AGP1 (YCL025C)


Gene profile

Gene name: AGP1
Reference locus (S288C): YCL025C
Gene biotype: protein_coding

Description: Low-affinity amino acid permease with broad substrate range; involved in uptake of asparagine, glutamine, and other amino acids; expression regulated by SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p); AGP1 has a paralog, GNP1, that arose from the whole genome duplication; Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family

Top 10 interactors (score): GNP1 (0.999); TAT1 (0.923); GAP1 (0.793); PTR2 (0.78); PTR3 (0.78); SSY5 (0.779); MEP2 (0.754); STP1 (0.747); STP2 (0.705); RNH201 (0.693); MEP1 (0.679); AVT5 (0.643); SHR3 (0.641); MEP3 (0.631); DAL81 (0.582); ASI1 (0.573); MUP1 (0.565); GLT1 (0.526); POL2 (0.52); DAL5 (0.52)

Homologues (species, bitscore): SLC7A14 (Homo sapiens, 63.2); Slc7a8 (Mus musculus, 64.7); slc7a8a (Danio rerio, 62.0); slc7a5 (Xenopus tropicalis, 67.0); aat-1 (Caenorhabditis elegans, 59.3); At5g36940 (Arabidopsis thaliana, 64.7)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005297.1:77379-79280:- gene-YCL025C_AKU4011 rna-NM_001178671.1_AKU4011 cds-NP_009905.3_AKU4011 99.2 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000178.1:67830-69731:+ gene-YCL025C_BG1 rna-NM_001178671.1_BG1 cds-NP_009905.3_BG1 99.3 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005505.1:65569-67470:- gene-YCL025C_Bruggeman rna-NM_001178671.1_Bruggeman cds-NP_009905.3_Bruggeman 99.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005521.1:77183-79084:- gene-YCL025C_CAT1 rna-NM_001178671.1_CAT1 cds-NP_009905.3_CAT1 99.5 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005361.1:78027-79928:- gene-YCL025C_CBS1585 rna-NM_001178671.1_CBS1585 cds-NP_009905.3_CBS1585 99.3 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005345.1:76510-78411:- gene-YCL025C_CBS436 rna-NM_001178671.1_CBS436 cds-NP_009905.3_CBS436 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005329.1:65477-67378:- gene-YCL025C_CBS6412 rna-NM_001178671.1_CBS6412 cds-NP_009905.3_CBS6412 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005313.1:76844-78745:- gene-YCL025C_CBS6413 rna-NM_001178671.1_CBS6413 cds-NP_009905.3_CBS6413 99.3 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001524.1:75615-77516:- gene-YCL025C_CENPK1137D rna-NM_001178671.1_CENPK1137D cds-NP_009905.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005473.1:75397-77298:- gene-YCL025C_EthanolRed rna-NM_001178671.1_EthanolRed cds-NP_009905.3_EthanolRed 99.3 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005537.1:76357-78258:- gene-YCL025C_FaliES1 rna-NM_001178671.1_FaliES1 cds-NP_009905.3_FaliES1 99.3 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000225.1:6165-8066:+ gene-YCL025C_JAY291 rna-NM_001178671.1_JAY291 cds-NP_009905.3_JAY291 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005409.1:63750-65651:- gene-YCL025C_MUCL30387 rna-NM_001178671.1_MUCL30387 cds-NP_009905.3_MUCL30387 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005441.1:64034-65935:- gene-YCL025C_MUCL30388 rna-NM_001178671.1_MUCL30388 cds-NP_009905.3_MUCL30388 99.8 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005281.1:78443-80344:- gene-YCL025C_MUCL39482 rna-NM_001178671.1_MUCL39482 cds-NP_009905.3_MUCL39482 99.3 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005425.1:64556-66457:- gene-YCL025C_MUCL42920 rna-NM_001178671.1_MUCL42920 cds-NP_009905.3_MUCL42920 99.7 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011812.1:75650-77551:- gene-YCL025C_NCIM3186 rna-NM_001178671.1_NCIM3186 cds-NP_009905.3_NCIM3186 99.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005265.1:78927-80828:- gene-YCL025C_NCYC1407 rna-NM_001178671.1_NCYC1407 cds-NP_009905.3_NCYC1407 99.3 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994142.1:76445-78346:- gene-YCL025C_PE2H3 rna-NM_001178671.1_PE2H3 cds-NP_009905.3_PE2H3 99.5 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999874.1:76402-78303:- gene-YCL025C_PE2H4 rna-NM_001178671.1_PE2H4 cds-NP_009905.3_PE2H4 99.5 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001135.5:76018-77919:- gene-YCL025C_S288C rna-NM_001178671.1_S288C cds-NP_009905.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000061.1:63148-65049:- gene-YCL025C_SA1 rna-NM_001178671.1_SA1 cds-NP_009905.3_SA1 99.3 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005489.1:76658-78559:- gene-YCL025C_ThermosaccDry rna-NM_001178671.1_ThermosaccDry cds-NP_009905.3_ThermosaccDry 99.3 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005457.1:82933-84834:- gene-YCL025C_VR1 rna-NM_001178671.1_VR1 cds-NP_009905.3_VR1 99.5 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000004.1:76853-78754:- gene-YCL025C_ZTW1 rna-NM_001178671.1_ZTW1 cds-NP_009905.3_ZTW1 99.5 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047489.1:106374-108275:- gene-YCL025C_Sparadoxus rna-NM_001178671.1_Sparadoxus cds-NP_009905.3_Sparadoxus 92.6 100.0 Verified 1 1 1 False True False False False

Additional files