AIM22 (YJL046W)


Gene profile

Gene name: AIM22
Reference locus (S288C): YJL046W
Gene biotype: protein_coding

Description: Octanoyl-coa:protein transferase; Putative lipoate-protein ligase; required along with Lip2 and Lip5 for lipoylation of Lat1p and Kgd2p; similar to E. coli LplA; null mutant displays reduced frequency of mitochondrial genome loss; Belongs to the LplA family

Top 10 interactors (score): GCV3 (0.998); LIP5 (0.997); LIP2 (0.992); KGD2 (0.978); LPD1 (0.975); LAT1 (0.97); PDB1 (0.96); KGD1 (0.927); PDA1 (0.924); HTD2 (0.907); PDX1 (0.854); COA3 (0.838); RRG7 (0.767); PUF3 (0.763); RRG8 (0.76); GEP5 (0.75); RRG9 (0.747); AEP2 (0.744); CEM1 (0.714); EMP65 (0.707)

Homologues (species, bitscore): LIPT1 (Homo sapiens, 139.4); Lipt1 (Mus musculus, 136.3); lipt1 (Danio rerio, 135.2); lipt1 (Xenopus tropicalis, 117.9); DmelCG44243 (Drosophila melanogaster, 107.8); C45G3.3 (Caenorhabditis elegans, 122.5)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005304.1:335196-336425:+ gene-YJL046W_AKU4011 rna-NM_001181479.1_AKU4011 cds-NP_012489.2_AKU4011 100.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000190.1:277368-278597:- gene-YJL046W_BG1 rna-NM_001181479.1_BG1 cds-NP_012489.2_BG1 99.4 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005512.1:347776-349005:+ gene-YJL046W_Bruggeman rna-NM_001181479.1_Bruggeman cds-NP_012489.2_Bruggeman 99.7 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005528.1:353011-354240:+ gene-YJL046W_CAT1 rna-NM_001181479.1_CAT1 cds-NP_012489.2_CAT1 99.5 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005368.1:346850-348079:+ gene-YJL046W_CBS1585 rna-NM_001181479.1_CBS1585 cds-NP_012489.2_CBS1585 100.0 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005352.1:364901-366130:+ gene-YJL046W_CBS436 rna-NM_001181479.1_CBS436 cds-NP_012489.2_CBS436 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005336.1:335955-337184:+ gene-YJL046W_CBS6412 rna-NM_001181479.1_CBS6412 cds-NP_012489.2_CBS6412 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005320.1:337302-338531:+ gene-YJL046W_CBS6413 rna-NM_001181479.1_CBS6413 cds-NP_012489.2_CBS6413 100.0 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001531.1:334850-336079:+ gene-YJL046W_CENPK1137D rna-NM_001181479.1_CENPK1137D cds-NP_012489.2_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005480.1:339034-340263:+ gene-YJL046W_EthanolRed rna-NM_001181479.1_EthanolRed cds-NP_012489.2_EthanolRed 99.7 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005544.1:350608-351837:+ gene-YJL046W_FaliES1 rna-NM_001181479.1_FaliES1 cds-NP_012489.2_FaliES1 99.7 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000210.1:1059-2288:- gene-YJL046W_JAY291 rna-NM_001181479.1_JAY291 cds-NP_012489.2_JAY291 99.7 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005416.1:348930-350159:+ gene-YJL046W_MUCL30387 rna-NM_001181479.1_MUCL30387 cds-NP_012489.2_MUCL30387 99.6 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005448.1:344971-346200:+ gene-YJL046W_MUCL30388 rna-NM_001181479.1_MUCL30388 cds-NP_012489.2_MUCL30388 99.7 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005288.1:339604-340833:+ gene-YJL046W_MUCL39482 rna-NM_001181479.1_MUCL39482 cds-NP_012489.2_MUCL39482 100.0 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005432.1:346298-347527:+ gene-YJL046W_MUCL42920 rna-NM_001181479.1_MUCL42920 cds-NP_012489.2_MUCL42920 99.7 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011819.1:352365-353594:+ gene-YJL046W_NCIM3186 rna-NM_001181479.1_NCIM3186 cds-NP_012489.2_NCIM3186 99.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005272.1:338300-339529:+ gene-YJL046W_NCYC1407 rna-NM_001181479.1_NCYC1407 cds-NP_012489.2_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994149.1:350698-351927:+ gene-YJL046W_PE2H3 rna-NM_001181479.1_PE2H3 cds-NP_012489.2_PE2H3 99.7 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999881.1:350343-351572:+ gene-YJL046W_PE2H4 rna-NM_001181479.1_PE2H4 cds-NP_012489.2_PE2H4 99.7 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001142.9:352386-353615:+ gene-YJL046W_S288C rna-NM_001181479.1_S288C cds-NP_012489.2_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000003.1:148259-149488:+ gene-YJL046W_SA1 rna-NM_001181479.1_SA1 cds-NP_012489.2_SA1 99.3 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005496.1:344021-345250:+ gene-YJL046W_ThermosaccDry rna-NM_001181479.1_ThermosaccDry cds-NP_012489.2_ThermosaccDry 99.7 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005464.1:346513-347742:+ gene-YJL046W_VR1 rna-NM_001181479.1_VR1 cds-NP_012489.2_VR1 99.6 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000021.1:325398-326627:+ gene-YJL046W_ZTW1 rna-NM_001181479.1_ZTW1 cds-NP_012489.2_ZTW1 99.9 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047496.1:349466-350698:+ gene-YJL046W_Sparadoxus rna-NM_001181479.1_Sparadoxus cds-NP_012489.2_Sparadoxus 86.1 99.6 Verified 1 1 1 False True False False False

Additional files