Gene name: AKR1
Reference locus (S288C): YDR264C
Gene biotype: protein_coding
Description: Palmitoyltransferase AKR1; Palmitoyl transferase involved in protein palmitoylation; acts as a negative regulator of pheromone response pathway; required for endocytosis of pheromone receptors; involved in cell shape control; contains ankyrin repeats; AKR1 has a paralog, AKR2, that arose from the whole genome duplication; any of several human homologs encoding DHHC-type zinc fingers (ZDHHC) can complement temperature sensitivity of yeast akr1 null mutant; Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily
Top 10 interactors (score): SWF1 (0.974); PFA3 (0.968); PFA4 (0.962); YCK2 (0.961); STE4 (0.944); SHR5 (0.92); PFA5 (0.902); YCK1 (0.898); YPL199C (0.892); VAC8 (0.875); LCB4 (0.791); STE3 (0.785); MEH1 (0.784); SNA4 (0.76); STE18 (0.759); RAS2 (0.755); ANR2 (0.748); GPA1 (0.747); NMT1 (0.73); ENV7 (0.724)
Homologues (species, bitscore): ZDHHC17 (Homo sapiens, 223.0); Zdhhc17 (Mus musculus, 220.7); zdhhc17 (Danio rerio, 219.2); zdhhc17 (Xenopus tropicalis, 220.7); Hip14 (Drosophila melanogaster, 175.3); H32C10.3 (Caenorhabditis elegans, 131.7); AT2G14255 (Arabidopsis thaliana, 142.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:948322-950616:- | gene-YDR264C_AKU4011 | rna-NM_001180572.1_AKU4011 | cds-NP_010550.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:181712-184006:+ | gene-YDR264C_BG1 | rna-NM_001180572.1_BG1 | cds-NP_010550.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:974495-976789:- | gene-YDR264C_Bruggeman | rna-NM_001180572.1_Bruggeman | cds-NP_010550.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:962337-964631:- | gene-YDR264C_CAT1 | rna-NM_001180572.1_CAT1 | cds-NP_010550.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:942767-945061:- | gene-YDR264C_CBS1585 | rna-NM_001180572.1_CBS1585 | cds-NP_010550.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:960801-963095:- | gene-YDR264C_CBS436 | rna-NM_001180572.1_CBS436 | cds-NP_010550.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:939450-941744:- | gene-YDR264C_CBS6412 | rna-NM_001180572.1_CBS6412 | cds-NP_010550.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:960686-962980:- | gene-YDR264C_CBS6413 | rna-NM_001180572.1_CBS6413 | cds-NP_010550.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:994672-996966:- | gene-YDR264C_CENPK1137D | rna-NM_001180572.1_CENPK1137D | cds-NP_010550.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:946867-949161:- | gene-YDR264C_EthanolRed | rna-NM_001180572.1_EthanolRed | cds-NP_010550.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:955069-957363:- | gene-YDR264C_FaliES1 | rna-NM_001180572.1_FaliES1 | cds-NP_010550.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000176.1:3327-5621:- | gene-YDR264C_JAY291 | rna-NM_001180572.1_JAY291 | cds-NP_010550.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:960131-962425:- | gene-YDR264C_MUCL30387 | rna-NM_001180572.1_MUCL30387 | cds-NP_010550.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:947840-950134:- | gene-YDR264C_MUCL30388 | rna-NM_001180572.1_MUCL30388 | cds-NP_010550.1_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:934573-936867:- | gene-YDR264C_MUCL39482 | rna-NM_001180572.1_MUCL39482 | cds-NP_010550.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:874569-876863:- | gene-YDR264C_MUCL42920 | rna-NM_001180572.1_MUCL42920 | cds-NP_010550.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:995952-998246:- | gene-YDR264C_NCIM3186 | rna-NM_001180572.1_NCIM3186 | cds-NP_010550.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:947863-950157:- | gene-YDR264C_NCYC1407 | rna-NM_001180572.1_NCYC1407 | cds-NP_010550.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:958494-960788:- | gene-YDR264C_PE2H3 | rna-NM_001180572.1_PE2H3 | cds-NP_010550.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:963771-966065:- | gene-YDR264C_PE2H4 | rna-NM_001180572.1_PE2H4 | cds-NP_010550.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:996029-998323:- | gene-YDR264C_S288C | rna-NM_001180572.1_S288C | cds-NP_010550.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000102.1:3651-5945:- | gene-YDR264C_SA1 | rna-NM_001180572.1_SA1 | cds-NP_010550.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:959354-961648:- | gene-YDR264C_ThermosaccDry | rna-NM_001180572.1_ThermosaccDry | cds-NP_010550.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:974950-977244:- | gene-YDR264C_VR1 | rna-NM_001180572.1_VR1 | cds-NP_010550.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:3483-5777:- | gene-YDR264C_ZTW1 | rna-NM_001180572.1_ZTW1 | cds-NP_010550.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:955771-958074:- | gene-YDR264C_Sparadoxus | rna-NM_001180572.1_Sparadoxus | cds-NP_010550.1_Sparadoxus | 90.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |