ALE1 (YOR175C)


Gene profile

Gene name: ALE1
Reference locus (S288C): YOR175C
Gene biotype: protein_coding

Description: Broad-specificity lysophospholipid acyltransferase; part of MBOAT family of membrane-bound O-acyltransferases; key component of Lands cycle; may have role in fatty acid exchange at sn-2 position of mature glycerophospholipids; Belongs to the membrane-bound acyltransferase family

Top 10 interactors (score): SLC1 (0.996); LRO1 (0.993); PSD1 (0.992); SCT1 (0.991); GPT2 (0.991); PSD2 (0.985); CHO2 (0.984); OPI3 (0.984); TAZ1 (0.983); EPT1 (0.98); TGL5 (0.979); TGL4 (0.976); SPO14 (0.974); TGL3 (0.973); AYR1 (0.973); CDS1 (0.97); GEP4 (0.97); CRD1 (0.969); NTE1 (0.969); CPT1 (0.963)

Homologues (species, bitscore): MBOAT2 (Homo sapiens, 187.2); Mboat1 (Mus musculus, 184.1); mboat1 (Danio rerio, 186.8); mboat1 (Xenopus tropicalis, 185.7); oys (Drosophila melanogaster, 190.7); mboa-3 (Caenorhabditis elegans, 156.0); LPLAT1 (Arabidopsis thaliana, 159.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005309.1:657454-659313:- gene-YOR175C_AKU4011 rna-NM_001183594.1_AKU4011 cds-NP_014818.1_AKU4011 99.6 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000123.1:59208-61067:- gene-YOR175C_BG1 rna-NM_001183594.1_BG1 cds-NP_014818.1_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005517.1:641527-643386:- gene-YOR175C_Bruggeman rna-NM_001183594.1_Bruggeman cds-NP_014818.1_Bruggeman 99.8 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005533.1:641546-643405:- gene-YOR175C_CAT1 rna-NM_001183594.1_CAT1 cds-NP_014818.1_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005373.1:639949-641808:- gene-YOR175C_CBS1585 rna-NM_001183594.1_CBS1585 cds-NP_014818.1_CBS1585 99.6 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005357.1:638243-640102:- gene-YOR175C_CBS436 rna-NM_001183594.1_CBS436 cds-NP_014818.1_CBS436 99.9 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005341.1:637561-639420:- gene-YOR175C_CBS6412 rna-NM_001183594.1_CBS6412 cds-NP_014818.1_CBS6412 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005325.1:646242-648101:- gene-YOR175C_CBS6413 rna-NM_001183594.1_CBS6413 cds-NP_014818.1_CBS6413 99.6 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001536.1:659571-661430:- gene-YOR175C_CENPK1137D rna-NM_001183594.1_CENPK1137D cds-NP_014818.1_CENPK1137D 99.9 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005485.1:633657-635516:- gene-YOR175C_EthanolRed rna-NM_001183594.1_EthanolRed cds-NP_014818.1_EthanolRed 99.7 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005549.1:638510-640369:- gene-YOR175C_FaliES1 rna-NM_001183594.1_FaliES1 cds-NP_014818.1_FaliES1 99.7 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000070.1:3173-5032:+ gene-YOR175C_JAY291 rna-NM_001183594.1_JAY291 cds-NP_014818.1_JAY291 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005421.1:646334-648193:- gene-YOR175C_MUCL30387 rna-NM_001183594.1_MUCL30387 cds-NP_014818.1_MUCL30387 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005453.1:653098-654957:- gene-YOR175C_MUCL30388 rna-NM_001183594.1_MUCL30388 cds-NP_014818.1_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005293.1:647790-649649:- gene-YOR175C_MUCL39482 rna-NM_001183594.1_MUCL39482 cds-NP_014818.1_MUCL39482 99.6 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005437.1:657211-659070:- gene-YOR175C_MUCL42920 rna-NM_001183594.1_MUCL42920 cds-NP_014818.1_MUCL42920 99.9 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011824.1:659704-661563:- gene-YOR175C_NCIM3186 rna-NM_001183594.1_NCIM3186 cds-NP_014818.1_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005277.1:647876-649735:- gene-YOR175C_NCYC1407 rna-NM_001183594.1_NCYC1407 cds-NP_014818.1_NCYC1407 99.6 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994154.1:646387-648246:- gene-YOR175C_PE2H3 rna-NM_001183594.1_PE2H3 cds-NP_014818.1_PE2H3 99.4 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999886.1:656764-658623:- gene-YOR175C_PE2H4 rna-NM_001183594.1_PE2H4 cds-NP_014818.1_PE2H4 99.4 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001147.6:659815-661674:- gene-YOR175C_S288C rna-NM_001183594.1_S288C cds-NP_014818.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000006.1:76373-78232:- gene-YOR175C_SA1 rna-NM_001183594.1_SA1 cds-NP_014818.1_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005501.1:637693-639552:- gene-YOR175C_ThermosaccDry rna-NM_001183594.1_ThermosaccDry cds-NP_014818.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005469.1:701390-703249:- gene-YOR175C_VR1 rna-NM_001183594.1_VR1 cds-NP_014818.1_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000032.1:371144-373003:- gene-YOR175C_ZTW1 rna-NM_001183594.1_ZTW1 cds-NP_014818.1_ZTW1 99.6 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047501.1:642662-644521:- gene-YOR175C_Sparadoxus rna-NM_001183594.1_Sparadoxus cds-NP_014818.1_Sparadoxus 92.3 100.0 Verified 1 1 1 False True False False False

Additional files