Gene name: AFT2
Reference locus (S288C): YPL202C
Gene biotype: protein_coding
Description: Iron-regulated transcriptional activator; activates genes involved in intracellular iron use and required for iron homeostasis and resistance to oxidative stress; AFT2 has a paralog, AFT1, that arose from the whole genome duplication
Top 10 interactors (score): GRX3 (0.956); BOL2 (0.942); FET3 (0.891); TIS11 (0.867); AFT1 (0.842); SMF3 (0.82); MSN5 (0.818); YAP5 (0.815); FRE1 (0.812); NHP6A (0.78); YFH1 (0.78); FTR1 (0.78); NHP6B (0.78); CCC1 (0.779); FRA1 (0.768); MRS4 (0.766); ATM1 (0.75); ARN1 (0.748); GRX4 (0.745); FET4 (0.716)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:145955-147205:- | gene-YPL202C_AKU4011 | rna-NM_001184016.1_AKU4011 | cds-NP_015122.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000069.1:351727-352977:- | gene-YPL202C_BG1 | rna-NM_001184016.1_BG1 | cds-NP_015122.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:171425-172675:- | gene-YPL202C_Bruggeman | rna-NM_001184016.1_Bruggeman | cds-NP_015122.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:168029-169279:- | gene-YPL202C_CAT1 | rna-NM_001184016.1_CAT1 | cds-NP_015122.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:150141-151391:- | gene-YPL202C_CBS1585 | rna-NM_001184016.1_CBS1585 | cds-NP_015122.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:164569-165819:- | gene-YPL202C_CBS436 | rna-NM_001184016.1_CBS436 | cds-NP_015122.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:154944-156194:- | gene-YPL202C_CBS6412 | rna-NM_001184016.1_CBS6412 | cds-NP_015122.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:146318-147568:- | gene-YPL202C_CBS6413 | rna-NM_001184016.1_CBS6413 | cds-NP_015122.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:168035-169285:- | gene-YPL202C_CENPK1137D | rna-NM_001184016.1_CENPK1137D | cds-NP_015122.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:145073-146323:- | gene-YPL202C_EthanolRed | rna-NM_001184016.1_EthanolRed | cds-NP_015122.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:152279-153529:- | gene-YPL202C_FaliES1 | rna-NM_001184016.1_FaliES1 | cds-NP_015122.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000069.1:4791-6041:+ | gene-YPL202C_JAY291 | rna-NM_001184016.1_JAY291 | cds-NP_015122.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:163137-164387:- | gene-YPL202C_MUCL30387 | rna-NM_001184016.1_MUCL30387 | cds-NP_015122.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:161321-162571:- | gene-YPL202C_MUCL30388 | rna-NM_001184016.1_MUCL30388 | cds-NP_015122.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:143271-144521:- | gene-YPL202C_MUCL39482 | rna-NM_001184016.1_MUCL39482 | cds-NP_015122.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:162159-163409:- | gene-YPL202C_MUCL42920 | rna-NM_001184016.1_MUCL42920 | cds-NP_015122.1_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:168071-169321:- | gene-YPL202C_NCIM3186 | rna-NM_001184016.1_NCIM3186 | cds-NP_015122.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:149720-150970:- | gene-YPL202C_NCYC1407 | rna-NM_001184016.1_NCYC1407 | cds-NP_015122.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:157439-158689:- | gene-YPL202C_PE2H3 | rna-NM_001184016.1_PE2H3 | cds-NP_015122.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:157082-158332:- | gene-YPL202C_PE2H4 | rna-NM_001184016.1_PE2H4 | cds-NP_015122.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:168088-169338:- | gene-YPL202C_S288C | rna-NM_001184016.1_S288C | cds-NP_015122.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000095.1:4847-6097:+ | gene-YPL202C_SA1 | rna-NM_001184016.1_SA1 | cds-NP_015122.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:152060-153310:- | gene-YPL202C_ThermosaccDry | rna-NM_001184016.1_ThermosaccDry | cds-NP_015122.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:166969-168219:- | gene-YPL202C_VR1 | rna-NM_001184016.1_VR1 | cds-NP_015122.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:151580-152830:- | gene-YPL202C_ZTW1 | rna-NM_001184016.1_ZTW1 | cds-NP_015122.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:153137-154378:- | gene-YPL202C_Sparadoxus | rna-NM_001184016.1_Sparadoxus | cds-NP_015122.1_Sparadoxus | 86.5 | 98.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |