Gene name: ADH4
Reference locus (S288C): YGL256W
Gene biotype: protein_coding
Description: Alcohol dehydrogenase isoenzyme type IV; dimeric enzyme demonstrated to be zinc-dependent despite sequence similarity to iron-activated alcohol dehydrogenases; transcription is induced in response to zinc deficiency
Top 10 interactors (score): SFA1 (0.998); PRM15 (0.988); PDC6 (0.977); ADO1 (0.974); PDC5 (0.972); ADH3 (0.968); ADH2 (0.968); ADH1 (0.967); RKI1 (0.963); APE4 (0.962); SAH1 (0.962); ADE12 (0.962); COF1 (0.96); PDC1 (0.958); VEL1 (0.956); YOR387C (0.946); ARO10 (0.942); THI3 (0.923); ALD6 (0.905); ALD3 (0.902)
Homologues (species, bitscore): ADHFE1 (Homo sapiens, 103.6); Adhfe1 (Mus musculus, 107.1); adhfe1 (Danio rerio, 107.5); adhfe1 (Xenopus tropicalis, 110.2); T3dh (Drosophila melanogaster, 110.5); Y38F1A.6 (Caenorhabditis elegans, 122.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:16664-17812:+ | gene-YGL256W_AKU4011 | rna-NM_001181122.1_AKU4011 | cds-NP_011258.2_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000175.1:8708-9856:+ | gene-YGL256W_BG1 | rna-NM_001181122.1_BG1 | cds-NP_011258.2_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:16531-17679:+ | gene-YGL256W_Bruggeman | rna-NM_001181122.1_Bruggeman | cds-NP_011258.2_Bruggeman | 98.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:15096-16244:+ | gene-YGL256W_CAT1 | rna-NM_001181122.1_CAT1 | cds-NP_011258.2_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:20952-22100:+ | gene-YGL256W_CBS1585 | rna-NM_001181122.1_CBS1585 | cds-NP_011258.2_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:15693-16841:+ | gene-YGL256W_CBS436 | rna-NM_001181122.1_CBS436 | cds-NP_011258.2_CBS436 | 98.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:8520-9668:+ | gene-YGL256W_CBS6412 | rna-NM_001181122.1_CBS6412 | cds-NP_011258.2_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:14807-15955:+ | gene-YGL256W_CBS6413 | rna-NM_001181122.1_CBS6413 | cds-NP_011258.2_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:14812-15960:+ | gene-YGL256W_CENPK1137D | rna-NM_001181122.1_CENPK1137D | cds-NP_011258.2_CENPK1137D | 98.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:7940-9088:+ | gene-YGL256W_EthanolRed | rna-NM_001181122.1_EthanolRed | cds-NP_011258.2_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:8301-9449:+ | gene-YGL256W_FaliES1 | rna-NM_001181122.1_FaliES1 | cds-NP_011258.2_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000079.1:57608-58756:- | gene-YGL256W_JAY291 | rna-NM_001181122.1_JAY291 | cds-NP_011258.2_JAY291 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:16716-17864:+ | gene-YGL256W_MUCL30387 | rna-NM_001181122.1_MUCL30387 | cds-NP_011258.2_MUCL30387 | 98.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:18625-19773:+ | gene-YGL256W_MUCL30388 | rna-NM_001181122.1_MUCL30388 | cds-NP_011258.2_MUCL30388 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:17549-18697:+ | gene-YGL256W_MUCL39482 | rna-NM_001181122.1_MUCL39482 | cds-NP_011258.2_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:18101-19249:+ | gene-YGL256W_MUCL42920 | rna-NM_001181122.1_MUCL42920 | cds-NP_011258.2_MUCL42920 | 98.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:15159-16307:+ | gene-YGL256W_NCIM3186 | rna-NM_001181122.1_NCIM3186 | cds-NP_011258.2_NCIM3186 | 98.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:9312-10460:+ | gene-YGL256W_NCYC1407 | rna-NM_001181122.1_NCYC1407 | cds-NP_011258.2_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:11183-12331:+ | gene-YGL256W_PE2H3 | rna-NM_001181122.1_PE2H3 | cds-NP_011258.2_PE2H3 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:10731-11879:+ | gene-YGL256W_PE2H4 | rna-NM_001181122.1_PE2H4 | cds-NP_011258.2_PE2H4 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:15159-16307:+ | gene-YGL256W_S288C | rna-NM_001181122.1_S288C | cds-NP_011258.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000002.1:359042-360190:- | gene-YGL256W_SA1 | rna-NM_001181122.1_SA1 | cds-NP_011258.2_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:8616-9764:+ | gene-YGL256W_ThermosaccDry | rna-NM_001181122.1_ThermosaccDry | cds-NP_011258.2_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:15619-16767:+ | gene-YGL256W_VR1 | rna-NM_001181122.1_VR1 | cds-NP_011258.2_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:7662-8810:+ | gene-YGL256W_ZTW1 | rna-NM_001181122.1_ZTW1 | cds-NP_011258.2_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:16324-17472:+ | gene-YGL256W_Sparadoxus | rna-NM_001181122.1_Sparadoxus | cds-NP_011258.2_Sparadoxus | 95.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |