AGX1 (YFL030W)


Gene profile

Gene name: AGX1
Reference locus (S288C): YFL030W
Gene biotype: protein_coding

Description: Alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase; Alanine--glyoxylate aminotransferase 1; Alanine:glyoxylate aminotransferase (AGT); catalyzes the synthesis of glycine from glyoxylate, which is one of three pathways for glycine biosynthesis in yeast; similar to mammalian and plant alanine:glyoxylate aminotransferases; human homolog AGXT complements yeast null mutant; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family

Top 10 interactors (score): GLY1 (0.998); SHM2 (0.996); GOR1 (0.993); CYB2 (0.988); GCV1 (0.984); ICL1 (0.982); MLS1 (0.982); SER2 (0.977); ALT1 (0.977); GCV3 (0.975); ACO1 (0.973); GCV2 (0.973); FUM1 (0.973); YFR006W (0.971); ALT2 (0.967); TPI1 (0.966); DAL7 (0.964); SHM1 (0.959); AAT1 (0.958); LPD1 (0.953)

Homologues (species, bitscore): AGXT (Homo sapiens, 91.7); Agxt (Mus musculus, 84.7); agxta (Danio rerio, 95.5); agxt (Xenopus tropicalis, 89.4); Spat (Drosophila melanogaster, 100.9); T14D7.1 (Caenorhabditis elegans, 114.4); AGT (Arabidopsis thaliana, 124.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005300.1:73185-74342:+ gene-YFL030W_AKU4011 rna-NM_001179936.1_AKU4011 cds-NP_116623.1_AKU4011 99.5 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000089.1:3513-4670:+ gene-YFL030W_BG1 rna-NM_001179936.1_BG1 cds-NP_116623.1_BG1 99.3 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005508.1:72053-73210:+ gene-YFL030W_Bruggeman rna-NM_001179936.1_Bruggeman cds-NP_116623.1_Bruggeman 99.2 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005524.1:77202-78359:+ gene-YFL030W_CAT1 rna-NM_001179936.1_CAT1 cds-NP_116623.1_CAT1 99.3 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005364.1:73993-75150:+ gene-YFL030W_CBS1585 rna-NM_001179936.1_CBS1585 cds-NP_116623.1_CBS1585 99.5 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005348.1:47501-48658:+ gene-YFL030W_CBS436 rna-NM_001179936.1_CBS436 cds-NP_116623.1_CBS436 99.2 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005332.1:73727-74884:+ gene-YFL030W_CBS6412 rna-NM_001179936.1_CBS6412 cds-NP_116623.1_CBS6412 99.5 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005316.1:76262-77419:+ gene-YFL030W_CBS6413 rna-NM_001179936.1_CBS6413 cds-NP_116623.1_CBS6413 99.5 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001527.1:73157-74314:+ gene-YFL030W_CENPK1137D rna-NM_001179936.1_CENPK1137D cds-NP_116623.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005476.1:72146-73303:+ gene-YFL030W_EthanolRed rna-NM_001179936.1_EthanolRed cds-NP_116623.1_EthanolRed 99.3 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005540.1:73785-74942:+ gene-YFL030W_FaliES1 rna-NM_001179936.1_FaliES1 cds-NP_116623.1_FaliES1 99.4 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000448.1:82182-83339:+ gene-YFL030W_JAY291 rna-NM_001179936.1_JAY291 cds-NP_116623.1_JAY291 99.2 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005412.1:74156-75313:+ gene-YFL030W_MUCL30387 rna-NM_001179936.1_MUCL30387 cds-NP_116623.1_MUCL30387 99.2 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005444.1:72087-73244:+ gene-YFL030W_MUCL30388 rna-NM_001179936.1_MUCL30388 cds-NP_116623.1_MUCL30388 99.1 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005284.1:72378-73535:+ gene-YFL030W_MUCL39482 rna-NM_001179936.1_MUCL39482 cds-NP_116623.1_MUCL39482 99.5 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005428.1:70490-71647:+ gene-YFL030W_MUCL42920 rna-NM_001179936.1_MUCL42920 cds-NP_116623.1_MUCL42920 99.2 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011815.1:76830-77987:+ gene-YFL030W_NCIM3186 rna-NM_001179936.1_NCIM3186 cds-NP_116623.1_NCIM3186 98.9 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005268.1:73467-74624:+ gene-YFL030W_NCYC1407 rna-NM_001179936.1_NCYC1407 cds-NP_116623.1_NCYC1407 99.4 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994145.1:93362-94519:+ gene-YFL030W_PE2H3 rna-NM_001179936.1_PE2H3 cds-NP_116623.1_PE2H3 99.5 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999877.1:92913-94070:+ gene-YFL030W_PE2H4 rna-NM_001179936.1_PE2H4 cds-NP_116623.1_PE2H4 99.5 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001138.5:76831-77988:+ gene-YFL030W_S288C rna-NM_001179936.1_S288C cds-NP_116623.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000117.1:901-2058:+ gene-YFL030W_SA1 rna-NM_001179936.1_SA1 cds-NP_116623.1_SA1 99.2 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005492.1:72968-74125:+ gene-YFL030W_ThermosaccDry rna-NM_001179936.1_ThermosaccDry cds-NP_116623.1_ThermosaccDry 99.3 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005460.1:81510-82667:+ gene-YFL030W_VR1 rna-NM_001179936.1_VR1 cds-NP_116623.1_VR1 99.2 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000013.1:3446-4603:+ gene-YFL030W_ZTW1 rna-NM_001179936.1_ZTW1 cds-NP_116623.1_ZTW1 99.3 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047492.1:97224-98381:+ gene-YFL030W_Sparadoxus rna-NM_001179936.1_Sparadoxus cds-NP_116623.1_Sparadoxus 90.9 100.0 Verified 1 1 1 False True False False False

Additional files