Gene name: AIR2
Reference locus (S288C): YDL175C
Gene biotype: protein_coding
Description: Protein AIR2; RNA-binding subunit of the TRAMP nuclear RNA surveillance complex; involved in nuclear RNA processing and degradation; involved in TRAMP complex assembly as a bridge between Mtr4p and Trf4p; stimulates the poly(A) polymerase activity of Pap2p in vitro; has 5 zinc knuckle motifs; AIR2 has a paralog, AIR1, that arose from the whole genome duplication; Air2p and Air1p have nonredundant roles in regulation of substrate specificity of the exosome
Top 10 interactors (score): TRF5 (0.999); MTR4 (0.999); PAP2 (0.999); AIR1 (0.988); RRP6 (0.986); NAB3 (0.971); DIS3 (0.946); DHR2 (0.936); SEN1 (0.93); PAP1 (0.922); SKI2 (0.896); LRP1 (0.835); XRN1 (0.827); NRD1 (0.807); SKI3 (0.805); RRP40 (0.803); RAT1 (0.802); SKI6 (0.77); SKI8 (0.767); CSL4 (0.747)
Homologues (species, bitscore): ZCCHC7 (Homo sapiens, 61.6); Zcchc7 (Mus musculus, 66.6); zcchc7 (Danio rerio, 79.0); zcchc7 (Xenopus tropicalis, 71.2); CG9715 (Drosophila melanogaster, 58.9); glh-4 (Caenorhabditis elegans, 50.1); AT3G43590 (Arabidopsis thaliana, 51.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:128910-129944:- | gene-YDL175C_AKU4011 | rna-NM_001180235.1_AKU4011 | cds-NP_010106.1_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000102.1:419768-420802:+ | gene-YDL175C_BG1 | rna-NM_001180235.1_BG1 | cds-NP_010106.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:144965-145999:- | gene-YDL175C_Bruggeman | rna-NM_001180235.1_Bruggeman | cds-NP_010106.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:143291-144325:- | gene-YDL175C_CAT1 | rna-NM_001180235.1_CAT1 | cds-NP_010106.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:126948-127982:- | gene-YDL175C_CBS1585 | rna-NM_001180235.1_CBS1585 | cds-NP_010106.1_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:143906-144940:- | gene-YDL175C_CBS436 | rna-NM_001180235.1_CBS436 | cds-NP_010106.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:126511-127545:- | gene-YDL175C_CBS6412 | rna-NM_001180235.1_CBS6412 | cds-NP_010106.1_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:145322-146356:- | gene-YDL175C_CBS6413 | rna-NM_001180235.1_CBS6413 | cds-NP_010106.1_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:143157-144191:- | gene-YDL175C_CENPK1137D | rna-NM_001180235.1_CENPK1137D | cds-NP_010106.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:140330-141364:- | gene-YDL175C_EthanolRed | rna-NM_001180235.1_EthanolRed | cds-NP_010106.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:145656-146690:- | gene-YDL175C_FaliES1 | rna-NM_001180235.1_FaliES1 | cds-NP_010106.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000032.1:72822-73856:+ | gene-YDL175C_JAY291 | rna-NM_001180235.1_JAY291 | cds-NP_010106.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:143267-144301:- | gene-YDL175C_MUCL30387 | rna-NM_001180235.1_MUCL30387 | cds-NP_010106.1_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:134916-135950:- | gene-YDL175C_MUCL30388 | rna-NM_001180235.1_MUCL30388 | cds-NP_010106.1_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:128090-129124:- | gene-YDL175C_MUCL39482 | rna-NM_001180235.1_MUCL39482 | cds-NP_010106.1_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | MBVV01000307.1:40245-41279:+ | gene-YDL175C_MUCL42920 | rna-NM_001180235.1_MUCL42920 | cds-NP_010106.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:144407-145441:- | gene-YDL175C_NCIM3186 | rna-NM_001180235.1_NCIM3186 | cds-NP_010106.1_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:127979-129013:- | gene-YDL175C_NCYC1407 | rna-NM_001180235.1_NCYC1407 | cds-NP_010106.1_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:135287-136321:- | gene-YDL175C_PE2H3 | rna-NM_001180235.1_PE2H3 | cds-NP_010106.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:135291-136325:- | gene-YDL175C_PE2H4 | rna-NM_001180235.1_PE2H4 | cds-NP_010106.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:144484-145518:- | gene-YDL175C_S288C | rna-NM_001180235.1_S288C | cds-NP_010106.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000043.1:10064-11098:- | gene-YDL175C_SA1 | rna-NM_001180235.1_SA1 | cds-NP_010106.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:145416-146450:- | gene-YDL175C_ThermosaccDry | rna-NM_001180235.1_ThermosaccDry | cds-NP_010106.1_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:146058-147092:- | gene-YDL175C_VR1 | rna-NM_001180235.1_VR1 | cds-NP_010106.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:143590-144624:- | gene-YDL175C_ZTW1 | rna-NM_001180235.1_ZTW1 | cds-NP_010106.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:145806-146834:- | gene-YDL175C_Sparadoxus | rna-NM_001180235.1_Sparadoxus | cds-NP_010106.1_Sparadoxus | 91.1 | 99.1 | Verified | 1 | 1 | 1 | False | True | False | False | False |