Gene name: ADH1
Reference locus (S288C): YOL086C
Gene biotype: protein_coding
Description: Alcohol dehydrogenase; fermentative isozyme active as homo- or heterotetramers; required for the reduction of acetaldehyde to ethanol, the last step in the glycolytic pathway; ADH1 has a paralog, ADH5, that arose from the whole genome duplication
Top 10 interactors (score): PDC1 (0.998); PGK1 (0.993); CDC19 (0.987); FBA1 (0.986); TPI1 (0.985); ENO2 (0.985); ENO1 (0.984); TDH3 (0.981); PDC5 (0.981); GPM1 (0.972); PDC6 (0.972); ADH4 (0.967); TDH2 (0.965); ARO10 (0.956); PGI1 (0.929); ALD6 (0.918); TEF1 (0.917); THI3 (0.91); TDH1 (0.907); URA3 (0.89)
Homologues (species, bitscore): ADH1B (Homo sapiens, 93.6); Adh1 (Mus musculus, 92.4); adh5 (Danio rerio, 88.2); ADH9 (Xenopus tropicalis, 95.9); Fdh (Drosophila melanogaster, 97.8); sodh-1 (Caenorhabditis elegans, 335.1); CAD6 (Arabidopsis thaliana, 147.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:142897-144189:- | gene-YOL086C_AKU4011 | rna-NM_001183340.1_AKU4011 | cds-NP_014555.1_AKU4011 | 79.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000172.1:107999-109045:- | gene-YOL086C_BG1 | rna-NM_001183340.1_BG1 | cds-NP_014555.1_BG1 | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:144443-145489:- | gene-YOL086C_Bruggeman | rna-NM_001183340.1_Bruggeman | cds-NP_014555.1_Bruggeman | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:143775-144821:- | gene-YOL086C_CAT1 | rna-NM_001183340.1_CAT1 | cds-NP_014555.1_CAT1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:137307-138599:- | gene-YOL086C_CBS1585 | rna-NM_001183340.1_CBS1585 | cds-NP_014555.1_CBS1585 | 79.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:142580-143815:- | gene-YOL086C_CBS436 | rna-NM_001183340.1_CBS436 | cds-NP_014555.1_CBS436 | 83.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:137465-138504:- | gene-YOL086C_CBS6412 | rna-NM_001183340.1_CBS6412 | cds-NP_014555.1_CBS6412 | 98.2 | 99.3 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:144170-145462:- | gene-YOL086C_CBS6413 | rna-NM_001183340.1_CBS6413 | cds-NP_014555.1_CBS6413 | 79.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:153513-154559:- | gene-YOL086C_CENPK1137D | rna-NM_001183340.1_CENPK1137D | cds-NP_014555.1_CENPK1137D | 55.3 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:140469-141515:- | gene-YOL086C_EthanolRed | rna-NM_001183340.1_EthanolRed | cds-NP_014555.1_EthanolRed | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:142796-143842:- | gene-YOL086C_FaliES1 | rna-NM_001183340.1_FaliES1 | cds-NP_014555.1_FaliES1 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000160.1:1-680:+ | gene-YOL086C_JAY291 | rna-NM_001183340.1_JAY291 | cds-NP_014555.1_JAY291 | 64.0 | 64.9 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:148645-149691:- | gene-YOL086C_MUCL30387 | rna-NM_001183340.1_MUCL30387 | cds-NP_014555.1_MUCL30387 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:151826-153370:- | gene-YOL086C_MUCL30388 | rna-NM_001183340.1_MUCL30388 | cds-NP_014555.1_MUCL30388 | 66.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:145228-146520:- | gene-YOL086C_MUCL39482 | rna-NM_001183340.1_MUCL39482 | cds-NP_014555.1_MUCL39482 | 79.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:160995-162041:- | gene-YOL086C_MUCL42920 | rna-NM_001183340.1_MUCL42920 | cds-NP_014555.1_MUCL42920 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:159437-160483:- | gene-YOL086C_NCIM3186 | rna-NM_001183340.1_NCIM3186 | cds-NP_014555.1_NCIM3186 | 98.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:151825-153117:- | gene-YOL086C_NCYC1407 | rna-NM_001183340.1_NCYC1407 | cds-NP_014555.1_NCYC1407 | 79.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:135117-136163:- | gene-YOL086C_PE2H3 | rna-NM_001183340.1_PE2H3 | cds-NP_014555.1_PE2H3 | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:146106-147152:- | gene-YOL086C_PE2H4 | rna-NM_001183340.1_PE2H4 | cds-NP_014555.1_PE2H4 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:159548-160594:- | gene-YOL086C_S288C | rna-NM_001183340.1_S288C | cds-NP_014555.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000001.1:127429-128475:- | gene-YOL086C_SA1 | rna-NM_001183340.1_SA1 | cds-NP_014555.1_SA1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:141804-142850:- | gene-YOL086C_ThermosaccDry | rna-NM_001183340.1_ThermosaccDry | cds-NP_014555.1_ThermosaccDry | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:142373-143419:- | gene-YOL086C_VR1 | rna-NM_001183340.1_VR1 | cds-NP_014555.1_VR1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000031.1:141501-142547:- | gene-YOL086C_ZTW1 | rna-NM_001183340.1_ZTW1 | cds-NP_014555.1_ZTW1 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:144973-146019:- | gene-YOL086C_Sparadoxus | rna-NM_001183340.1_Sparadoxus | cds-NP_014555.1_Sparadoxus | 97.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |