ALG12 (YNR030W)


Gene profile

Gene name: ALG12
Reference locus (S288C): YNR030W
Gene biotype: protein_coding

Description: Alpha-1,6-mannosyltransferase localized to the ER; responsible for addition of alpha-1,6 mannose to dolichol-linked Man7GlcNAc2; acts in the dolichol pathway for N-glycosylation; human homolog ALG12 complements yeast null mutant

Top 10 interactors (score): ALG9 (0.999); ALG3 (0.999); ALG5 (0.997); ALG6 (0.996); ALG8 (0.996); DIE2 (0.994); STT3 (0.982); ALG11 (0.981); OST5 (0.973); OST3 (0.945); ALG1 (0.944); WBP1 (0.938); OST6 (0.92); ALG13 (0.915); ALG14 (0.906); ALG7 (0.899); GPI10 (0.886); DPM1 (0.877); YOS9 (0.876); GAA1 (0.861)

Homologues (species, bitscore): ALG12 (Homo sapiens, 221.9); Alg12 (Mus musculus, 206.8); alg12 (Danio rerio, 222.2); alg12 (Xenopus tropicalis, 209.9); CG8412 (Drosophila melanogaster, 199.1); ZC513.5 (Caenorhabditis elegans, 190.7); ALG12 (Arabidopsis thaliana, 192.6)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005308.1:662444-664099:+ gene-YNR030W_AKU4011 rna-NM_001183207.1_AKU4011 cds-NP_014427.1_AKU4011 98.7 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000155.1:570309-571964:+ gene-YNR030W_BG1 rna-NM_001183207.1_BG1 cds-NP_014427.1_BG1 99.7 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005516.1:679897-681552:+ gene-YNR030W_Bruggeman rna-NM_001183207.1_Bruggeman cds-NP_014427.1_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005532.1:714154-715809:+ gene-YNR030W_CAT1 rna-NM_001183207.1_CAT1 cds-NP_014427.1_CAT1 99.6 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005372.1:668199-669854:+ gene-YNR030W_CBS1585 rna-NM_001183207.1_CBS1585 cds-NP_014427.1_CBS1585 98.7 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005356.1:729868-731523:+ gene-YNR030W_CBS436 rna-NM_001183207.1_CBS436 cds-NP_014427.1_CBS436 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005340.1:657387-659042:+ gene-YNR030W_CBS6412 rna-NM_001183207.1_CBS6412 cds-NP_014427.1_CBS6412 98.7 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005324.1:659092-660747:+ gene-YNR030W_CBS6413 rna-NM_001183207.1_CBS6413 cds-NP_014427.1_CBS6413 98.7 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001535.1:672546-674201:+ gene-YNR030W_CENPK1137D rna-NM_001183207.1_CENPK1137D cds-NP_014427.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005484.1:664136-665791:+ gene-YNR030W_EthanolRed rna-NM_001183207.1_EthanolRed cds-NP_014427.1_EthanolRed 98.7 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005548.1:655339-656994:+ gene-YNR030W_FaliES1 rna-NM_001183207.1_FaliES1 cds-NP_014427.1_FaliES1 98.7 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000037.1:45786-47441:- gene-YNR030W_JAY291 rna-NM_001183207.1_JAY291 cds-NP_014427.1_JAY291 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005420.1:677654-679309:+ gene-YNR030W_MUCL30387 rna-NM_001183207.1_MUCL30387 cds-NP_014427.1_MUCL30387 99.3 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005452.1:718477-720132:+ gene-YNR030W_MUCL30388 rna-NM_001183207.1_MUCL30388 cds-NP_014427.1_MUCL30388 99.6 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005292.1:659699-661354:+ gene-YNR030W_MUCL39482 rna-NM_001183207.1_MUCL39482 cds-NP_014427.1_MUCL39482 98.7 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005436.1:663872-665527:+ gene-YNR030W_MUCL42920 rna-NM_001183207.1_MUCL42920 cds-NP_014427.1_MUCL42920 99.3 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011823.1:678768-680423:+ gene-YNR030W_NCIM3186 rna-NM_001183207.1_NCIM3186 cds-NP_014427.1_NCIM3186 98.9 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005276.1:662207-663862:+ gene-YNR030W_NCYC1407 rna-NM_001183207.1_NCYC1407 cds-NP_014427.1_NCYC1407 98.6 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994153.1:663299-664954:+ gene-YNR030W_PE2H3 rna-NM_001183207.1_PE2H3 cds-NP_014427.1_PE2H3 99.7 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999885.1:664617-666272:+ gene-YNR030W_PE2H4 rna-NM_001183207.1_PE2H4 cds-NP_014427.1_PE2H4 99.7 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001146.8:678799-680454:+ gene-YNR030W_S288C rna-NM_001183207.1_S288C cds-NP_014427.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000074.1:45936-47591:- gene-YNR030W_SA1 rna-NM_001183207.1_SA1 cds-NP_014427.1_SA1 99.6 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005500.1:655676-657331:+ gene-YNR030W_ThermosaccDry rna-NM_001183207.1_ThermosaccDry cds-NP_014427.1_ThermosaccDry 98.7 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005468.1:697674-699329:+ gene-YNR030W_VR1 rna-NM_001183207.1_VR1 cds-NP_014427.1_VR1 99.8 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000030.1:565085-566740:+ gene-YNR030W_ZTW1 rna-NM_001183207.1_ZTW1 cds-NP_014427.1_ZTW1 98.9 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047500.1:669767-671422:+ gene-YNR030W_Sparadoxus rna-NM_001183207.1_Sparadoxus cds-NP_014427.1_Sparadoxus 88.5 100.0 Verified 1 1 1 False True False False False

Additional files