Gene name: AIM25
Reference locus (S288C): YJR100C
Gene biotype: protein_coding
Description: Altered inheritance rate of mitochondria protein 25; Mitochondria protein of unknown function; interacts genetically with TOR1 to regulate chronological lifespan, and the response to both heat shock and oxidative stress; involved in maintaining the integrity of the mitochondrial network; negative regulator of mitophagy flux; non-tagged protein is detected in purified mitochondria in high-throughput studies; null mutant is viable and displays an elevated frequency of mitochondrial genome loss; similar to murine NOR1
Top 10 interactors (score): CSC1 (0.811); MRPL44 (0.714); SEN54 (0.71); PHM7 (0.691); SLM3 (0.685); PUF3 (0.673); OAR1 (0.645); MRP21 (0.633); MAM33 (0.619); FMP30 (0.617); MTG1 (0.617); ECT1 (0.616); ILM1 (0.613); ATG21 (0.593); RSN1 (0.583); CLD1 (0.572); DRS2 (0.571); PET54 (0.568); KTI11 (0.554); CRD1 (0.535)
Homologues (species, bitscore): PLSCR1 (Homo sapiens, 68.6); mCG_17678 (Mus musculus, 72.4); si:ch73-206p6.1 (Danio rerio, 73.6); plscr2 (Xenopus tropicalis, 73.2); scramb1 (Drosophila melanogaster, 69.3); scrm-8 (Caenorhabditis elegans, 61.6); AT2G04940 (Arabidopsis thaliana, 151.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005304.1:587849-588832:- | gene-YJR100C_AKU4011 | rna-NM_001181758.3_AKU4011 | cds-NP_012634.3_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000190.1:18740-19723:+ | gene-YJR100C_BG1 | rna-NM_001181758.3_BG1 | cds-NP_012634.3_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005512.1:603582-604565:- | gene-YJR100C_Bruggeman | rna-NM_001181758.3_Bruggeman | cds-NP_012634.3_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005528.1:606001-606984:- | gene-YJR100C_CAT1 | rna-NM_001181758.3_CAT1 | cds-NP_012634.3_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005368.1:599914-600897:- | gene-YJR100C_CBS1585 | rna-NM_001181758.3_CBS1585 | cds-NP_012634.3_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005352.1:618021-619004:- | gene-YJR100C_CBS436 | rna-NM_001181758.3_CBS436 | cds-NP_012634.3_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005336.1:587061-588044:- | gene-YJR100C_CBS6412 | rna-NM_001181758.3_CBS6412 | cds-NP_012634.3_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005320.1:589322-590305:- | gene-YJR100C_CBS6413 | rna-NM_001181758.3_CBS6413 | cds-NP_012634.3_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001531.1:598667-599650:- | gene-YJR100C_CENPK1137D | rna-NM_001181758.3_CENPK1137D | cds-NP_012634.3_CENPK1137D | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005480.1:592266-593249:- | gene-YJR100C_EthanolRed | rna-NM_001181758.3_EthanolRed | cds-NP_012634.3_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005544.1:603732-604715:- | gene-YJR100C_FaliES1 | rna-NM_001181758.3_FaliES1 | cds-NP_012634.3_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000054.1:84702-85685:+ | gene-YJR100C_JAY291 | rna-NM_001181758.3_JAY291 | cds-NP_012634.3_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005416.1:601886-602869:- | gene-YJR100C_MUCL30387 | rna-NM_001181758.3_MUCL30387 | cds-NP_012634.3_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005448.1:599198-600181:- | gene-YJR100C_MUCL30388 | rna-NM_001181758.3_MUCL30388 | cds-NP_012634.3_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005288.1:593373-594356:- | gene-YJR100C_MUCL39482 | rna-NM_001181758.3_MUCL39482 | cds-NP_012634.3_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005432.1:597628-598611:- | gene-YJR100C_MUCL42920 | rna-NM_001181758.3_MUCL42920 | cds-NP_012634.3_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011819.1:616330-617313:- | gene-YJR100C_NCIM3186 | rna-NM_001181758.3_NCIM3186 | cds-NP_012634.3_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005272.1:590940-591923:- | gene-YJR100C_NCYC1407 | rna-NM_001181758.3_NCYC1407 | cds-NP_012634.3_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994149.1:608833-609816:- | gene-YJR100C_PE2H3 | rna-NM_001181758.3_PE2H3 | cds-NP_012634.3_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999881.1:602522-603505:- | gene-YJR100C_PE2H4 | rna-NM_001181758.3_PE2H4 | cds-NP_012634.3_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001142.9:616351-617334:- | gene-YJR100C_S288C | rna-NM_001181758.3_S288C | cds-NP_012634.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000038.1:74921-75904:- | gene-YJR100C_SA1 | rna-NM_001181758.3_SA1 | cds-NP_012634.3_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005496.1:597666-598649:- | gene-YJR100C_ThermosaccDry | rna-NM_001181758.3_ThermosaccDry | cds-NP_012634.3_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005464.1:599793-600776:- | gene-YJR100C_VR1 | rna-NM_001181758.3_VR1 | cds-NP_012634.3_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000021.1:577033-578016:- | gene-YJR100C_ZTW1 | rna-NM_001181758.3_ZTW1 | cds-NP_012634.3_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047496.1:610521-611504:- | gene-YJR100C_Sparadoxus | rna-NM_001181758.3_Sparadoxus | cds-NP_012634.3_Sparadoxus | 87.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |