Gene name: AIM14
Reference locus (S288C): YGL160W
Gene biotype: protein_coding
Description: Probable metalloreductase AIM14; NADPH oxidase localized to the perinuclear ER; produces superoxide from NADPH; overexpression causes MCA1 dependent apoptosis; likely involved in superoxide-mediated regulation of the actin cytoskeleton; member of a conserved superfamily of NADPH oxidases (NOX enzymes); has similarity to iron/copper reductases (FRE1-8), particularly Fre8p; Belongs to the ferric reductase (FRE) family. AIM14 subfamily
Top 10 interactors (score): AFT1 (0.782); MRPL25 (0.691); RAS2 (0.669); NDI1 (0.616); AIM2 (0.573); INA17 (0.562); QRI7 (0.551); MCA1 (0.547); YCK1 (0.523); FMO1 (0.508); ACT1 (0.501); PGA3 (0.495); ERO1 (0.485); BEM1 (0.485); AIM21 (0.483); DUS1 (0.483); YCK2 (0.482); AIF1 (0.482); CBR1 (0.46); NDE2 (0.457)
Homologues (species, bitscore): FRO2 (Arabidopsis thaliana, 57.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:203150-204862:+ | gene-YGL160W_AKU4011 | rna-NM_001181025.1_AKU4011 | cds-NP_011355.1_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000132.1:205542-207254:- | gene-YGL160W_BG1 | rna-NM_001181025.1_BG1 | cds-NP_011355.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:205295-207007:+ | gene-YGL160W_Bruggeman | rna-NM_001181025.1_Bruggeman | cds-NP_011355.1_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:201144-202856:+ | gene-YGL160W_CAT1 | rna-NM_001181025.1_CAT1 | cds-NP_011355.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:206286-207998:+ | gene-YGL160W_CBS1585 | rna-NM_001181025.1_CBS1585 | cds-NP_011355.1_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:201128-202840:+ | gene-YGL160W_CBS436 | rna-NM_001181025.1_CBS436 | cds-NP_011355.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:192742-194454:+ | gene-YGL160W_CBS6412 | rna-NM_001181025.1_CBS6412 | cds-NP_011355.1_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:200591-202303:+ | gene-YGL160W_CBS6413 | rna-NM_001181025.1_CBS6413 | cds-NP_011355.1_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:200823-202535:+ | gene-YGL160W_CENPK1137D | rna-NM_001181025.1_CENPK1137D | cds-NP_011355.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:192947-194659:+ | gene-YGL160W_EthanolRed | rna-NM_001181025.1_EthanolRed | cds-NP_011355.1_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:194193-195905:+ | gene-YGL160W_FaliES1 | rna-NM_001181025.1_FaliES1 | cds-NP_011355.1_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000090.1:44349-46061:+ | gene-YGL160W_JAY291 | rna-NM_001181025.1_JAY291 | cds-NP_011355.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:202519-204231:+ | gene-YGL160W_MUCL30387 | rna-NM_001181025.1_MUCL30387 | cds-NP_011355.1_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:205634-207346:+ | gene-YGL160W_MUCL30388 | rna-NM_001181025.1_MUCL30388 | cds-NP_011355.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:203313-205025:+ | gene-YGL160W_MUCL39482 | rna-NM_001181025.1_MUCL39482 | cds-NP_011355.1_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:205858-207570:+ | gene-YGL160W_MUCL42920 | rna-NM_001181025.1_MUCL42920 | cds-NP_011355.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:200561-202273:+ | gene-YGL160W_NCIM3186 | rna-NM_001181025.1_NCIM3186 | cds-NP_011355.1_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:194778-196490:+ | gene-YGL160W_NCYC1407 | rna-NM_001181025.1_NCYC1407 | cds-NP_011355.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:196651-198363:+ | gene-YGL160W_PE2H3 | rna-NM_001181025.1_PE2H3 | cds-NP_011355.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:196211-197923:+ | gene-YGL160W_PE2H4 | rna-NM_001181025.1_PE2H4 | cds-NP_011355.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:200561-202273:+ | gene-YGL160W_S288C | rna-NM_001181025.1_S288C | cds-NP_011355.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000067.1:60320-62032:+ | gene-YGL160W_SA1 | rna-NM_001181025.1_SA1 | cds-NP_011355.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:194422-196134:+ | gene-YGL160W_ThermosaccDry | rna-NM_001181025.1_ThermosaccDry | cds-NP_011355.1_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:201565-203277:+ | gene-YGL160W_VR1 | rna-NM_001181025.1_VR1 | cds-NP_011355.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:192877-194589:+ | gene-YGL160W_ZTW1 | rna-NM_001181025.1_ZTW1 | cds-NP_011355.1_ZTW1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:199661-201373:+ | gene-YGL160W_Sparadoxus | rna-NM_001181025.1_Sparadoxus | cds-NP_011355.1_Sparadoxus | 88.4 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |