AFR1 (YDR085C)


Gene profile

Gene name: AFR1
Reference locus (S288C): YDR085C
Gene biotype: protein_coding

Description: Protein required for pheromone-induced projection (shmoo) formation; regulates septin architecture during mating; has an RVXF motif that mediates targeting of Glc7p to mating projections; interacts with Cdc12p; AFR1 has a paralog, YER158C, that arose from the whole genome duplication

Top 10 interactors (score): CDC12 (0.961); YER158C (0.926); BNI4 (0.919); ERG11 (0.78); STE2 (0.773); ASG7 (0.692); SST2 (0.616); SEY1 (0.614); FUS2 (0.599); TPS2 (0.589); GLC7 (0.576); FUS1 (0.569); GIS1 (0.564); MDR1 (0.528); GLO3 (0.525); KAR5 (0.499); AKR1 (0.481); SRL3 (0.478); CDC10 (0.473); FMP16 (0.471)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:591847-593709:- gene-YDR085C_AKU4011 rna-NM_001180393.1_AKU4011 cds-NP_010370.1_AKU4011 98.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000080.1:531609-533471:+ gene-YDR085C_BG1 rna-NM_001180393.1_BG1 cds-NP_010370.1_BG1 99.3 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:624075-625937:- gene-YDR085C_Bruggeman rna-NM_001180393.1_Bruggeman cds-NP_010370.1_Bruggeman 98.4 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:607716-610624:- gene-YDR085C_CAT1 rna-NM_001180393.1_CAT1 cds-NP_010370.1_CAT1 63.4 100.0 Unannotated 1 1 0 False False False True False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:582866-584728:- gene-YDR085C_CBS1585 rna-NM_001180393.1_CBS1585 cds-NP_010370.1_CBS1585 98.4 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:607883-609745:- gene-YDR085C_CBS436 rna-NM_001180393.1_CBS436 cds-NP_010370.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:579281-581143:- gene-YDR085C_CBS6412 rna-NM_001180393.1_CBS6412 cds-NP_010370.1_CBS6412 98.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:607811-609673:- gene-YDR085C_CBS6413 rna-NM_001180393.1_CBS6413 cds-NP_010370.1_CBS6413 98.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:613333-615195:- gene-YDR085C_CENPK1137D rna-NM_001180393.1_CENPK1137D cds-NP_010370.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:593638-595500:- gene-YDR085C_EthanolRed rna-NM_001180393.1_EthanolRed cds-NP_010370.1_EthanolRed 98.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:600432-602294:- gene-YDR085C_FaliES1 rna-NM_001180393.1_FaliES1 cds-NP_010370.1_FaliES1 98.6 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000358.1:28974-30836:+ gene-YDR085C_JAY291 rna-NM_001180393.1_JAY291 cds-NP_010370.1_JAY291 99.1 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:608692-610554:- gene-YDR085C_MUCL30387 rna-NM_001180393.1_MUCL30387 cds-NP_010370.1_MUCL30387 98.4 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:599004-600866:- gene-YDR085C_MUCL30388 rna-NM_001180393.1_MUCL30388 cds-NP_010370.1_MUCL30388 98.4 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:584236-586098:- gene-YDR085C_MUCL39482 rna-NM_001180393.1_MUCL39482 cds-NP_010370.1_MUCL39482 98.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:515688-517550:- gene-YDR085C_MUCL42920 rna-NM_001180393.1_MUCL42920 cds-NP_010370.1_MUCL42920 99.0 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:614211-616073:- gene-YDR085C_NCIM3186 rna-NM_001180393.1_NCIM3186 cds-NP_010370.1_NCIM3186 98.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:583143-585005:- gene-YDR085C_NCYC1407 rna-NM_001180393.1_NCYC1407 cds-NP_010370.1_NCYC1407 98.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:602613-604475:- gene-YDR085C_PE2H3 rna-NM_001180393.1_PE2H3 cds-NP_010370.1_PE2H3 99.7 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:601918-603780:- gene-YDR085C_PE2H4 rna-NM_001180393.1_PE2H4 cds-NP_010370.1_PE2H4 99.7 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:614288-616150:- gene-YDR085C_S288C rna-NM_001180393.1_S288C cds-NP_010370.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000011.1:29184-31046:+ gene-YDR085C_SA1 rna-NM_001180393.1_SA1 cds-NP_010370.1_SA1 99.7 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:599962-601824:- gene-YDR085C_ThermosaccDry rna-NM_001180393.1_ThermosaccDry cds-NP_010370.1_ThermosaccDry 98.5 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:612513-614375:- gene-YDR085C_VR1 rna-NM_001180393.1_VR1 cds-NP_010370.1_VR1 99.4 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000006.1:597545-599407:- gene-YDR085C_ZTW1 rna-NM_001180393.1_ZTW1 cds-NP_010370.1_ZTW1 98.4 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:602248-604110:- gene-YDR085C_Sparadoxus rna-NM_001180393.1_Sparadoxus cds-NP_010370.1_Sparadoxus 85.0 99.7 Verified 1 1 1 False True False False False

Additional files