Gene name: AIF1
Reference locus (S288C): YNR074C
Gene biotype: protein_coding
Description: Apoptosis-inducing factor 1; Mitochondrial cell death effector; translocates to the nucleus in response to apoptotic stimuli, homolog of mammalian Apoptosis-Inducing Factor, putative reductase; Belongs to the FAD-dependent oxidoreductase family
Top 10 interactors (score): NUC1 (0.972); YGR054W (0.96); MCA1 (0.944); TDA3 (0.912); BIR1 (0.903); NMA111 (0.898); BXI1 (0.878); CIR2 (0.834); YMR130W (0.824); NDI1 (0.796); CPR3 (0.754); GLR1 (0.697); FYV10 (0.697); FMO1 (0.683); POX1 (0.68); CTT1 (0.675); CDC48 (0.665); TRR1 (0.665); CTA1 (0.653); YAH1 (0.613)
Homologues (species, bitscore): AIFM2 (Homo sapiens, 58.2); Aifm2 (Mus musculus, 57.8); AIFM2 (Danio rerio, 78.6); aifm2 (Xenopus tropicalis, 68.9); AT3G44190 (Arabidopsis thaliana, 75.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000075.1:67805-68941:- | gene-YNR074C_BG1 | rna-NM_001183251.1_BG1 | cds-NP_014472.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | MBVY01000040.1:3843-4979:- | gene-YNR074C_Bruggeman | rna-NM_001183251.1_Bruggeman | cds-NP_014472.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:816009-817145:- | gene-YNR074C_CAT1 | rna-NM_001183251.1_CAT1 | cds-NP_014472.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:829382-830518:- | gene-YNR074C_CBS436 | rna-NM_001183251.1_CBS436 | cds-NP_014472.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000031.1:2641-3777:+ | gene-YNR074C_JAY291 | rna-NM_001183251.1_JAY291 | cds-NP_014472.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | MBVW01000163.1:1278-2414:- | gene-YNR074C_MUCL30388 | rna-NM_001183251.1_MUCL30388 | cds-NP_014472.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:762043-763179:- | gene-YNR074C_PE2H3 | rna-NM_001183251.1_PE2H3 | cds-NP_014472.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:763431-764567:- | gene-YNR074C_PE2H4 | rna-NM_001183251.1_PE2H4 | cds-NP_014472.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:777602-778738:- | gene-YNR074C_S288C | rna-NM_001183251.1_S288C | cds-NP_014472.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000153.1:651-1787:+ | gene-YNR074C_SA1 | rna-NM_001183251.1_SA1 | cds-NP_014472.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:796930-798066:- | gene-YNR074C_VR1 | rna-NM_001183251.1_VR1 | cds-NP_014472.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047491.1:15256-16392:+ | gene-YNR074C_Sparadoxus | rna-NM_001183251.1_Sparadoxus | cds-NP_014472.1_Sparadoxus | 86.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |