AIM45 (YPR004C)


Gene profile

Gene name: AIM45
Reference locus (S288C): YPR004C
Gene biotype: protein_coding

Description: Probable electron transfer flavoprotein subunit alpha, mitochondrial; Putative ortholog of mammalian ETF-alpha; interacts with frataxin, Yfh1p; null mutant displays elevated frequency of mitochondrial genome loss; may have a role in oxidative stress response; ETF-alpha is an electron transfer flavoprotein complex subunit

Top 10 interactors (score): CIR2 (0.999); CIR1 (0.999); POX1 (0.987); HSP10 (0.981); MXR1 (0.967); ATX1 (0.962); COX17 (0.962); MDH1 (0.893); ATP1 (0.863); MDH3 (0.857); SDH2 (0.826); MDH2 (0.814); DLD1 (0.806); YFH1 (0.754); LPD1 (0.754); NDE2 (0.747); NDI1 (0.744); MTO1 (0.722); QCR2 (0.71); FAD1 (0.708)

Homologues (species, bitscore): ETFA (Homo sapiens, 290.0); Etfa (Mus musculus, 281.2); etfa (Danio rerio, 285.0); etfa (Xenopus tropicalis, 280.0); wal (Drosophila melanogaster, 260.0); F27D4.1 (Caenorhabditis elegans, 263.8); ETFALPHA (Arabidopsis thaliana, 250.0)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005310.1:535629-536662:- gene-YPR004C_AKU4011 rna-NM_001184101.1_AKU4011 cds-NP_015329.1_AKU4011 99.3 99.9 Verified 1 1 0 False False False True False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000091.1:360522-361556:+ gene-YPR004C_BG1 rna-NM_001184101.1_BG1 cds-NP_015329.1_BG1 99.6 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005518.1:612643-613677:- gene-YPR004C_Bruggeman rna-NM_001184101.1_Bruggeman cds-NP_015329.1_Bruggeman 99.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005534.1:655749-656783:- gene-YPR004C_CAT1 rna-NM_001184101.1_CAT1 cds-NP_015329.1_CAT1 99.8 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005374.1:539316-540349:- gene-YPR004C_CBS1585 rna-NM_001184101.1_CBS1585 cds-NP_015329.1_CBS1585 99.3 99.9 Verified 1 1 0 False False False True False
CBS436 GCA_001738355.1 Sake Asia CM005358.1:553730-554764:- gene-YPR004C_CBS436 rna-NM_001184101.1_CBS436 cds-NP_015329.1_CBS436 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005342.1:543065-544098:- gene-YPR004C_CBS6412 rna-NM_001184101.1_CBS6412 cds-NP_015329.1_CBS6412 99.3 99.9 Mismatch 1 1 0 False False False True False
CBS6413 GCA_001738265.1 Sake Asia CM005326.1:535776-536809:- gene-YPR004C_CBS6413 rna-NM_001184101.1_CBS6413 cds-NP_015329.1_CBS6413 99.3 99.9 Verified 1 1 0 False False False True False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001537.1:563982-565016:- gene-YPR004C_CENPK1137D rna-NM_001184101.1_CENPK1137D cds-NP_015329.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:533563-534596:- gene-YPR004C_EthanolRed rna-NM_001184101.1_EthanolRed cds-NP_015329.1_EthanolRed 99.4 99.9 Verified 1 1 0 False False False True False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005550.1:541393-542426:- gene-YPR004C_FaliES1 rna-NM_001184101.1_FaliES1 cds-NP_015329.1_FaliES1 99.4 99.9 Verified 1 1 0 False False False True False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000337.1:3225-4259:- gene-YPR004C_JAY291 rna-NM_001184101.1_JAY291 cds-NP_015329.1_JAY291 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005422.1:553854-554888:- gene-YPR004C_MUCL30387 rna-NM_001184101.1_MUCL30387 cds-NP_015329.1_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005454.1:552956-553990:- gene-YPR004C_MUCL30388 rna-NM_001184101.1_MUCL30388 cds-NP_015329.1_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005294.1:532556-533589:- gene-YPR004C_MUCL39482 rna-NM_001184101.1_MUCL39482 cds-NP_015329.1_MUCL39482 99.3 99.9 Verified 1 1 0 False False False True False
MUCL42920 GCA_001738485.1 Bread Europe CM005438.1:592739-593772:- gene-YPR004C_MUCL42920 rna-NM_001184101.1_MUCL42920 cds-NP_015329.1_MUCL42920 99.8 99.9 Verified 1 1 0 False False False True False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011825.1:563990-565024:- gene-YPR004C_NCIM3186 rna-NM_001184101.1_NCIM3186 cds-NP_015329.1_NCIM3186 99.0 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005278.1:540255-541288:- gene-YPR004C_NCYC1407 rna-NM_001184101.1_NCYC1407 cds-NP_015329.1_NCYC1407 99.3 99.9 Verified 1 1 0 False False False True False
PE2H3 GCA_905220325.1 Bioethanol South America HG994155.1:547185-548219:- gene-YPR004C_PE2H3 rna-NM_001184101.1_PE2H3 cds-NP_015329.1_PE2H3 99.6 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999887.1:546800-547834:- gene-YPR004C_PE2H4 rna-NM_001184101.1_PE2H4 cds-NP_015329.1_PE2H4 99.6 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001148.4:564007-565041:- gene-YPR004C_S288C rna-NM_001184101.1_S288C cds-NP_015329.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000026.1:135249-136283:+ gene-YPR004C_SA1 rna-NM_001184101.1_SA1 cds-NP_015329.1_SA1 99.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005502.1:541192-542225:- gene-YPR004C_ThermosaccDry rna-NM_001184101.1_ThermosaccDry cds-NP_015329.1_ThermosaccDry 99.3 99.9 Verified 1 1 0 False False False True False
VR1 GCA_001738595.1 Bioethanol South America CM005470.1:557439-558473:- gene-YPR004C_VR1 rna-NM_001184101.1_VR1 cds-NP_015329.1_VR1 99.6 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000033.1:540497-541530:- gene-YPR004C_ZTW1 rna-NM_001184101.1_ZTW1 cds-NP_015329.1_ZTW1 99.5 99.9 Verified 1 1 0 False False False True False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047502.1:540100-541134:- gene-YPR004C_Sparadoxus rna-NM_001184101.1_Sparadoxus cds-NP_015329.1_Sparadoxus 90.6 100.0 Unannotated 1 1 0 False False False False True

Additional files