AGC1 (YPR021C)


Gene profile

Gene name: AGC1
Reference locus (S288C): YPR021C
Gene biotype: protein_coding

Description: Solute carrier family 25 (mitochondrial aspartate/glutamate transporter), member 12/13; Mitochondrial amino acid transporter; acts both as a glutamate uniporter and as an aspartate-glutamate exchanger; involved in nitrogen metabolism and nitrogen compound biosynthesis; human homolog SLC25A13 complements yeast null mutant

Top 10 interactors (score): CYT1 (0.972); COX6 (0.964); ACO1 (0.892); ATP4 (0.703); ACO2 (0.697); AAT1 (0.689); YGR039W (0.678); DAL2 (0.676); ALT2 (0.675); PEX2 (0.669); AGX1 (0.668); ALT1 (0.663); PEX7 (0.659); SPT3 (0.651); FRS1 (0.651); PEX3 (0.645); PTC1 (0.643); LYS4 (0.643); TIM13 (0.619); ITR1 (0.613)

Homologues (species, bitscore): SLC25A13 (Homo sapiens, 316.2); Slc25a12 (Mus musculus, 321.2); slc25a12 (Danio rerio, 323.6); slc25a12 (Xenopus tropicalis, 328.6); aralar1 (Drosophila melanogaster, 330.5); K02F3.2 (Caenorhabditis elegans, 298.9); NDT2 (Arabidopsis thaliana, 155.6)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005310.1:572302-575010:- gene-YPR021C_AKU4011 rna-NM_001184118.1_AKU4011 cds-NP_015346.1_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000091.1:322123-324831:+ gene-YPR021C_BG1 rna-NM_001184118.1_BG1 cds-NP_015346.1_BG1 99.3 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005518.1:649964-652672:- gene-YPR021C_Bruggeman rna-NM_001184118.1_Bruggeman cds-NP_015346.1_Bruggeman 99.7 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005534.1:693463-696171:- gene-YPR021C_CAT1 rna-NM_001184118.1_CAT1 cds-NP_015346.1_CAT1 99.5 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005374.1:575988-578696:- gene-YPR021C_CBS1585 rna-NM_001184118.1_CBS1585 cds-NP_015346.1_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005358.1:590360-593068:- gene-YPR021C_CBS436 rna-NM_001184118.1_CBS436 cds-NP_015346.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005342.1:579737-582445:- gene-YPR021C_CBS6412 rna-NM_001184118.1_CBS6412 cds-NP_015346.1_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005326.1:572452-575160:- gene-YPR021C_CBS6413 rna-NM_001184118.1_CBS6413 cds-NP_015346.1_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001537.1:600622-603330:- gene-YPR021C_CENPK1137D rna-NM_001184118.1_CENPK1137D cds-NP_015346.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:570235-572943:- gene-YPR021C_EthanolRed rna-NM_001184118.1_EthanolRed cds-NP_015346.1_EthanolRed 99.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005550.1:578037-580745:- gene-YPR021C_FaliES1 rna-NM_001184118.1_FaliES1 cds-NP_015346.1_FaliES1 99.5 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000116.1:46690-49398:+ gene-YPR021C_JAY291 rna-NM_001184118.1_JAY291 cds-NP_015346.1_JAY291 99.2 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005422.1:591184-593892:- gene-YPR021C_MUCL30387 rna-NM_001184118.1_MUCL30387 cds-NP_015346.1_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005454.1:589837-592545:- gene-YPR021C_MUCL30388 rna-NM_001184118.1_MUCL30388 cds-NP_015346.1_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005294.1:569229-571937:- gene-YPR021C_MUCL39482 rna-NM_001184118.1_MUCL39482 cds-NP_015346.1_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005438.1:630562-633270:- gene-YPR021C_MUCL42920 rna-NM_001184118.1_MUCL42920 cds-NP_015346.1_MUCL42920 99.7 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011825.1:600632-603340:- gene-YPR021C_NCIM3186 rna-NM_001184118.1_NCIM3186 cds-NP_015346.1_NCIM3186 95.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005278.1:577176-579884:- gene-YPR021C_NCYC1407 rna-NM_001184118.1_NCYC1407 cds-NP_015346.1_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994155.1:583907-586615:- gene-YPR021C_PE2H3 rna-NM_001184118.1_PE2H3 cds-NP_015346.1_PE2H3 99.3 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999887.1:583525-586233:- gene-YPR021C_PE2H4 rna-NM_001184118.1_PE2H4 cds-NP_015346.1_PE2H4 99.2 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001148.4:600649-603357:- gene-YPR021C_S288C rna-NM_001184118.1_S288C cds-NP_015346.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000026.1:96953-99661:+ gene-YPR021C_SA1 rna-NM_001184118.1_SA1 cds-NP_015346.1_SA1 99.7 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005502.1:577839-580547:- gene-YPR021C_ThermosaccDry rna-NM_001184118.1_ThermosaccDry cds-NP_015346.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005470.1:594079-596787:- gene-YPR021C_VR1 rna-NM_001184118.1_VR1 cds-NP_015346.1_VR1 99.7 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000033.1:577144-579852:- gene-YPR021C_ZTW1 rna-NM_001184118.1_ZTW1 cds-NP_015346.1_ZTW1 99.7 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047502.1:577311-580019:- gene-YPR021C_Sparadoxus rna-NM_001184118.1_Sparadoxus cds-NP_015346.1_Sparadoxus 90.5 100.0 Verified 1 1 1 False True False False False

Additional files