Gene name: AFG1
Reference locus (S288C): YEL052W
Gene biotype: protein_coding
Description: Peroxisome-assembly atpase; Protein that may act as a chaperone for cytochrome c oxidase subunits; conserved protein; may act as a chaperone in the degradation of misfolded or unassembled cytochrome c oxidase subunits; localized to matrix face of the mitochondrial inner membrane; member of the AAA family but lacks a protease domain
Top 10 interactors (score): AFG2 (0.982); AFG3 (0.687); YTA12 (0.581); SDH2 (0.527); COX11 (0.525); JLP1 (0.483); PUF3 (0.469); DNL4 (0.427); OMA1 (0.422); SDH1 (0.417); SWH1 (0.409); DIC1 (0.405)
Homologues (species, bitscore): LACE1 (Homo sapiens, 251.5); Lace1 (Mus musculus, 257.3); lace1b (Danio rerio, 237.3); LACE1 (Xenopus tropicalis, 245.7); CG8520 (Drosophila melanogaster, 223.8); C30F12.2 (Caenorhabditis elegans, 240.4); AT4G28070 (Arabidopsis thaliana, 198.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005299.1:50976-52505:+ | gene-YEL052W_AKU4011 | rna-NM_001178867.1_AKU4011 | cds-NP_010862.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000075.1:28011-29540:- | gene-YEL052W_BG1 | rna-NM_001178867.1_BG1 | cds-NP_010862.1_BG1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005507.1:54495-56024:+ | gene-YEL052W_Bruggeman | rna-NM_001178867.1_Bruggeman | cds-NP_010862.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005523.1:52918-54447:+ | gene-YEL052W_CAT1 | rna-NM_001178867.1_CAT1 | cds-NP_010862.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005363.1:50923-52452:+ | gene-YEL052W_CBS1585 | rna-NM_001178867.1_CBS1585 | cds-NP_010862.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005347.1:51981-53510:+ | gene-YEL052W_CBS436 | rna-NM_001178867.1_CBS436 | cds-NP_010862.1_CBS436 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005331.1:51173-52702:+ | gene-YEL052W_CBS6412 | rna-NM_001178867.1_CBS6412 | cds-NP_010862.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005315.1:55817-57346:+ | gene-YEL052W_CBS6413 | rna-NM_001178867.1_CBS6413 | cds-NP_010862.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001526.1:54411-55940:+ | gene-YEL052W_CENPK1137D | rna-NM_001178867.1_CENPK1137D | cds-NP_010862.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005475.1:50733-52262:+ | gene-YEL052W_EthanolRed | rna-NM_001178867.1_EthanolRed | cds-NP_010862.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005539.1:50996-52525:+ | gene-YEL052W_FaliES1 | rna-NM_001178867.1_FaliES1 | cds-NP_010862.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000427.1:5530-7059:- | gene-YEL052W_JAY291 | rna-NM_001178867.1_JAY291 | cds-NP_010862.1_JAY291 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005411.1:54927-56456:+ | gene-YEL052W_MUCL30387 | rna-NM_001178867.1_MUCL30387 | cds-NP_010862.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005443.1:51044-52573:+ | gene-YEL052W_MUCL30388 | rna-NM_001178867.1_MUCL30388 | cds-NP_010862.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005283.1:50290-51819:+ | gene-YEL052W_MUCL39482 | rna-NM_001178867.1_MUCL39482 | cds-NP_010862.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005427.1:54929-56458:+ | gene-YEL052W_MUCL42920 | rna-NM_001178867.1_MUCL42920 | cds-NP_010862.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011814.1:56570-58099:+ | gene-YEL052W_NCIM3186 | rna-NM_001178867.1_NCIM3186 | cds-NP_010862.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005267.1:55385-56914:+ | gene-YEL052W_NCYC1407 | rna-NM_001178867.1_NCYC1407 | cds-NP_010862.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994144.1:59397-60926:+ | gene-YEL052W_PE2H3 | rna-NM_001178867.1_PE2H3 | cds-NP_010862.1_PE2H3 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999876.1:55313-56842:+ | gene-YEL052W_PE2H4 | rna-NM_001178867.1_PE2H4 | cds-NP_010862.1_PE2H4 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001137.3:56571-58100:+ | gene-YEL052W_S288C | rna-NM_001178867.1_S288C | cds-NP_010862.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000053.1:28899-30428:- | gene-YEL052W_SA1 | rna-NM_001178867.1_SA1 | cds-NP_010862.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005491.1:51396-52925:+ | gene-YEL052W_ThermosaccDry | rna-NM_001178867.1_ThermosaccDry | cds-NP_010862.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005459.1:50604-52133:+ | gene-YEL052W_VR1 | rna-NM_001178867.1_VR1 | cds-NP_010862.1_VR1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000009.1:50332-51861:+ | gene-YEL052W_ZTW1 | rna-NM_001178867.1_ZTW1 | cds-NP_010862.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047491.1:54582-56111:+ | gene-YEL052W_Sparadoxus | rna-NM_001178867.1_Sparadoxus | cds-NP_010862.1_Sparadoxus | 91.4 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |