Gene name: ALG6
Reference locus (S288C): YOR002W
Gene biotype: protein_coding
Description: Dolichyl-P-Glc:Man(9)GlcNAc(2)-PP-dolichol alpha-1,3-glucosyltransferase; Alpha 1,3 glucosyltransferase; involved in transfer of oligosaccharides from dolichyl pyrophosphate to asparagine residues of proteins during N-linked protein glycosylation; C998T transition in human ortholog ALG6 causes carbohydrate-deficient glycoprotein syndrome type-Ic; wild-type human ortholog ALG6 can partially complement yeast alg6 mutant; Belongs to the ALG6/ALG8 glucosyltransferase family
Top 10 interactors (score): ALG9 (0.999); ALG5 (0.999); ALG3 (0.999); ALG12 (0.996); DIE2 (0.995); ALG8 (0.982); ALG11 (0.974); ALG1 (0.96); STT3 (0.958); DPM1 (0.937); ALG13 (0.935); OST5 (0.922); CWH41 (0.922); ALG7 (0.918); DFG10 (0.915); ROT2 (0.914); OST6 (0.901); PMT2 (0.881); OST3 (0.865); KRE5 (0.863)
Homologues (species, bitscore): ALG6 (Homo sapiens, 297.4); Alg6 (Mus musculus, 291.2); alg6 (Danio rerio, 278.1); alg6 (Xenopus tropicalis, 290.0); gny (Drosophila melanogaster, 290.0); C08B11.8 (Caenorhabditis elegans, 272.3); AT5G38460 (Arabidopsis thaliana, 304.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:313775-315409:+ | gene-YOR002W_AKU4011 | rna-NM_001183421.1_AKU4011 | cds-NP_014644.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000152.1:129398-131032:+ | gene-YOR002W_BG1 | rna-NM_001183421.1_BG1 | cds-NP_014644.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:316550-318184:+ | gene-YOR002W_Bruggeman | rna-NM_001183421.1_Bruggeman | cds-NP_014644.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:314704-316338:+ | gene-YOR002W_CAT1 | rna-NM_001183421.1_CAT1 | cds-NP_014644.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:308451-310085:+ | gene-YOR002W_CBS1585 | rna-NM_001183421.1_CBS1585 | cds-NP_014644.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:312730-314364:+ | gene-YOR002W_CBS436 | rna-NM_001183421.1_CBS436 | cds-NP_014644.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:307755-309389:+ | gene-YOR002W_CBS6412 | rna-NM_001183421.1_CBS6412 | cds-NP_014644.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:315288-316922:+ | gene-YOR002W_CBS6413 | rna-NM_001183421.1_CBS6413 | cds-NP_014644.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:329098-330732:+ | gene-YOR002W_CENPK1137D | rna-NM_001183421.1_CENPK1137D | cds-NP_014644.1_CENPK1137D | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:310538-312172:+ | gene-YOR002W_EthanolRed | rna-NM_001183421.1_EthanolRed | cds-NP_014644.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:313865-315499:+ | gene-YOR002W_FaliES1 | rna-NM_001183421.1_FaliES1 | cds-NP_014644.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000015.1:13730-15364:- | gene-YOR002W_JAY291 | rna-NM_001183421.1_JAY291 | cds-NP_014644.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:320765-322399:+ | gene-YOR002W_MUCL30387 | rna-NM_001183421.1_MUCL30387 | cds-NP_014644.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:324201-325835:+ | gene-YOR002W_MUCL30388 | rna-NM_001183421.1_MUCL30388 | cds-NP_014644.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:315934-317568:+ | gene-YOR002W_MUCL39482 | rna-NM_001183421.1_MUCL39482 | cds-NP_014644.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:330788-332422:+ | gene-YOR002W_MUCL42920 | rna-NM_001183421.1_MUCL42920 | cds-NP_014644.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:329306-330940:+ | gene-YOR002W_NCIM3186 | rna-NM_001183421.1_NCIM3186 | cds-NP_014644.1_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:322619-324253:+ | gene-YOR002W_NCYC1407 | rna-NM_001183421.1_NCYC1407 | cds-NP_014644.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:317322-318956:+ | gene-YOR002W_PE2H3 | rna-NM_001183421.1_PE2H3 | cds-NP_014644.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:327701-329335:+ | gene-YOR002W_PE2H4 | rna-NM_001183421.1_PE2H4 | cds-NP_014644.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:329417-331051:+ | gene-YOR002W_S288C | rna-NM_001183421.1_S288C | cds-NP_014644.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000001.1:297389-299023:+ | gene-YOR002W_SA1 | rna-NM_001183421.1_SA1 | cds-NP_014644.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:312436-314070:+ | gene-YOR002W_ThermosaccDry | rna-NM_001183421.1_ThermosaccDry | cds-NP_014644.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:313273-314907:+ | gene-YOR002W_VR1 | rna-NM_001183421.1_VR1 | cds-NP_014644.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:47101-48735:+ | gene-YOR002W_ZTW1 | rna-NM_001183421.1_ZTW1 | cds-NP_014644.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:320907-322541:+ | gene-YOR002W_Sparadoxus | rna-NM_001183421.1_Sparadoxus | cds-NP_014644.1_Sparadoxus | 91.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |