linked oligosaccharide biosynthesis; similar to Alg6p; human homolog ALG8 can complement yeast null mutant; Belongs to the ALG6/ALG8 glucosyltransferase family
Top 10 interactors (score): DIE2 (0.999); ALG12 (0.996); ALG5 (0.995); ALG9 (0.994); ALG3 (0.992); ALG6 (0.982); ALG11 (0.968); CNE1 (0.96); ROT2 (0.948); ALG1 (0.946); STT3 (0.94); CWH41 (0.938); OST5 (0.936); OST6 (0.93); ALG13 (0.907); ALG7 (0.902); WBP1 (0.884); SWP1 (0.86); YLR446W (0.859); DPM1 (0.808)
Homologues (species, bitscore): ALG8 (Homo sapiens, 324.3); Alg8 (Mus musculus, 317.0); alg8 (Danio rerio, 316.2); alg8 (Xenopus tropicalis, 291.2); xit (Drosophila melanogaster, 306.6); C08H9.3 (Caenorhabditis elegans, 225.7); AT2G44660 (Arabidopsis thaliana, 300.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:436063-437796:- | gene-YOR067C_AKU4011 | rna-NM_001183486.1_AKU4011 | cds-NP_014710.1_AKU4011 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000171.1:141905-143638:+ | gene-YOR067C_BG1 | rna-NM_001183486.1_BG1 | cds-NP_014710.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:438777-440510:- | gene-YOR067C_Bruggeman | rna-NM_001183486.1_Bruggeman | cds-NP_014710.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:437533-439266:- | gene-YOR067C_CAT1 | rna-NM_001183486.1_CAT1 | cds-NP_014710.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:430783-432516:- | gene-YOR067C_CBS1585 | rna-NM_001183486.1_CBS1585 | cds-NP_014710.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:435061-436794:- | gene-YOR067C_CBS436 | rna-NM_001183486.1_CBS436 | cds-NP_014710.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:430073-431806:- | gene-YOR067C_CBS6412 | rna-NM_001183486.1_CBS6412 | cds-NP_014710.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:437390-439123:- | gene-YOR067C_CBS6413 | rna-NM_001183486.1_CBS6413 | cds-NP_014710.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:451711-453444:- | gene-YOR067C_CENPK1137D | rna-NM_001183486.1_CENPK1137D | cds-NP_014710.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:432775-434508:- | gene-YOR067C_EthanolRed | rna-NM_001183486.1_EthanolRed | cds-NP_014710.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:436104-437837:- | gene-YOR067C_FaliES1 | rna-NM_001183486.1_FaliES1 | cds-NP_014710.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000407.1:6520-8253:+ | gene-YOR067C_JAY291 | rna-NM_001183486.1_JAY291 | cds-NP_014710.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:443559-445292:- | gene-YOR067C_MUCL30387 | rna-NM_001183486.1_MUCL30387 | cds-NP_014710.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:447969-449702:- | gene-YOR067C_MUCL30388 | rna-NM_001183486.1_MUCL30388 | cds-NP_014710.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:438251-439984:- | gene-YOR067C_MUCL39482 | rna-NM_001183486.1_MUCL39482 | cds-NP_014710.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:453382-455115:- | gene-YOR067C_MUCL42920 | rna-NM_001183486.1_MUCL42920 | cds-NP_014710.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:451618-453351:- | gene-YOR067C_NCIM3186 | rna-NM_001183486.1_NCIM3186 | cds-NP_014710.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:445169-446902:- | gene-YOR067C_NCYC1407 | rna-NM_001183486.1_NCYC1407 | cds-NP_014710.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:443762-445495:- | gene-YOR067C_PE2H3 | rna-NM_001183486.1_PE2H3 | cds-NP_014710.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:454143-455876:- | gene-YOR067C_PE2H4 | rna-NM_001183486.1_PE2H4 | cds-NP_014710.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:451729-453462:- | gene-YOR067C_S288C | rna-NM_001183486.1_S288C | cds-NP_014710.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000091.1:34184-35917:+ | gene-YOR067C_SA1 | rna-NM_001183486.1_SA1 | cds-NP_014710.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:435260-436993:- | gene-YOR067C_ThermosaccDry | rna-NM_001183486.1_ThermosaccDry | cds-NP_014710.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:436499-438232:- | gene-YOR067C_VR1 | rna-NM_001183486.1_VR1 | cds-NP_014710.1_VR1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:169260-170993:- | gene-YOR067C_ZTW1 | rna-NM_001183486.1_ZTW1 | cds-NP_014710.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:440822-442555:- | gene-YOR067C_Sparadoxus | rna-NM_001183486.1_Sparadoxus | cds-NP_014710.1_Sparadoxus | 91.2 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |