Gene name: ADE4
Reference locus (S288C): YMR300C
Gene biotype: protein_coding
Description: Amidophosphoribosyltransferase; Phosphoribosylpyrophosphate amidotransferase (PRPPAT); catalyzes first step of the 'de novo' purine nucleotide biosynthetic pathway; also known as amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family
Top 10 interactors (score): ADE6 (0.999); ADE5,7 (0.999); ADE17 (0.998); ADE8 (0.998); ADE13 (0.997); URA2 (0.994); ADE1 (0.993); GLN1 (0.993); CPA2 (0.99); ADE16 (0.989); CPA1 (0.981); YMR084W (0.978); SHM2 (0.976); ADE2 (0.973); GLT1 (0.968); GFA1 (0.967); ADE12 (0.961); PRS2 (0.951); PRS1 (0.937); PRS4 (0.934)
Homologues (species, bitscore): PPAT (Homo sapiens, 235.7); Ppat (Mus musculus, 229.6); ppat (Danio rerio, 247.3); ppat (Xenopus tropicalis, 241.1); Prat2 (Drosophila melanogaster, 223.8); ppat-1 (Caenorhabditis elegans, 214.2); ASE2 (Arabidopsis thaliana, 259.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:904605-906137:- | gene-YMR300C_AKU4011 | rna-NM_001182809.1_AKU4011 | cds-NP_014029.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000069.1:47570-49102:+ | gene-YMR300C_BG1 | rna-NM_001182809.1_BG1 | cds-NP_014029.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:849815-851347:- | gene-YMR300C_Bruggeman | rna-NM_001182809.1_Bruggeman | cds-NP_014029.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:853097-854629:- | gene-YMR300C_CAT1 | rna-NM_001182809.1_CAT1 | cds-NP_014029.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:836856-838388:- | gene-YMR300C_CBS1585 | rna-NM_001182809.1_CBS1585 | cds-NP_014029.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:859171-860703:- | gene-YMR300C_CBS436 | rna-NM_001182809.1_CBS436 | cds-NP_014029.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:948431-949963:- | gene-YMR300C_CBS6412 | rna-NM_001182809.1_CBS6412 | cds-NP_014029.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:835975-837507:- | gene-YMR300C_CBS6413 | rna-NM_001182809.1_CBS6413 | cds-NP_014029.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:860093-861625:- | gene-YMR300C_CENPK1137D | rna-NM_001182809.1_CENPK1137D | cds-NP_014029.1_CENPK1137D | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:897294-898826:- | gene-YMR300C_EthanolRed | rna-NM_001182809.1_EthanolRed | cds-NP_014029.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:843321-844853:- | gene-YMR300C_FaliES1 | rna-NM_001182809.1_FaliES1 | cds-NP_014029.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000262.1:6878-8410:+ | gene-YMR300C_JAY291 | rna-NM_001182809.1_JAY291 | cds-NP_014029.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:843642-845174:- | gene-YMR300C_MUCL30387 | rna-NM_001182809.1_MUCL30387 | cds-NP_014029.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:853033-854565:- | gene-YMR300C_MUCL30388 | rna-NM_001182809.1_MUCL30388 | cds-NP_014029.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:837921-839453:- | gene-YMR300C_MUCL39482 | rna-NM_001182809.1_MUCL39482 | cds-NP_014029.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:846748-848280:- | gene-YMR300C_MUCL42920 | rna-NM_001182809.1_MUCL42920 | cds-NP_014029.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:865513-867045:- | gene-YMR300C_NCIM3186 | rna-NM_001182809.1_NCIM3186 | cds-NP_014029.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:837575-839107:- | gene-YMR300C_NCYC1407 | rna-NM_001182809.1_NCYC1407 | cds-NP_014029.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:853393-854925:- | gene-YMR300C_PE2H3 | rna-NM_001182809.1_PE2H3 | cds-NP_014029.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:849368-850900:- | gene-YMR300C_PE2H4 | rna-NM_001182809.1_PE2H4 | cds-NP_014029.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:865559-867091:- | gene-YMR300C_S288C | rna-NM_001182809.1_S288C | cds-NP_014029.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000036.1:43351-44883:- | gene-YMR300C_SA1 | rna-NM_001182809.1_SA1 | cds-NP_014029.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:839489-841021:- | gene-YMR300C_ThermosaccDry | rna-NM_001182809.1_ThermosaccDry | cds-NP_014029.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:853246-854778:- | gene-YMR300C_VR1 | rna-NM_001182809.1_VR1 | cds-NP_014029.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000028.1:254727-256259:- | gene-YMR300C_ZTW1 | rna-NM_001182809.1_ZTW1 | cds-NP_014029.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:858126-859658:- | gene-YMR300C_Sparadoxus | rna-NM_001182809.1_Sparadoxus | cds-NP_014029.1_Sparadoxus | 93.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |