ADE8 (YDR408C)


Gene profile

Gene name: ADE8
Reference locus (S288C): YDR408C
Gene biotype: protein_coding

Description: Phosphoribosylglycinamide formyltransferase; Phosphoribosyl-glycinamide transformylase; catalyzes a step in the 'de novo' purine nucleotide biosynthetic pathway

Top 10 interactors (score): ADE5,7 (0.999); ADE16 (0.999); ADE6 (0.999); ADE17 (0.999); ADE4 (0.998); ADE3 (0.996); ADE2 (0.996); ADE1 (0.995); MIS1 (0.986); DFR1 (0.982); SHM2 (0.978); GCV1 (0.978); MTD1 (0.977); SHM1 (0.974); ADE13 (0.972); FAU1 (0.972); FMT1 (0.953); ADE12 (0.92); HIS3 (0.914); RPL3 (0.907)

Homologues (species, bitscore): GART (Homo sapiens, 89.7); Gart (Mus musculus, 95.1); gart (Xenopus tropicalis, 82.0); ade3 (Drosophila melanogaster, 95.5); F38B6.4 (Caenorhabditis elegans, 81.6); AT1G31220 (Arabidopsis thaliana, 60.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:1228367-1229011:- gene-YDR408C_AKU4011 rna-NM_001180716.3_AKU4011 cds-NP_010696.3_AKU4011 99.6 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000039.1:106851-107495:- gene-YDR408C_BG1 rna-NM_001180716.3_BG1 cds-NP_010696.3_BG1 99.8 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:1259246-1259890:- gene-YDR408C_Bruggeman rna-NM_001180716.3_Bruggeman cds-NP_010696.3_Bruggeman 99.8 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:1237809-1238453:- gene-YDR408C_CAT1 rna-NM_001180716.3_CAT1 cds-NP_010696.3_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:1223287-1223931:- gene-YDR408C_CBS1585 rna-NM_001180716.3_CBS1585 cds-NP_010696.3_CBS1585 99.6 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:1242147-1242791:- gene-YDR408C_CBS436 rna-NM_001180716.3_CBS436 cds-NP_010696.3_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:1219341-1219985:- gene-YDR408C_CBS6412 rna-NM_001180716.3_CBS6412 cds-NP_010696.3_CBS6412 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:1241196-1241840:- gene-YDR408C_CBS6413 rna-NM_001180716.3_CBS6413 cds-NP_010696.3_CBS6413 99.6 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:1286874-1287518:- gene-YDR408C_CENPK1137D rna-NM_001180716.3_CENPK1137D cds-NP_010696.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:1232769-1233413:- gene-YDR408C_EthanolRed rna-NM_001180716.3_EthanolRed cds-NP_010696.3_EthanolRed 99.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:1236079-1236723:- gene-YDR408C_FaliES1 rna-NM_001180716.3_FaliES1 cds-NP_010696.3_FaliES1 99.6 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000181.1:18806-19450:+ gene-YDR408C_JAY291 rna-NM_001180716.3_JAY291 cds-NP_010696.3_JAY291 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:1242808-1243452:- gene-YDR408C_MUCL30387 rna-NM_001180716.3_MUCL30387 cds-NP_010696.3_MUCL30387 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:1224914-1225558:- gene-YDR408C_MUCL30388 rna-NM_001180716.3_MUCL30388 cds-NP_010696.3_MUCL30388 99.8 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:1214615-1215259:- gene-YDR408C_MUCL39482 rna-NM_001180716.3_MUCL39482 cds-NP_010696.3_MUCL39482 99.6 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:1157047-1157691:- gene-YDR408C_MUCL42920 rna-NM_001180716.3_MUCL42920 cds-NP_010696.3_MUCL42920 99.8 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:1288138-1288782:- gene-YDR408C_NCIM3186 rna-NM_001180716.3_NCIM3186 cds-NP_010696.3_NCIM3186 99.8 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:1228587-1229231:- gene-YDR408C_NCYC1407 rna-NM_001180716.3_NCYC1407 cds-NP_010696.3_NCYC1407 99.6 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:1238720-1239364:- gene-YDR408C_PE2H3 rna-NM_001180716.3_PE2H3 cds-NP_010696.3_PE2H3 99.8 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:1244288-1244932:- gene-YDR408C_PE2H4 rna-NM_001180716.3_PE2H4 cds-NP_010696.3_PE2H4 99.8 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:1288215-1288859:- gene-YDR408C_S288C rna-NM_001180716.3_S288C cds-NP_010696.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000071.1:18928-19572:+ gene-YDR408C_SA1 rna-NM_001180716.3_SA1 cds-NP_010696.3_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:1240341-1240985:- gene-YDR408C_ThermosaccDry rna-NM_001180716.3_ThermosaccDry cds-NP_010696.3_ThermosaccDry 99.6 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:1255527-1256171:- gene-YDR408C_VR1 rna-NM_001180716.3_VR1 cds-NP_010696.3_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000008.1:283136-283780:- gene-YDR408C_ZTW1 rna-NM_001180716.3_ZTW1 cds-NP_010696.3_ZTW1 99.6 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:1235580-1236224:- gene-YDR408C_Sparadoxus rna-NM_001180716.3_Sparadoxus cds-NP_010696.3_Sparadoxus 90.8 100.0 Verified 1 1 1 False True False False False

Additional files