ADH6 (YMR318C)


Gene profile

Gene name: ADH6
Reference locus (S288C): YMR318C
Gene biotype: protein_coding

Description: NADPH-dependent medium chain alcohol dehydrogenase; has broad substrate specificity; member of the cinnamyl family of alcohol dehydrogenases; may be involved in fusel alcohol synthesis or in aldehyde tolerance; protein abundance increases in response to DNA replication stress

Top 10 interactors (score): ADH7 (0.983); PDC6 (0.948); PDC1 (0.938); THI3 (0.931); GCY1 (0.915); GPP2 (0.914); PDC5 (0.907); GUT1 (0.903); ALD6 (0.902); YJU3 (0.901); GPP1 (0.9); ALD2 (0.856); ALD4 (0.852); YDL177C (0.848); ALD3 (0.827); YNL134C (0.81); HFD1 (0.794); ALD5 (0.788); ARI1 (0.768); ZWF1 (0.747)

Homologues (species, bitscore): ADH7 (Homo sapiens, 70.1); Adh5 (Mus musculus, 65.9); LOC570613 (Danio rerio, 71.2); adh5 (Xenopus tropicalis, 72.8); Sodh-2 (Drosophila melanogaster, 91.3); sodh-1 (Caenorhabditis elegans, 125.2); ELI3-2 (Arabidopsis thaliana, 214.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005307.1:950537-951619:- gene-YMR318C_AKU4011 rna-NM_001182831.3_AKU4011 cds-NP_014051.3_AKU4011 100.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000069.1:2704-3786:+ gene-YMR318C_BG1 rna-NM_001182831.3_BG1 cds-NP_014051.3_BG1 99.1 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005515.1:895659-896741:- gene-YMR318C_Bruggeman rna-NM_001182831.3_Bruggeman cds-NP_014051.3_Bruggeman 99.5 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005531.1:898417-899499:- gene-YMR318C_CAT1 rna-NM_001182831.3_CAT1 cds-NP_014051.3_CAT1 99.1 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005371.1:882838-883920:- gene-YMR318C_CBS1585 rna-NM_001182831.3_CBS1585 cds-NP_014051.3_CBS1585 100.0 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005355.1:905230-906312:- gene-YMR318C_CBS436 rna-NM_001182831.3_CBS436 cds-NP_014051.3_CBS436 99.7 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005339.1:993749-994831:- gene-YMR318C_CBS6412 rna-NM_001182831.3_CBS6412 cds-NP_014051.3_CBS6412 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005323.1:882019-883101:- gene-YMR318C_CBS6413 rna-NM_001182831.3_CBS6413 cds-NP_014051.3_CBS6413 100.0 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001534.1:905504-906586:- gene-YMR318C_CENPK1137D rna-NM_001182831.3_CENPK1137D cds-NP_014051.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:942558-943640:- gene-YMR318C_EthanolRed rna-NM_001182831.3_EthanolRed cds-NP_014051.3_EthanolRed 99.9 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005547.1:888808-889890:- gene-YMR318C_FaliES1 rna-NM_001182831.3_FaliES1 cds-NP_014051.3_FaliES1 99.9 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000096.1:5460-6542:+ gene-YMR318C_JAY291 rna-NM_001182831.3_JAY291 cds-NP_014051.3_JAY291 99.7 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005419.1:888637-889719:- gene-YMR318C_MUCL30387 rna-NM_001182831.3_MUCL30387 cds-NP_014051.3_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005451.1:898367-899449:- gene-YMR318C_MUCL30388 rna-NM_001182831.3_MUCL30388 cds-NP_014051.3_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005291.1:883865-884947:- gene-YMR318C_MUCL39482 rna-NM_001182831.3_MUCL39482 cds-NP_014051.3_MUCL39482 100.0 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005435.1:892400-893482:- gene-YMR318C_MUCL42920 rna-NM_001182831.3_MUCL42920 cds-NP_014051.3_MUCL42920 99.5 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011822.1:911015-912097:- gene-YMR318C_NCIM3186 rna-NM_001182831.3_NCIM3186 cds-NP_014051.3_NCIM3186 99.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005275.1:883619-884701:- gene-YMR318C_NCYC1407 rna-NM_001182831.3_NCYC1407 cds-NP_014051.3_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994152.1:898929-900011:- gene-YMR318C_PE2H3 rna-NM_001182831.3_PE2H3 cds-NP_014051.3_PE2H3 99.7 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999884.1:894757-895839:- gene-YMR318C_PE2H4 rna-NM_001182831.3_PE2H4 cds-NP_014051.3_PE2H4 99.1 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001145.3:911061-912143:- gene-YMR318C_S288C rna-NM_001182831.3_S288C cds-NP_014051.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000036.1:88661-89743:- gene-YMR318C_SA1 rna-NM_001182831.3_SA1 cds-NP_014051.3_SA1 99.1 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005499.1:884963-886045:- gene-YMR318C_ThermosaccDry rna-NM_001182831.3_ThermosaccDry cds-NP_014051.3_ThermosaccDry 99.9 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005467.1:898554-899636:- gene-YMR318C_VR1 rna-NM_001182831.3_VR1 cds-NP_014051.3_VR1 99.1 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000028.1:299900-300982:- gene-YMR318C_ZTW1 rna-NM_001182831.3_ZTW1 cds-NP_014051.3_ZTW1 99.8 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047499.1:903681-904763:- gene-YMR318C_Sparadoxus rna-NM_001182831.3_Sparadoxus cds-NP_014051.3_Sparadoxus 89.2 100.0 Verified 1 1 1 False True False False False

Additional files