ALG13 (YGL047W)


Gene profile

Gene name: ALG13
Reference locus (S288C): YGL047W
Gene biotype: protein_coding

Description: UDP-N-acetylglucosamine transferase subunit ALG13; Catalytic component of UDP-GlcNAc transferase; required for the second step of dolichyl-linked oligosaccharide synthesis; anchored to the ER membrane via interaction with Alg14p; similar to bacterial and human glycosyltransferases; protein abundance increases in response to DNA replication stress; both human homologs ALG13 and ALG14 are required to complement yeast alg13 mutant

Top 10 interactors (score): ALG7 (0.999); ALG14 (0.999); ALG1 (0.998); ALG11 (0.981); DIE2 (0.96); ALG6 (0.935); ALG12 (0.915); ALG8 (0.907); ALG9 (0.907); ALG5 (0.892); RFT1 (0.862); ALG3 (0.838); DPM1 (0.779); STT3 (0.77); OST2 (0.747); GNT1 (0.709); MIP1 (0.696); GPI12 (0.671); ADO1 (0.667); AMS1 (0.647)

Homologues (species, bitscore): ALG13 (Homo sapiens, 70.5); Alg13 (Mus musculus, 67.8); zgc:92907 (Danio rerio, 83.6); alg13 (Xenopus tropicalis, 72.0); CG14512 (Drosophila melanogaster, 66.2); hpo-17 (Caenorhabditis elegans, 60.5); AT4G16710 (Arabidopsis thaliana, 83.6)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005301.1:413627-414235:+ gene-YGL047W_AKU4011 rna-NM_001180912.1_AKU4011 cds-NP_011468.1_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000060.1:161894-162502:- gene-YGL047W_BG1 rna-NM_001180912.1_BG1 cds-NP_011468.1_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005509.1:414196-414804:+ gene-YGL047W_Bruggeman rna-NM_001180912.1_Bruggeman cds-NP_011468.1_Bruggeman 99.0 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005525.1:412609-413217:+ gene-YGL047W_CAT1 rna-NM_001180912.1_CAT1 cds-NP_011468.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005365.1:415090-415698:+ gene-YGL047W_CBS1585 rna-NM_001180912.1_CBS1585 cds-NP_011468.1_CBS1585 99.6 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005349.1:409216-409824:+ gene-YGL047W_CBS436 rna-NM_001180912.1_CBS436 cds-NP_011468.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005333.1:407270-407878:+ gene-YGL047W_CBS6412 rna-NM_001180912.1_CBS6412 cds-NP_011468.1_CBS6412 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005317.1:411307-411915:+ gene-YGL047W_CBS6413 rna-NM_001180912.1_CBS6413 cds-NP_011468.1_CBS6413 99.6 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001528.1:411394-412002:+ gene-YGL047W_CENPK1137D rna-NM_001180912.1_CENPK1137D cds-NP_011468.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005477.1:402003-402611:+ gene-YGL047W_EthanolRed rna-NM_001180912.1_EthanolRed cds-NP_011468.1_EthanolRed 99.8 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005541.1:405266-405874:+ gene-YGL047W_FaliES1 rna-NM_001180912.1_FaliES1 cds-NP_011468.1_FaliES1 99.8 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000165.1:10957-11565:- gene-YGL047W_JAY291 rna-NM_001180912.1_JAY291 cds-NP_011468.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005413.1:411400-412008:+ gene-YGL047W_MUCL30387 rna-NM_001180912.1_MUCL30387 cds-NP_011468.1_MUCL30387 99.3 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005445.1:414442-415050:+ gene-YGL047W_MUCL30388 rna-NM_001180912.1_MUCL30388 cds-NP_011468.1_MUCL30388 98.6 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005285.1:410883-411491:+ gene-YGL047W_MUCL39482 rna-NM_001180912.1_MUCL39482 cds-NP_011468.1_MUCL39482 99.8 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005429.1:419301-419909:+ gene-YGL047W_MUCL42920 rna-NM_001180912.1_MUCL42920 cds-NP_011468.1_MUCL42920 99.6 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011816.1:411552-412160:+ gene-YGL047W_NCIM3186 rna-NM_001180912.1_NCIM3186 cds-NP_011468.1_NCIM3186 98.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005269.1:405008-405616:+ gene-YGL047W_NCYC1407 rna-NM_001180912.1_NCYC1407 cds-NP_011468.1_NCYC1407 99.8 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994146.1:407581-408189:+ gene-YGL047W_PE2H3 rna-NM_001180912.1_PE2H3 cds-NP_011468.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999878.1:412631-413239:+ gene-YGL047W_PE2H4 rna-NM_001180912.1_PE2H4 cds-NP_011468.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001139.9:411552-412160:+ gene-YGL047W_S288C rna-NM_001180912.1_S288C cds-NP_011468.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000021.1:143468-144076:- gene-YGL047W_SA1 rna-NM_001180912.1_SA1 cds-NP_011468.1_SA1 99.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005493.1:424630-425238:+ gene-YGL047W_ThermosaccDry rna-NM_001180912.1_ThermosaccDry cds-NP_011468.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005461.1:514576-515184:+ gene-YGL047W_VR1 rna-NM_001180912.1_VR1 cds-NP_011468.1_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000014.1:402870-403478:+ gene-YGL047W_ZTW1 rna-NM_001180912.1_ZTW1 cds-NP_011468.1_ZTW1 99.8 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047493.1:412289-412897:+ gene-YGL047W_Sparadoxus rna-NM_001180912.1_Sparadoxus cds-NP_011468.1_Sparadoxus 88.0 100.0 Verified 1 1 1 False True False False False

Additional files