Gene name: ALD2
Reference locus (S288C): YMR170C
Gene biotype: protein_coding
Description: Cytoplasmic aldehyde dehydrogenase; involved in ethanol oxidation and beta-alanine biosynthesis; uses NAD+ as the preferred coenzyme; expression is stress induced and glucose repressed; very similar to Ald3p
Top 10 interactors (score): FMS1 (0.973); ACH1 (0.967); AMD2 (0.963); UGA1 (0.961); GAD1 (0.951); PAN6 (0.947); ACS2 (0.946); ACS1 (0.942); POS5 (0.914); TDA10 (0.91); YEF1 (0.905); NIT1 (0.905); UTR1 (0.901); PDC6 (0.901); PDC1 (0.895); ADH2 (0.888); GDH2 (0.878); POX1 (0.877); ADH1 (0.875); SFA1 (0.865)
Homologues (species, bitscore): ALDH1A1 (Homo sapiens, 455.3); Aldh1a2 (Mus musculus, 449.5); aldh2l (Danio rerio, 452.6); aldh1b1 (Xenopus tropicalis, 445.3); Aldh (Drosophila melanogaster, 435.3); alh-1 (Caenorhabditis elegans, 451.8); ALDH2C4 (Arabidopsis thaliana, 431.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:641311-642831:- | gene-YMR170C_AKU4011 | rna-NM_001182674.1_AKU4011 | cds-NP_013893.1_AKU4011 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000068.1:29998-31518:+ | gene-YMR170C_BG1 | rna-NM_001182674.1_BG1 | cds-NP_013893.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:584239-585759:- | gene-YMR170C_Bruggeman | rna-NM_001182674.1_Bruggeman | cds-NP_013893.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:587240-588874:- | gene-YMR170C_CAT1 | rna-NM_001182674.1_CAT1 | cds-NP_013893.1_CAT1 | 92.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:573992-575512:- | gene-YMR170C_CBS1585 | rna-NM_001182674.1_CBS1585 | cds-NP_013893.1_CBS1585 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:577857-579377:- | gene-YMR170C_CBS436 | rna-NM_001182674.1_CBS436 | cds-NP_013893.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:686609-687717:- | gene-YMR170C_CBS6412 | rna-NM_001182674.1_CBS6412 | cds-NP_013893.1_CBS6412 | 72.0 | 72.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:572542-574062:- | gene-YMR170C_CBS6413 | rna-NM_001182674.1_CBS6413 | cds-NP_013893.1_CBS6413 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:596087-597617:- | gene-YMR170C_CENPK1137D | rna-NM_001182674.1_CENPK1137D | cds-NP_013893.1_CENPK1137D | 77.3 | 99.3 | Unannotated | 1 | 1 | 0 | False | False | True | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:634168-635688:- | gene-YMR170C_EthanolRed | rna-NM_001182674.1_EthanolRed | cds-NP_013893.1_EthanolRed | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:579322-580842:- | gene-YMR170C_FaliES1 | rna-NM_001182674.1_FaliES1 | cds-NP_013893.1_FaliES1 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000279.1:1-415:+ | gene-YMR170C_JAY291 | rna-NM_001182674.1_JAY291 | cds-NP_013893.1_JAY291 | 27.1 | 27.2 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:579213-580733:- | gene-YMR170C_MUCL30387 | rna-NM_001182674.1_MUCL30387 | cds-NP_013893.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:574678-576198:- | gene-YMR170C_MUCL39482 | rna-NM_001182674.1_MUCL39482 | cds-NP_013893.1_MUCL39482 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:581506-583009:- | gene-YMR170C_MUCL42920 | rna-NM_001182674.1_MUCL42920 | cds-NP_013893.1_MUCL42920 | 96.4 | 98.4 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:601516-603036:- | gene-YMR170C_NCIM3186 | rna-NM_001182674.1_NCIM3186 | cds-NP_013893.1_NCIM3186 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:574380-575900:- | gene-YMR170C_NCYC1407 | rna-NM_001182674.1_NCYC1407 | cds-NP_013893.1_NCYC1407 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:584722-586242:- | gene-YMR170C_PE2H3 | rna-NM_001182674.1_PE2H3 | cds-NP_013893.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:585184-586704:- | gene-YMR170C_PE2H4 | rna-NM_001182674.1_PE2H4 | cds-NP_013893.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:601562-603082:- | gene-YMR170C_S288C | rna-NM_001182674.1_S288C | cds-NP_013893.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:575054-576574:- | gene-YMR170C_ThermosaccDry | rna-NM_001182674.1_ThermosaccDry | cds-NP_013893.1_ThermosaccDry | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:587962-589725:- | gene-YMR170C_VR1 | rna-NM_001182674.1_VR1 | cds-NP_013893.1_VR1 | 79.1 | 96.1 | Unannotated | 1 | 1 | 0 | False | False | True | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000027.1:549677-551197:- | gene-YMR170C_ZTW1 | rna-NM_001182674.1_ZTW1 | cds-NP_013893.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:593338-594858:- | gene-YMR170C_Sparadoxus | rna-NM_001182674.1_Sparadoxus | cds-NP_013893.1_Sparadoxus | 89.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |