AHA1 (YDR214W)


Gene profile

Gene name: AHA1
Reference locus (S288C): YDR214W
Gene biotype: protein_coding

Description: Hsp90 co-chaperone AHA1; Co-chaperone that binds Hsp82p and activates its ATPase activity; plays a role in determining prion variants; similar to Hch1p; expression is regulated by stresses such as heat shock; protein abundance increases in response to DNA replication stress; Belongs to the AHA1 family

Top 10 interactors (score): HCH1 (0.999); SBA1 (0.999); CPR6 (0.999); STI1 (0.999); HSP82 (0.999); HSC82 (0.999); HSP78 (0.991); SIS1 (0.991); HSP104 (0.99); SSE1 (0.989); CDC37 (0.984); SSE2 (0.98); FES1 (0.979); MBF1 (0.973); HSP60 (0.949); SGT1 (0.948); HSP26 (0.933); CPR7 (0.933); YDJ1 (0.923); CCT3 (0.922)

Homologues (species, bitscore): AHSA1 (Homo sapiens, 115.9); Ahsa1 (Mus musculus, 114.0); ahsa1 (Danio rerio, 126.7); ahsa1 (Xenopus tropicalis, 137.5); CG1416 (Drosophila melanogaster, 119.0); ahsa-1 (Caenorhabditis elegans, 88.6); AT3G12050 (Arabidopsis thaliana, 100.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:849576-850628:+ gene-YDR214W_AKU4011 rna-NM_001180522.3_AKU4011 cds-NP_010500.3_AKU4011 99.3 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000080.1:275205-276257:- gene-YDR214W_BG1 rna-NM_001180522.3_BG1 cds-NP_010500.3_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:881908-882960:+ gene-YDR214W_Bruggeman rna-NM_001180522.3_Bruggeman cds-NP_010500.3_Bruggeman 99.4 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:869170-870222:+ gene-YDR214W_CAT1 rna-NM_001180522.3_CAT1 cds-NP_010500.3_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:839928-840980:+ gene-YDR214W_CBS1585 rna-NM_001180522.3_CBS1585 cds-NP_010500.3_CBS1585 99.3 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:868936-869988:+ gene-YDR214W_CBS436 rna-NM_001180522.3_CBS436 cds-NP_010500.3_CBS436 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:836687-837739:+ gene-YDR214W_CBS6412 rna-NM_001180522.3_CBS6412 cds-NP_010500.3_CBS6412 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:867286-868338:+ gene-YDR214W_CBS6413 rna-NM_001180522.3_CBS6413 cds-NP_010500.3_CBS6413 99.3 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:891679-892731:+ gene-YDR214W_CENPK1137D rna-NM_001180522.3_CENPK1137D cds-NP_010500.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:850270-851322:+ gene-YDR214W_EthanolRed rna-NM_001180522.3_EthanolRed cds-NP_010500.3_EthanolRed 99.3 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:858471-859523:+ gene-YDR214W_FaliES1 rna-NM_001180522.3_FaliES1 cds-NP_010500.3_FaliES1 99.3 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000348.1:52050-53102:- gene-YDR214W_JAY291 rna-NM_001180522.3_JAY291 cds-NP_010500.3_JAY291 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:867559-868611:+ gene-YDR214W_MUCL30387 rna-NM_001180522.3_MUCL30387 cds-NP_010500.3_MUCL30387 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:855813-856865:+ gene-YDR214W_MUCL30388 rna-NM_001180522.3_MUCL30388 cds-NP_010500.3_MUCL30388 99.4 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:841337-842389:+ gene-YDR214W_MUCL39482 rna-NM_001180522.3_MUCL39482 cds-NP_010500.3_MUCL39482 99.3 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:780620-781672:+ gene-YDR214W_MUCL42920 rna-NM_001180522.3_MUCL42920 cds-NP_010500.3_MUCL42920 99.9 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:892798-893850:+ gene-YDR214W_NCIM3186 rna-NM_001180522.3_NCIM3186 cds-NP_010500.3_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:845002-846054:+ gene-YDR214W_NCYC1407 rna-NM_001180522.3_NCYC1407 cds-NP_010500.3_NCYC1407 99.3 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:861227-862279:+ gene-YDR214W_PE2H3 rna-NM_001180522.3_PE2H3 cds-NP_010500.3_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:866508-867560:+ gene-YDR214W_PE2H4 rna-NM_001180522.3_PE2H4 cds-NP_010500.3_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:892875-893927:+ gene-YDR214W_S288C rna-NM_001180522.3_S288C cds-NP_010500.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000013.1:98982-100034:+ gene-YDR214W_SA1 rna-NM_001180522.3_SA1 cds-NP_010500.3_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:856627-857679:+ gene-YDR214W_ThermosaccDry rna-NM_001180522.3_ThermosaccDry cds-NP_010500.3_ThermosaccDry 99.3 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:871832-872884:+ gene-YDR214W_VR1 rna-NM_001180522.3_VR1 cds-NP_010500.3_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000007.1:119344-120396:+ gene-YDR214W_ZTW1 rna-NM_001180522.3_ZTW1 cds-NP_010500.3_ZTW1 99.3 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:861762-862808:+ gene-YDR214W_Sparadoxus rna-NM_001180522.3_Sparadoxus cds-NP_010500.3_Sparadoxus 88.7 99.3 Verified 1 1 1 False True False False False

Additional files