AGE1 (YDR524C)


Gene profile

Gene name: AGE1
Reference locus (S288C): YDR524C
Gene biotype: protein_coding

Description: ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector; involved in the secretory and endocytic pathways; contains C2C2H2 cysteine/histidine motif

Top 10 interactors (score): ARF1 (0.934); ARF3 (0.875); ARF2 (0.844); SYT1 (0.828); SPS18 (0.813); SAC1 (0.759); ARL1 (0.75); GEA2 (0.729); GEA1 (0.711); EXO70 (0.706); RBH1 (0.694); YPT31 (0.686); YPT32 (0.686); STE3 (0.677); COP1 (0.67); SCS7 (0.663); YPT11 (0.655); SNU13 (0.651); RVS161 (0.65); LRG1 (0.646)

Homologues (species, bitscore): ACAP1 (Homo sapiens, 98.2); Acap3 (Mus musculus, 97.4); asap1 (Danio rerio, 98.6); acap3 (Xenopus tropicalis, 94.4); CenG1A (Drosophila melanogaster, 95.1); cnt-2 (Caenorhabditis elegans, 93.6); ZAC (Arabidopsis thaliana, 80.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:1427582-1429030:- gene-YDR524C_AKU4011 rna-NM_001180832.3_AKU4011 cds-NP_010812.3_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000073.1:69209-70657:- gene-YDR524C_BG1 rna-NM_001180832.3_BG1 cds-NP_010812.3_BG1 99.3 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:1458876-1460324:- gene-YDR524C_Bruggeman rna-NM_001180832.3_Bruggeman cds-NP_010812.3_Bruggeman 99.1 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:1436038-1437486:- gene-YDR524C_CAT1 rna-NM_001180832.3_CAT1 cds-NP_010812.3_CAT1 99.5 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:1422310-1423758:- gene-YDR524C_CBS1585 rna-NM_001180832.3_CBS1585 cds-NP_010812.3_CBS1585 99.9 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:1441517-1442965:- gene-YDR524C_CBS436 rna-NM_001180832.3_CBS436 cds-NP_010812.3_CBS436 99.2 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:1417473-1418921:- gene-YDR524C_CBS6412 rna-NM_001180832.3_CBS6412 cds-NP_010812.3_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:1440970-1442418:- gene-YDR524C_CBS6413 rna-NM_001180832.3_CBS6413 cds-NP_010812.3_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:1486228-1487676:- gene-YDR524C_CENPK1137D rna-NM_001180832.3_CENPK1137D cds-NP_010812.3_CENPK1137D 99.5 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:1430842-1432290:- gene-YDR524C_EthanolRed rna-NM_001180832.3_EthanolRed cds-NP_010812.3_EthanolRed 99.9 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:1434394-1435842:- gene-YDR524C_FaliES1 rna-NM_001180832.3_FaliES1 cds-NP_010812.3_FaliES1 99.9 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000026.1:132740-134188:- gene-YDR524C_JAY291 rna-NM_001180832.3_JAY291 cds-NP_010812.3_JAY291 99.3 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:1441970-1443418:- gene-YDR524C_MUCL30387 rna-NM_001180832.3_MUCL30387 cds-NP_010812.3_MUCL30387 99.2 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:1423415-1424863:- gene-YDR524C_MUCL30388 rna-NM_001180832.3_MUCL30388 cds-NP_010812.3_MUCL30388 99.1 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:1413808-1415256:- gene-YDR524C_MUCL39482 rna-NM_001180832.3_MUCL39482 cds-NP_010812.3_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:1356445-1357893:- gene-YDR524C_MUCL42920 rna-NM_001180832.3_MUCL42920 cds-NP_010812.3_MUCL42920 99.2 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:1487465-1488913:- gene-YDR524C_NCIM3186 rna-NM_001180832.3_NCIM3186 cds-NP_010812.3_NCIM3186 99.1 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:1427100-1428548:- gene-YDR524C_NCYC1407 rna-NM_001180832.3_NCYC1407 cds-NP_010812.3_NCYC1407 99.9 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:1438008-1439456:- gene-YDR524C_PE2H3 rna-NM_001180832.3_PE2H3 cds-NP_010812.3_PE2H3 99.3 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:1443476-1444924:- gene-YDR524C_PE2H4 rna-NM_001180832.3_PE2H4 cds-NP_010812.3_PE2H4 99.3 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:1487542-1488990:- gene-YDR524C_S288C rna-NM_001180832.3_S288C cds-NP_010812.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000004.1:128121-129569:+ gene-YDR524C_SA1 rna-NM_001180832.3_SA1 cds-NP_010812.3_SA1 99.3 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:1438616-1440064:- gene-YDR524C_ThermosaccDry rna-NM_001180832.3_ThermosaccDry cds-NP_010812.3_ThermosaccDry 99.9 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:1454390-1455838:- gene-YDR524C_VR1 rna-NM_001180832.3_VR1 cds-NP_010812.3_VR1 99.3 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000008.1:481258-482706:- gene-YDR524C_ZTW1 rna-NM_001180832.3_ZTW1 cds-NP_010812.3_ZTW1 99.7 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:1447555-1449003:- gene-YDR524C_Sparadoxus rna-NM_001180832.3_Sparadoxus cds-NP_010812.3_Sparadoxus 90.2 100.0 Verified 1 1 1 False True False False False

Additional files