Gene name: ADI1
Reference locus (S288C): YMR009W
Gene biotype: protein_coding
Description: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Acireductone dioxygenease involved in methionine salvage pathway; transcribed as polycistronic mRNA with YMR010W and regulated post-transcriptionally by RNase III (Rnt1p) cleavage; ADI1 mRNA is induced in heat shock conditions; human ortholog ADI1 can complement yeast adi1 mutant; Belongs to the acireductone dioxygenase (ARD) family
Top 10 interactors (score): UTR4 (0.993); MEU1 (0.99); MDE1 (0.981); MRI1 (0.955); ARO8 (0.932); YNL010W (0.888); BAT2 (0.881); BAT1 (0.835); TAD1 (0.78); MRPL27 (0.714); PCM1 (0.712); ECM32 (0.695); RBK1 (0.694); ARX1 (0.687); TRP5 (0.679); RIA1 (0.651); SPE2 (0.648); MPD2 (0.614); PNP1 (0.607); PUT1 (0.574)
Homologues (species, bitscore): ADI1 (Homo sapiens, 145.6); Adi1 (Mus musculus, 142.5); adi1 (Danio rerio, 129.8); adi1 (Xenopus tropicalis, 131.7); CG32068 (Drosophila melanogaster, 119.4); F42F12.4 (Caenorhabditis elegans, 114.4); ARD4 (Arabidopsis thaliana, 143.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:333718-334257:+ | gene-YMR009W_AKU4011 | rna-NM_001182505.1_AKU4011 | cds-NP_013722.1_AKU4011 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000201.1:208612-209151:- | gene-YMR009W_BG1 | rna-NM_001182505.1_BG1 | cds-NP_013722.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:273666-274205:+ | gene-YMR009W_Bruggeman | rna-NM_001182505.1_Bruggeman | cds-NP_013722.1_Bruggeman | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:276156-276695:+ | gene-YMR009W_CAT1 | rna-NM_001182505.1_CAT1 | cds-NP_013722.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:266659-267198:+ | gene-YMR009W_CBS1585 | rna-NM_001182505.1_CBS1585 | cds-NP_013722.1_CBS1585 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:272185-272724:+ | gene-YMR009W_CBS436 | rna-NM_001182505.1_CBS436 | cds-NP_013722.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:380063-380602:+ | gene-YMR009W_CBS6412 | rna-NM_001182505.1_CBS6412 | cds-NP_013722.1_CBS6412 | 98.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:265915-266454:+ | gene-YMR009W_CBS6413 | rna-NM_001182505.1_CBS6413 | cds-NP_013722.1_CBS6413 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:278832-279371:+ | gene-YMR009W_CENPK1137D | rna-NM_001182505.1_CENPK1137D | cds-NP_013722.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005483.1:266467-267006:+ | gene-YMR009W_EthanolRed | rna-NM_001182505.1_EthanolRed | cds-NP_013722.1_EthanolRed | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:269649-270188:+ | gene-YMR009W_FaliES1 | rna-NM_001182505.1_FaliES1 | cds-NP_013722.1_FaliES1 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000033.1:166744-167283:- | gene-YMR009W_JAY291 | rna-NM_001182505.1_JAY291 | cds-NP_013722.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:271377-271916:+ | gene-YMR009W_MUCL30387 | rna-NM_001182505.1_MUCL30387 | cds-NP_013722.1_MUCL30387 | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:276052-276591:+ | gene-YMR009W_MUCL30388 | rna-NM_001182505.1_MUCL30388 | cds-NP_013722.1_MUCL30388 | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:266944-267483:+ | gene-YMR009W_MUCL39482 | rna-NM_001182505.1_MUCL39482 | cds-NP_013722.1_MUCL39482 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:272736-273275:+ | gene-YMR009W_MUCL42920 | rna-NM_001182505.1_MUCL42920 | cds-NP_013722.1_MUCL42920 | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:284056-284595:+ | gene-YMR009W_NCIM3186 | rna-NM_001182505.1_NCIM3186 | cds-NP_013722.1_NCIM3186 | 97.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:266861-267400:+ | gene-YMR009W_NCYC1407 | rna-NM_001182505.1_NCYC1407 | cds-NP_013722.1_NCYC1407 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:272790-273329:+ | gene-YMR009W_PE2H3 | rna-NM_001182505.1_PE2H3 | cds-NP_013722.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:278885-279424:+ | gene-YMR009W_PE2H4 | rna-NM_001182505.1_PE2H4 | cds-NP_013722.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:284102-284641:+ | gene-YMR009W_S288C | rna-NM_001182505.1_S288C | cds-NP_013722.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000005.1:253631-254170:- | gene-YMR009W_SA1 | rna-NM_001182505.1_SA1 | cds-NP_013722.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:266718-267257:+ | gene-YMR009W_ThermosaccDry | rna-NM_001182505.1_ThermosaccDry | cds-NP_013722.1_ThermosaccDry | 98.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:270676-271215:+ | gene-YMR009W_VR1 | rna-NM_001182505.1_VR1 | cds-NP_013722.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000027.1:245771-246310:+ | gene-YMR009W_ZTW1 | rna-NM_001182505.1_ZTW1 | cds-NP_013722.1_ZTW1 | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:278211-278750:+ | gene-YMR009W_Sparadoxus | rna-NM_001182505.1_Sparadoxus | cds-NP_013722.1_Sparadoxus | 88.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |