Gene name: ALF1
Reference locus (S288C): YNL148C
Gene biotype: protein_coding
Description: Tubulin-specific chaperone B; Alpha-tubulin folding protein; similar to mammalian cofactor B; Alf1p-GFP localizes to cytoplasmic microtubules; required for the folding of alpha-tubulin and may play an additional role in microtubule maintenance; Belongs to the TBCB family
Top 10 interactors (score): PAC2 (0.999); CIN1 (0.991); RBL2 (0.99); TUB3 (0.986); TUB1 (0.986); CIN4 (0.971); TUB2 (0.927); CCT5 (0.813); URM1 (0.753); PNS1 (0.747); SBA1 (0.732); TRE1 (0.691); YPT7 (0.688); ARP5 (0.652); NPL4 (0.652); CDC16 (0.649); AOS1 (0.635); AST1 (0.617); PMP1 (0.617); UBA1 (0.602)
Homologues (species, bitscore): TBCB (Homo sapiens, 73.9); Tbcb (Mus musculus, 66.2); tbcb (Danio rerio, 73.6); tbcb (Xenopus tropicalis, 68.6); TBCB (Drosophila melanogaster, 68.9); tbcb-1 (Caenorhabditis elegans, 64.3); EMB2804 (Arabidopsis thaliana, 52.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:343627-344391:- | gene-YNL148C_AKU4011 | rna-NM_001182986.1_AKU4011 | cds-NP_014251.1_AKU4011 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:247648-248412:- | gene-YNL148C_BG1 | rna-NM_001182986.1_BG1 | cds-NP_014251.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:353695-354459:- | gene-YNL148C_Bruggeman | rna-NM_001182986.1_Bruggeman | cds-NP_014251.1_Bruggeman | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:396613-397377:- | gene-YNL148C_CAT1 | rna-NM_001182986.1_CAT1 | cds-NP_014251.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:344277-345041:- | gene-YNL148C_CBS1585 | rna-NM_001182986.1_CBS1585 | cds-NP_014251.1_CBS1585 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:412628-413392:- | gene-YNL148C_CBS436 | rna-NM_001182986.1_CBS436 | cds-NP_014251.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:339683-340447:- | gene-YNL148C_CBS6412 | rna-NM_001182986.1_CBS6412 | cds-NP_014251.1_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:340711-341475:- | gene-YNL148C_CBS6413 | rna-NM_001182986.1_CBS6413 | cds-NP_014251.1_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:343753-344517:- | gene-YNL148C_CENPK1137D | rna-NM_001182986.1_CENPK1137D | cds-NP_014251.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:340612-341376:- | gene-YNL148C_EthanolRed | rna-NM_001182986.1_EthanolRed | cds-NP_014251.1_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:336525-337289:- | gene-YNL148C_FaliES1 | rna-NM_001182986.1_FaliES1 | cds-NP_014251.1_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000439.1:6369-7133:+ | gene-YNL148C_JAY291 | rna-NM_001182986.1_JAY291 | cds-NP_014251.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:349763-350527:- | gene-YNL148C_MUCL30387 | rna-NM_001182986.1_MUCL30387 | cds-NP_014251.1_MUCL30387 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:384315-385079:- | gene-YNL148C_MUCL30388 | rna-NM_001182986.1_MUCL30388 | cds-NP_014251.1_MUCL30388 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:341517-342281:- | gene-YNL148C_MUCL39482 | rna-NM_001182986.1_MUCL39482 | cds-NP_014251.1_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:343916-344680:- | gene-YNL148C_MUCL42920 | rna-NM_001182986.1_MUCL42920 | cds-NP_014251.1_MUCL42920 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:349876-350640:- | gene-YNL148C_NCIM3186 | rna-NM_001182986.1_NCIM3186 | cds-NP_014251.1_NCIM3186 | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:343611-344375:- | gene-YNL148C_NCYC1407 | rna-NM_001182986.1_NCYC1407 | cds-NP_014251.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:340607-341371:- | gene-YNL148C_PE2H3 | rna-NM_001182986.1_PE2H3 | cds-NP_014251.1_PE2H3 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:339995-340759:- | gene-YNL148C_PE2H4 | rna-NM_001182986.1_PE2H4 | cds-NP_014251.1_PE2H4 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:349907-350671:- | gene-YNL148C_S288C | rna-NM_001182986.1_S288C | cds-NP_014251.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000018.1:62873-63637:+ | gene-YNL148C_SA1 | rna-NM_001182986.1_SA1 | cds-NP_014251.1_SA1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:337382-338146:- | gene-YNL148C_ThermosaccDry | rna-NM_001182986.1_ThermosaccDry | cds-NP_014251.1_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:355928-356692:- | gene-YNL148C_VR1 | rna-NM_001182986.1_VR1 | cds-NP_014251.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:247202-247966:- | gene-YNL148C_ZTW1 | rna-NM_001182986.1_ZTW1 | cds-NP_014251.1_ZTW1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:348158-348922:- | gene-YNL148C_Sparadoxus | rna-NM_001182986.1_Sparadoxus | cds-NP_014251.1_Sparadoxus | 86.1 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |