Gene name: AIM44
Reference locus (S288C): YPL158C
Gene biotype: protein_coding
Description: Altered inheritance of mitochondria protein 44; Protein that regulates Cdc42p and Rho1p; functions in the late steps of cytokinesis and cell separation; sustains Rho1p at the cell division site after actomyosin ring contraction; inhibits the activation of Cdc42-Cla4 at the cell division site to prevent budding inside the old bud neck; transcription is regulated by Swi5p; null mutant displays elevated frequency of mitochondrial genome loss; relocalizes from bud neck to cytoplasm upon DNA replication stress
Top 10 interactors (score): NBA1 (0.947); NIS1 (0.92); HOF1 (0.867); NAP1 (0.853); CDC42 (0.784); RAX1 (0.778); RHO1 (0.75); KCH1 (0.71); PBI1 (0.692); FKS1 (0.685); CYK3 (0.659); PXL1 (0.656); BUD4 (0.652); SWI5 (0.651); SHS1 (0.616); EPO1 (0.576); YPR174C (0.575); KXD1 (0.574); MYO1 (0.573); RSR1 (0.565)
Homologues (species, bitscore): LAS1L (Homo sapiens, 56.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:229699-231966:- | gene-YPL158C_AKU4011 | rna-NM_001183972.1_AKU4011 | cds-NP_015167.1_AKU4011 | 98.0 | 99.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000069.1:435366-437642:- | gene-YPL158C_BG1 | rna-NM_001183972.1_BG1 | cds-NP_015167.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:255690-257957:- | gene-YPL158C_Bruggeman | rna-NM_001183972.1_Bruggeman | cds-NP_015167.1_Bruggeman | 98.1 | 99.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:252355-254631:- | gene-YPL158C_CAT1 | rna-NM_001183972.1_CAT1 | cds-NP_015167.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:233762-236029:- | gene-YPL158C_CBS1585 | rna-NM_001183972.1_CBS1585 | cds-NP_015167.1_CBS1585 | 98.0 | 99.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:248418-250694:- | gene-YPL158C_CBS436 | rna-NM_001183972.1_CBS436 | cds-NP_015167.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:238440-240707:- | gene-YPL158C_CBS6412 | rna-NM_001183972.1_CBS6412 | cds-NP_015167.1_CBS6412 | 98.0 | 99.4 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:230402-232669:- | gene-YPL158C_CBS6413 | rna-NM_001183972.1_CBS6413 | cds-NP_015167.1_CBS6413 | 98.0 | 99.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:251918-254194:- | gene-YPL158C_CENPK1137D | rna-NM_001183972.1_CENPK1137D | cds-NP_015167.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:228429-230654:- | gene-YPL158C_EthanolRed | rna-NM_001183972.1_EthanolRed | cds-NP_015167.1_EthanolRed | 96.5 | 97.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:236021-238246:- | gene-YPL158C_FaliES1 | rna-NM_001183972.1_FaliES1 | cds-NP_015167.1_FaliES1 | 96.6 | 97.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000007.1:127601-129878:+ | gene-YPL158C_JAY291 | rna-NM_001183972.1_JAY291 | cds-NP_015167.1_JAY291 | 99.5 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:246932-249199:- | gene-YPL158C_MUCL30387 | rna-NM_001183972.1_MUCL30387 | cds-NP_015167.1_MUCL30387 | 98.1 | 99.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:244949-247216:- | gene-YPL158C_MUCL30388 | rna-NM_001183972.1_MUCL30388 | cds-NP_015167.1_MUCL30388 | 98.1 | 99.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:227091-229358:- | gene-YPL158C_MUCL39482 | rna-NM_001183972.1_MUCL39482 | cds-NP_015167.1_MUCL39482 | 98.0 | 99.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:283819-286086:- | gene-YPL158C_MUCL42920 | rna-NM_001183972.1_MUCL42920 | cds-NP_015167.1_MUCL42920 | 98.4 | 99.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:252017-254293:- | gene-YPL158C_NCIM3186 | rna-NM_001183972.1_NCIM3186 | cds-NP_015167.1_NCIM3186 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:233554-235821:- | gene-YPL158C_NCYC1407 | rna-NM_001183972.1_NCYC1407 | cds-NP_015167.1_NCYC1407 | 98.0 | 99.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:240980-243256:- | gene-YPL158C_PE2H3 | rna-NM_001183972.1_PE2H3 | cds-NP_015167.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:240623-242899:- | gene-YPL158C_PE2H4 | rna-NM_001183972.1_PE2H4 | cds-NP_015167.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:252034-254310:- | gene-YPL158C_S288C | rna-NM_001183972.1_S288C | cds-NP_015167.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000012.1:119376-121652:+ | gene-YPL158C_SA1 | rna-NM_001183972.1_SA1 | cds-NP_015167.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:235819-238044:- | gene-YPL158C_ThermosaccDry | rna-NM_001183972.1_ThermosaccDry | cds-NP_015167.1_ThermosaccDry | 96.6 | 97.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:250751-253027:- | gene-YPL158C_VR1 | rna-NM_001183972.1_VR1 | cds-NP_015167.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:235148-237373:- | gene-YPL158C_ZTW1 | rna-NM_001183972.1_ZTW1 | cds-NP_015167.1_ZTW1 | 96.6 | 97.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:236741-238984:- | gene-YPL158C_Sparadoxus | rna-NM_001183972.1_Sparadoxus | cds-NP_015167.1_Sparadoxus | 84.7 | 98.1 | Verified | 1 | 1 | 1 | False | True | False | False | False |