Gene name: ALG3
Reference locus (S288C): YBL082C
Gene biotype: protein_coding
Description: Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase; Dolichol-P-Man dependent alpha(1-3) mannosyltransferase; involved in synthesis of dolichol-linked oligosaccharide donor for N-linked glycosylation of proteins; G353A missense mutation in human ortholog ALG3 implicated in carbohydrate deficient glycoprotein syndrome type IV, which is characterized by microcephaly, severe epilepsy, minimal psychomotor development, partial deficiency of sialic acids in serum glycoproteins; wild-type human ALG3 can complement yeast alg3 mutant; Belongs to the glycosyltransferase 58 family
Top 10 interactors (score): ALG6 (0.999); ALG9 (0.999); ALG5 (0.999); ALG12 (0.999); ALG11 (0.997); ALG8 (0.992); DIE2 (0.989); STT3 (0.973); DPM1 (0.968); ALG1 (0.966); OST3 (0.945); GPI17 (0.922); OST1 (0.919); GPI10 (0.919); GPI14 (0.904); ERV1 (0.896); GPI18 (0.892); OST5 (0.865); OST6 (0.856); SWP1 (0.846)
Homologues (species, bitscore): ALG3 (Homo sapiens, 213.4); Alg3 (Mus musculus, 214.5); alg3 (Danio rerio, 235.0); alg3 (Xenopus tropicalis, 228.8); l(2)not (Drosophila melanogaster, 189.9); K09E4.2 (Caenorhabditis elegans, 214.5); ALG3 (Arabidopsis thaliana, 219.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:63303-64679:- | gene-YBL082C_AKU4011 | rna-NM_001178322.1_AKU4011 | cds-NP_009471.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000179.1:53987-55363:- | gene-YBL082C_BG1 | rna-NM_001178322.1_BG1 | cds-NP_009471.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:63913-65289:- | gene-YBL082C_Bruggeman | rna-NM_001178322.1_Bruggeman | cds-NP_009471.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:65872-67248:- | gene-YBL082C_CAT1 | rna-NM_001178322.1_CAT1 | cds-NP_009471.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:55402-56778:- | gene-YBL082C_CBS1585 | rna-NM_001178322.1_CBS1585 | cds-NP_009471.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:64168-65544:- | gene-YBL082C_CBS436 | rna-NM_001178322.1_CBS436 | cds-NP_009471.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:54795-56171:- | gene-YBL082C_CBS6412 | rna-NM_001178322.1_CBS6412 | cds-NP_009471.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:61447-62823:- | gene-YBL082C_CBS6413 | rna-NM_001178322.1_CBS6413 | cds-NP_009471.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:63406-64782:- | gene-YBL082C_CENPK1137D | rna-NM_001178322.1_CENPK1137D | cds-NP_009471.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:77527-78903:- | gene-YBL082C_EthanolRed | rna-NM_001178322.1_EthanolRed | cds-NP_009471.1_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:77656-79032:- | gene-YBL082C_FaliES1 | rna-NM_001178322.1_FaliES1 | cds-NP_009471.1_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000019.1:9576-10952:- | gene-YBL082C_JAY291 | rna-NM_001178322.1_JAY291 | cds-NP_009471.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:63030-64406:- | gene-YBL082C_MUCL30387 | rna-NM_001178322.1_MUCL30387 | cds-NP_009471.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:64568-65944:- | gene-YBL082C_MUCL30388 | rna-NM_001178322.1_MUCL30388 | cds-NP_009471.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:55583-56959:- | gene-YBL082C_MUCL39482 | rna-NM_001178322.1_MUCL39482 | cds-NP_009471.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:62371-63747:- | gene-YBL082C_MUCL42920 | rna-NM_001178322.1_MUCL42920 | cds-NP_009471.1_MUCL42920 | 99.1 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:69548-70924:- | gene-YBL082C_NCIM3186 | rna-NM_001178322.1_NCIM3186 | cds-NP_009471.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:57194-58570:- | gene-YBL082C_NCYC1407 | rna-NM_001178322.1_NCYC1407 | cds-NP_009471.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:63490-64866:- | gene-YBL082C_PE2H3 | rna-NM_001178322.1_PE2H3 | cds-NP_009471.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:61134-62510:- | gene-YBL082C_PE2H4 | rna-NM_001178322.1_PE2H4 | cds-NP_009471.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:69751-71127:- | gene-YBL082C_S288C | rna-NM_001178322.1_S288C | cds-NP_009471.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000004.1:53850-55226:- | gene-YBL082C_SA1 | rna-NM_001178322.1_SA1 | cds-NP_009471.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:77617-78993:- | gene-YBL082C_ThermosaccDry | rna-NM_001178322.1_ThermosaccDry | cds-NP_009471.1_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:59822-61198:- | gene-YBL082C_VR1 | rna-NM_001178322.1_VR1 | cds-NP_009471.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:54837-56213:- | gene-YBL082C_ZTW1 | rna-NM_001178322.1_ZTW1 | cds-NP_009471.1_ZTW1 | 99.2 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:89577-90953:- | gene-YBL082C_Sparadoxus | rna-NM_001178322.1_Sparadoxus | cds-NP_009471.1_Sparadoxus | 88.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |