AIR2 (YDL175C)


Gene profile

Gene name: AIR2
Reference locus (S288C): YDL175C
Gene biotype: protein_coding

Description: Protein AIR2; RNA-binding subunit of the TRAMP nuclear RNA surveillance complex; involved in nuclear RNA processing and degradation; involved in TRAMP complex assembly as a bridge between Mtr4p and Trf4p; stimulates the poly(A) polymerase activity of Pap2p in vitro; has 5 zinc knuckle motifs; AIR2 has a paralog, AIR1, that arose from the whole genome duplication; Air2p and Air1p have nonredundant roles in regulation of substrate specificity of the exosome

Top 10 interactors (score): TRF5 (0.999); MTR4 (0.999); PAP2 (0.999); AIR1 (0.988); RRP6 (0.986); NAB3 (0.971); DIS3 (0.946); DHR2 (0.936); SEN1 (0.93); PAP1 (0.922); SKI2 (0.896); LRP1 (0.835); XRN1 (0.827); NRD1 (0.807); SKI3 (0.805); RRP40 (0.803); RAT1 (0.802); SKI6 (0.77); SKI8 (0.767); CSL4 (0.747)

Homologues (species, bitscore): ZCCHC7 (Homo sapiens, 61.6); Zcchc7 (Mus musculus, 66.6); zcchc7 (Danio rerio, 79.0); zcchc7 (Xenopus tropicalis, 71.2); CG9715 (Drosophila melanogaster, 58.9); glh-4 (Caenorhabditis elegans, 50.1); AT3G43590 (Arabidopsis thaliana, 51.6)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:128910-129944:- gene-YDL175C_AKU4011 rna-NM_001180235.1_AKU4011 cds-NP_010106.1_AKU4011 100.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000102.1:419768-420802:+ gene-YDL175C_BG1 rna-NM_001180235.1_BG1 cds-NP_010106.1_BG1 99.8 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:144965-145999:- gene-YDL175C_Bruggeman rna-NM_001180235.1_Bruggeman cds-NP_010106.1_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:143291-144325:- gene-YDL175C_CAT1 rna-NM_001180235.1_CAT1 cds-NP_010106.1_CAT1 99.9 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:126948-127982:- gene-YDL175C_CBS1585 rna-NM_001180235.1_CBS1585 cds-NP_010106.1_CBS1585 100.0 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:143906-144940:- gene-YDL175C_CBS436 rna-NM_001180235.1_CBS436 cds-NP_010106.1_CBS436 99.9 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:126511-127545:- gene-YDL175C_CBS6412 rna-NM_001180235.1_CBS6412 cds-NP_010106.1_CBS6412 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:145322-146356:- gene-YDL175C_CBS6413 rna-NM_001180235.1_CBS6413 cds-NP_010106.1_CBS6413 100.0 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:143157-144191:- gene-YDL175C_CENPK1137D rna-NM_001180235.1_CENPK1137D cds-NP_010106.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:140330-141364:- gene-YDL175C_EthanolRed rna-NM_001180235.1_EthanolRed cds-NP_010106.1_EthanolRed 100.0 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:145656-146690:- gene-YDL175C_FaliES1 rna-NM_001180235.1_FaliES1 cds-NP_010106.1_FaliES1 100.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000032.1:72822-73856:+ gene-YDL175C_JAY291 rna-NM_001180235.1_JAY291 cds-NP_010106.1_JAY291 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:143267-144301:- gene-YDL175C_MUCL30387 rna-NM_001180235.1_MUCL30387 cds-NP_010106.1_MUCL30387 99.9 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:134916-135950:- gene-YDL175C_MUCL30388 rna-NM_001180235.1_MUCL30388 cds-NP_010106.1_MUCL30388 99.9 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:128090-129124:- gene-YDL175C_MUCL39482 rna-NM_001180235.1_MUCL39482 cds-NP_010106.1_MUCL39482 100.0 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe MBVV01000307.1:40245-41279:+ gene-YDL175C_MUCL42920 rna-NM_001180235.1_MUCL42920 cds-NP_010106.1_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:144407-145441:- gene-YDL175C_NCIM3186 rna-NM_001180235.1_NCIM3186 cds-NP_010106.1_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:127979-129013:- gene-YDL175C_NCYC1407 rna-NM_001180235.1_NCYC1407 cds-NP_010106.1_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:135287-136321:- gene-YDL175C_PE2H3 rna-NM_001180235.1_PE2H3 cds-NP_010106.1_PE2H3 99.8 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:135291-136325:- gene-YDL175C_PE2H4 rna-NM_001180235.1_PE2H4 cds-NP_010106.1_PE2H4 99.8 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:144484-145518:- gene-YDL175C_S288C rna-NM_001180235.1_S288C cds-NP_010106.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000043.1:10064-11098:- gene-YDL175C_SA1 rna-NM_001180235.1_SA1 cds-NP_010106.1_SA1 99.8 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:145416-146450:- gene-YDL175C_ThermosaccDry rna-NM_001180235.1_ThermosaccDry cds-NP_010106.1_ThermosaccDry 100.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:146058-147092:- gene-YDL175C_VR1 rna-NM_001180235.1_VR1 cds-NP_010106.1_VR1 99.8 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000006.1:143590-144624:- gene-YDL175C_ZTW1 rna-NM_001180235.1_ZTW1 cds-NP_010106.1_ZTW1 100.0 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:145806-146834:- gene-YDL175C_Sparadoxus rna-NM_001180235.1_Sparadoxus cds-NP_010106.1_Sparadoxus 91.1 99.1 Verified 1 1 1 False True False False False

Additional files