ADK2 (YER170W)


Gene profile

Gene name: ADK2
Reference locus (S288C): YER170W
Gene biotype: protein_coding

Description: GTP:AMP phosphotransferase, mitochondrial; Mitochondrial adenylate kinase; catalyzes the reversible synthesis of GTP and AMP from GDP and ADP; may serve as a back-up for synthesizing GTP or ADP depending on metabolic conditions; 3' sequence of ADK2 varies with strain background

Top 10 interactors (score): YNK1 (0.969); ADO1 (0.958); APT2 (0.949); APT1 (0.949); ADE13 (0.933); AMD1 (0.93); FAP7 (0.929); PYK2 (0.924); CDC19 (0.924); RNR1 (0.92); YND1 (0.901); PDE2 (0.901); RNR2 (0.901); THI80 (0.901); RNR4 (0.901); PDE1 (0.9); ADK1 (0.837); RNR3 (0.72); RTC6 (0.714); RPS3 (0.691)

Homologues (species, bitscore): AK3 (Homo sapiens, 176.8); Ak3 (Mus musculus, 188.0); ak3 (Danio rerio, 196.4); ak3 (Xenopus tropicalis, 183.3); Adk3 (Drosophila melanogaster, 183.7); let-754 (Caenorhabditis elegans, 167.2); At5g63400 (Arabidopsis thaliana, 164.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005299.1:507495-508173:+ gene-YER170W_AKU4011 rna-NM_001179060.3_AKU4011 cds-NP_011097.3_AKU4011 99.7 100.0 Verified 1 1 0 False False False True False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000176.1:25191-25869:- gene-YER170W_BG1 rna-NM_001179060.3_BG1 cds-NP_011097.3_BG1 99.7 100.0 Verified 1 1 0 False False False True False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005507.1:520237-520915:+ gene-YER170W_Bruggeman rna-NM_001179060.3_Bruggeman cds-NP_011097.3_Bruggeman 99.8 100.0 Verified 1 1 0 False False False True False
CAT1 GCA_001738705.1 Bioethanol South America CM005523.1:506829-507507:+ gene-YER170W_CAT1 rna-NM_001179060.3_CAT1 cds-NP_011097.3_CAT1 99.8 100.0 Verified 1 1 0 False False False True False
CBS1585 GCA_001738375.1 Sake Asia CM005363.1:507302-507980:+ gene-YER170W_CBS1585 rna-NM_001179060.3_CBS1585 cds-NP_011097.3_CBS1585 99.7 100.0 Verified 1 1 0 False False False True False
CBS436 GCA_001738355.1 Sake Asia CM005347.1:517197-517875:+ gene-YER170W_CBS436 rna-NM_001179060.3_CBS436 cds-NP_011097.3_CBS436 99.7 100.0 Mismatch 1 1 0 False False False True False
CBS6412 GCA_001738345.1 Sake Asia CM005331.1:505279-505957:+ gene-YER170W_CBS6412 rna-NM_001179060.3_CBS6412 cds-NP_011097.3_CBS6412 99.7 100.0 Mismatch 1 1 0 False False False True False
CBS6413 GCA_001738265.1 Sake Asia CM005315.1:513848-514526:+ gene-YER170W_CBS6413 rna-NM_001179060.3_CBS6413 cds-NP_011097.3_CBS6413 99.7 100.0 Verified 1 1 0 False False False True False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001526.1:523743-524420:+ gene-YER170W_CENPK1137D rna-NM_001179060.3_CENPK1137D cds-NP_011097.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005475.1:513469-514147:+ gene-YER170W_EthanolRed rna-NM_001179060.3_EthanolRed cds-NP_011097.3_EthanolRed 99.8 100.0 Verified 1 1 0 False False False True False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005539.1:514405-515083:+ gene-YER170W_FaliES1 rna-NM_001179060.3_FaliES1 cds-NP_011097.3_FaliES1 99.8 100.0 Verified 1 1 0 False False False True False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000169.1:24823-25501:- gene-YER170W_JAY291 rna-NM_001179060.3_JAY291 cds-NP_011097.3_JAY291 99.7 100.0 Verified 1 1 0 False False False True False
MUCL30387 GCA_001738515.1 Bread Europe CM005411.1:507552-508230:+ gene-YER170W_MUCL30387 rna-NM_001179060.3_MUCL30387 cds-NP_011097.3_MUCL30387 99.8 100.0 Verified 1 1 0 False False False True False
MUCL30388 GCA_001738495.1 Bread Europe CM005443.1:510468-511146:+ gene-YER170W_MUCL30388 rna-NM_001179060.3_MUCL30388 cds-NP_011097.3_MUCL30388 99.8 100.0 Verified 1 1 0 False False False True False
MUCL39482 GCA_001738235.1 Sake Asia CM005283.1:503260-503938:+ gene-YER170W_MUCL39482 rna-NM_001179060.3_MUCL39482 cds-NP_011097.3_MUCL39482 99.7 100.0 Verified 1 1 0 False False False True False
MUCL42920 GCA_001738485.1 Bread Europe CM005427.1:517784-518462:+ gene-YER170W_MUCL42920 rna-NM_001179060.3_MUCL42920 cds-NP_011097.3_MUCL42920 99.8 100.0 Verified 1 1 0 False False False True False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011814.1:525973-526650:+ gene-YER170W_NCIM3186 rna-NM_001179060.3_NCIM3186 cds-NP_011097.3_NCIM3186 99.7 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005267.1:512715-513393:+ gene-YER170W_NCYC1407 rna-NM_001179060.3_NCYC1407 cds-NP_011097.3_NCYC1407 99.5 100.0 Verified 1 1 0 False False False True False
PE2H3 GCA_905220325.1 Bioethanol South America HG994144.1:528648-529326:+ gene-YER170W_PE2H3 rna-NM_001179060.3_PE2H3 cds-NP_011097.3_PE2H3 99.7 100.0 Verified 1 1 0 False False False True False
PE2H4 GCA_905220315.1 Bioethanol South America LR999876.1:518589-519267:+ gene-YER170W_PE2H4 rna-NM_001179060.3_PE2H4 cds-NP_011097.3_PE2H4 99.7 100.0 Verified 1 1 0 False False False True False
S288C GCF_000146045.2 Laboratory Not applicable NC_001137.3:525974-526651:+ gene-YER170W_S288C rna-NM_001179060.3_S288C cds-NP_011097.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000030.1:78126-78804:+ gene-YER170W_SA1 rna-NM_001179060.3_SA1 cds-NP_011097.3_SA1 99.7 100.0 Verified 1 1 0 False False False True False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005491.1:515205-515883:+ gene-YER170W_ThermosaccDry rna-NM_001179060.3_ThermosaccDry cds-NP_011097.3_ThermosaccDry 99.8 100.0 Verified 1 1 0 False False False True False
VR1 GCA_001738595.1 Bioethanol South America CM005459.1:508494-509172:+ gene-YER170W_VR1 rna-NM_001179060.3_VR1 cds-NP_011097.3_VR1 99.7 100.0 Verified 1 1 0 False False False True False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000011.1:28052-28730:+ gene-YER170W_ZTW1 rna-NM_001179060.3_ZTW1 cds-NP_011097.3_ZTW1 99.7 100.0 Verified 1 1 0 False False False True False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047491.1:516423-517101:+ gene-YER170W_Sparadoxus rna-NM_001179060.3_Sparadoxus cds-NP_011097.3_Sparadoxus 88.8 100.0 Verified 1 1 0 False False False True False

Additional files