Gene name: ADE5,7
Reference locus (S288C): YGL234W
Gene biotype: protein_coding
Description: Phosphoribosylamine--glycine ligase / phosphoribosylformylglycinamidine cyclo-ligase; Bifunctional purine biosynthetic protein ADE5,7; Enzyme of the 'de novo' purine nucleotide biosynthetic pathway; contains aminoimidazole ribotide synthetase and glycinamide ribotide synthetase activities; In the C-terminal section; belongs to the AIR synthase family
Top 10 interactors (score): ADE2 (0.999); ADE6 (0.999); ADE8 (0.999); ADE1 (0.999); ADE4 (0.999); ADE17 (0.997); ADE13 (0.996); ADE16 (0.994); HIS7 (0.976); SHM2 (0.97); ADE3 (0.966); ADE12 (0.95); RPL3 (0.938); HIS4 (0.917); URA3 (0.909); MTD1 (0.895); GUA1 (0.894); MIS1 (0.892); LYS2 (0.883); RPL5 (0.882)
Homologues (species, bitscore): GART (Homo sapiens, 698.7); Gart (Mus musculus, 716.1); gart (Danio rerio, 681.0); gart (Xenopus tropicalis, 700.7); ade3 (Drosophila melanogaster, 538.9); F38B6.4 (Caenorhabditis elegans, 537.0); PUR2 (Arabidopsis thaliana, 339.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:58016-60424:+ | gene-YGL234W_AKU4011 | rna-NM_001181100.1_AKU4011 | cds-NP_011280.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000175.1:50050-52458:+ | gene-YGL234W_BG1 | rna-NM_001181100.1_BG1 | cds-NP_011280.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:58371-60779:+ | gene-YGL234W_Bruggeman | rna-NM_001181100.1_Bruggeman | cds-NP_011280.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:56437-58845:+ | gene-YGL234W_CAT1 | rna-NM_001181100.1_CAT1 | cds-NP_011280.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:62303-64711:+ | gene-YGL234W_CBS1585 | rna-NM_001181100.1_CBS1585 | cds-NP_011280.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:57023-59431:+ | gene-YGL234W_CBS436 | rna-NM_001181100.1_CBS436 | cds-NP_011280.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:49873-52281:+ | gene-YGL234W_CBS6412 | rna-NM_001181100.1_CBS6412 | cds-NP_011280.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:56163-58571:+ | gene-YGL234W_CBS6413 | rna-NM_001181100.1_CBS6413 | cds-NP_011280.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:56161-58569:+ | gene-YGL234W_CENPK1137D | rna-NM_001181100.1_CENPK1137D | cds-NP_011280.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:49103-51511:+ | gene-YGL234W_EthanolRed | rna-NM_001181100.1_EthanolRed | cds-NP_011280.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:49688-52096:+ | gene-YGL234W_FaliES1 | rna-NM_001181100.1_FaliES1 | cds-NP_011280.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000079.1:15028-17436:- | gene-YGL234W_JAY291 | rna-NM_001181100.1_JAY291 | cds-NP_011280.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:58298-60706:+ | gene-YGL234W_MUCL30387 | rna-NM_001181100.1_MUCL30387 | cds-NP_011280.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:60462-62870:+ | gene-YGL234W_MUCL30388 | rna-NM_001181100.1_MUCL30388 | cds-NP_011280.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:58900-61308:+ | gene-YGL234W_MUCL39482 | rna-NM_001181100.1_MUCL39482 | cds-NP_011280.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:61782-64190:+ | gene-YGL234W_MUCL42920 | rna-NM_001181100.1_MUCL42920 | cds-NP_011280.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:56482-58890:+ | gene-YGL234W_NCIM3186 | rna-NM_001181100.1_NCIM3186 | cds-NP_011280.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:50661-53069:+ | gene-YGL234W_NCYC1407 | rna-NM_001181100.1_NCYC1407 | cds-NP_011280.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:52518-54926:+ | gene-YGL234W_PE2H3 | rna-NM_001181100.1_PE2H3 | cds-NP_011280.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:52066-54474:+ | gene-YGL234W_PE2H4 | rna-NM_001181100.1_PE2H4 | cds-NP_011280.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:56482-58890:+ | gene-YGL234W_S288C | rna-NM_001181100.1_S288C | cds-NP_011280.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000002.1:316440-318848:- | gene-YGL234W_SA1 | rna-NM_001181100.1_SA1 | cds-NP_011280.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:49994-52402:+ | gene-YGL234W_ThermosaccDry | rna-NM_001181100.1_ThermosaccDry | cds-NP_011280.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:56952-59360:+ | gene-YGL234W_VR1 | rna-NM_001181100.1_VR1 | cds-NP_011280.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:49039-51447:+ | gene-YGL234W_ZTW1 | rna-NM_001181100.1_ZTW1 | cds-NP_011280.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:57672-60080:+ | gene-YGL234W_Sparadoxus | rna-NM_001181100.1_Sparadoxus | cds-NP_011280.1_Sparadoxus | 93.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |