ADE6 (YGR061C)


Gene profile

Gene name: ADE6
Reference locus (S288C): YGR061C
Gene biotype: protein_coding

Description: Phosphoribosylformylglycinamidine synthase; Formylglycinamidine-ribonucleotide (FGAM)-synthetase; catalyzes a step in the 'de novo' purine nucleotide biosynthetic pathway

Top 10 interactors (score): ADE8 (0.999); ADE5,7 (0.999); ADE4 (0.999); ADE17 (0.992); ADE1 (0.99); ADE16 (0.989); ADE2 (0.983); URA2 (0.975); GUA1 (0.972); ADE13 (0.967); HIS4 (0.959); CPA2 (0.957); TRP3 (0.934); LYS2 (0.933); URA4 (0.913); LYS4 (0.906); CWC2 (0.9); TRP1 (0.89); ADE12 (0.888); HIS7 (0.881)

Homologues (species, bitscore): PFAS (Homo sapiens, 688.7); Pfas (Mus musculus, 703.0); pfas (Danio rerio, 701.8); pfas (Xenopus tropicalis, 702.6); ade2 (Drosophila melanogaster, 654.1); F10F2.2 (Caenorhabditis elegans, 629.8); PUR4 (Arabidopsis thaliana, 775.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005301.1:595581-599657:- gene-YGR061C_AKU4011 rna-NM_001181190.1_AKU4011 cds-NP_011575.1_AKU4011 99.7 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000173.1:31909-35985:- gene-YGR061C_BG1 rna-NM_001181190.1_BG1 cds-NP_011575.1_BG1 99.9 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005509.1:597868-601944:- gene-YGR061C_Bruggeman rna-NM_001181190.1_Bruggeman cds-NP_011575.1_Bruggeman 99.7 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005525.1:596295-600371:- gene-YGR061C_CAT1 rna-NM_001181190.1_CAT1 cds-NP_011575.1_CAT1 99.9 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005365.1:596895-600971:- gene-YGR061C_CBS1585 rna-NM_001181190.1_CBS1585 cds-NP_011575.1_CBS1585 99.6 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005349.1:598191-602267:- gene-YGR061C_CBS436 rna-NM_001181190.1_CBS436 cds-NP_011575.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005333.1:589690-593766:- gene-YGR061C_CBS6412 rna-NM_001181190.1_CBS6412 cds-NP_011575.1_CBS6412 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005317.1:593688-597764:- gene-YGR061C_CBS6413 rna-NM_001181190.1_CBS6413 cds-NP_011575.1_CBS6413 99.6 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001528.1:611607-615683:- gene-YGR061C_CENPK1137D rna-NM_001181190.1_CENPK1137D cds-NP_011575.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005477.1:583824-587900:- gene-YGR061C_EthanolRed rna-NM_001181190.1_EthanolRed cds-NP_011575.1_EthanolRed 99.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005541.1:587303-591379:- gene-YGR061C_FaliES1 rna-NM_001181190.1_FaliES1 cds-NP_011575.1_FaliES1 99.6 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000435.1:38250-42326:- gene-YGR061C_JAY291 rna-NM_001181190.1_JAY291 cds-NP_011575.1_JAY291 99.9 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005413.1:594501-598577:- gene-YGR061C_MUCL30387 rna-NM_001181190.1_MUCL30387 cds-NP_011575.1_MUCL30387 99.9 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005445.1:597898-601974:- gene-YGR061C_MUCL30388 rna-NM_001181190.1_MUCL30388 cds-NP_011575.1_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005285.1:592732-596808:- gene-YGR061C_MUCL39482 rna-NM_001181190.1_MUCL39482 cds-NP_011575.1_MUCL39482 99.6 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005429.1:602526-606602:- gene-YGR061C_MUCL42920 rna-NM_001181190.1_MUCL42920 cds-NP_011575.1_MUCL42920 99.9 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011816.1:611889-615965:- gene-YGR061C_NCIM3186 rna-NM_001181190.1_NCIM3186 cds-NP_011575.1_NCIM3186 99.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005269.1:586910-590986:- gene-YGR061C_NCYC1407 rna-NM_001181190.1_NCYC1407 cds-NP_011575.1_NCYC1407 99.6 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994146.1:590155-594231:- gene-YGR061C_PE2H3 rna-NM_001181190.1_PE2H3 cds-NP_011575.1_PE2H3 99.9 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999878.1:595262-599338:- gene-YGR061C_PE2H4 rna-NM_001181190.1_PE2H4 cds-NP_011575.1_PE2H4 99.9 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001139.9:611889-615965:- gene-YGR061C_S288C rna-NM_001181190.1_S288C cds-NP_011575.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000015.1:38354-42430:- gene-YGR061C_SA1 rna-NM_001181190.1_SA1 cds-NP_011575.1_SA1 99.9 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005493.1:606641-610717:- gene-YGR061C_ThermosaccDry rna-NM_001181190.1_ThermosaccDry cds-NP_011575.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005461.1:703576-707652:- gene-YGR061C_VR1 rna-NM_001181190.1_VR1 cds-NP_011575.1_VR1 99.9 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000015.1:62110-66186:- gene-YGR061C_ZTW1 rna-NM_001181190.1_ZTW1 cds-NP_011575.1_ZTW1 99.7 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047493.1:597090-601166:- gene-YGR061C_Sparadoxus rna-NM_001181190.1_Sparadoxus cds-NP_011575.1_Sparadoxus 91.9 100.0 Verified 1 1 1 False True False False False

Additional files