Gene name: AIP1
Reference locus (S288C): YMR092C
Gene biotype: protein_coding
Description: Actin-interacting protein 1; Actin cortical patch component; interacts with the actin depolymerizing factor cofilin; inhibits elongation of aged ADP-actin filaments decorated with cofilin to maintain a high level of assembly-competent actin species; required to restrict cofilin localization to cortical patches; putative regulator of cytokinesis; contains WD repeats; protein increases in abundance and relocalizes from cytoplasm to plasma membrane upon DNA replication stress
Top 10 interactors (score): COF1 (0.999); ACT1 (0.992); SRV2 (0.97); CAP2 (0.958); CRN1 (0.955); ARP2 (0.954); TPM2 (0.934); TPM1 (0.932); PFY1 (0.931); AIM7 (0.921); SAC6 (0.915); TWF1 (0.9); CAP1 (0.85); PRM15 (0.836); ABP1 (0.818); BNR1 (0.799); RVS167 (0.766); MRX9 (0.717); BNI1 (0.714); LDB17 (0.696)
Homologues (species, bitscore): WDR1 (Homo sapiens, 250.0); Wdr1 (Mus musculus, 256.9); WDR1 (Danio rerio, 200.3); wdr1 (Xenopus tropicalis, 197.6); flr (Drosophila melanogaster, 257.7); unc-78 (Caenorhabditis elegans, 252.7); AT2G01330 (Arabidopsis thaliana, 263.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:489569-491416:- | gene-YMR092C_AKU4011 | rna-NM_001182592.1_AKU4011 | cds-NP_013810.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000201.1:51594-53441:+ | gene-YMR092C_BG1 | rna-NM_001182592.1_BG1 | cds-NP_013810.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:431997-433844:- | gene-YMR092C_Bruggeman | rna-NM_001182592.1_Bruggeman | cds-NP_013810.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:432320-434167:- | gene-YMR092C_CAT1 | rna-NM_001182592.1_CAT1 | cds-NP_013810.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:422512-424359:- | gene-YMR092C_CBS1585 | rna-NM_001182592.1_CBS1585 | cds-NP_013810.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:427836-429683:- | gene-YMR092C_CBS436 | rna-NM_001182592.1_CBS436 | cds-NP_013810.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:535608-537455:- | gene-YMR092C_CBS6412 | rna-NM_001182592.1_CBS6412 | cds-NP_013810.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:421769-423616:- | gene-YMR092C_CBS6413 | rna-NM_001182592.1_CBS6413 | cds-NP_013810.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:445739-447586:- | gene-YMR092C_CENPK1137D | rna-NM_001182592.1_CENPK1137D | cds-NP_013810.1_CENPK1137D | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005483.1:422403-424250:- | gene-YMR092C_EthanolRed | rna-NM_001182592.1_EthanolRed | cds-NP_013810.1_EthanolRed | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:425569-427416:- | gene-YMR092C_FaliES1 | rna-NM_001182592.1_FaliES1 | cds-NP_013810.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000033.1:9798-11645:+ | gene-YMR092C_JAY291 | rna-NM_001182592.1_JAY291 | cds-NP_013810.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:428928-430775:- | gene-YMR092C_MUCL30387 | rna-NM_001182592.1_MUCL30387 | cds-NP_013810.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:432914-434761:- | gene-YMR092C_MUCL30388 | rna-NM_001182592.1_MUCL30388 | cds-NP_013810.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:422821-424668:- | gene-YMR092C_MUCL39482 | rna-NM_001182592.1_MUCL39482 | cds-NP_013810.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:429486-431333:- | gene-YMR092C_MUCL42920 | rna-NM_001182592.1_MUCL42920 | cds-NP_013810.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:451586-453433:- | gene-YMR092C_NCIM3186 | rna-NM_001182592.1_NCIM3186 | cds-NP_013810.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:422714-424561:- | gene-YMR092C_NCYC1407 | rna-NM_001182592.1_NCYC1407 | cds-NP_013810.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:428434-430281:- | gene-YMR092C_PE2H3 | rna-NM_001182592.1_PE2H3 | cds-NP_013810.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:434529-436376:- | gene-YMR092C_PE2H4 | rna-NM_001182592.1_PE2H4 | cds-NP_013810.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:451632-453479:- | gene-YMR092C_S288C | rna-NM_001182592.1_S288C | cds-NP_013810.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000005.1:96688-98535:+ | gene-YMR092C_SA1 | rna-NM_001182592.1_SA1 | cds-NP_013810.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:423372-425219:- | gene-YMR092C_ThermosaccDry | rna-NM_001182592.1_ThermosaccDry | cds-NP_013810.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:435020-436867:- | gene-YMR092C_VR1 | rna-NM_001182592.1_VR1 | cds-NP_013810.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000027.1:399643-401490:- | gene-YMR092C_ZTW1 | rna-NM_001182592.1_ZTW1 | cds-NP_013810.1_ZTW1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:436086-437935:- | gene-YMR092C_Sparadoxus | rna-NM_001182592.1_Sparadoxus | cds-NP_013810.1_Sparadoxus | 89.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |