Gene name: ADE17
Reference locus (S288C): YMR120C
Gene biotype: protein_coding
Description: Bifunctional purine biosynthesis protein ADE17; Enzyme of 'de novo' purine biosynthesis; contains both 5-aminoimidazole-4-carboxamide ribonucleotide transformylase and inosine monophosphate cyclohydrolase activities; ADE17 has a paralog, ADE16, that arose from the whole genome duplication; ade16 ade17 mutants require adenine and histidine; Belongs to the PurH family
Top 10 interactors (score): ADE8 (0.999); ADE13 (0.999); SHM2 (0.999); ADE16 (0.999); ADE4 (0.998); ADE1 (0.998); ADE12 (0.997); ADE5,7 (0.997); GCV1 (0.994); ADE6 (0.992); ADE3 (0.987); SHM1 (0.982); HPT1 (0.98); MTD1 (0.98); MIS1 (0.971); IMD3 (0.969); APT2 (0.966); APT1 (0.966); ADE2 (0.963); DFR1 (0.959)
Homologues (species, bitscore): ATIC (Homo sapiens, 746.5); Atic (Mus musculus, 738.0); atic (Danio rerio, 734.6); atic (Xenopus tropicalis, 728.8); BEST:GH11240 (Drosophila melanogaster, 746.1); C55F2.1 (Caenorhabditis elegans, 690.3); AT2G35040 (Arabidopsis thaliana, 243.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:546880-548658:- | gene-YMR120C_AKU4011 | rna-NM_001182621.1_AKU4011 | cds-NP_013839.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000068.1:123881-125659:+ | gene-YMR120C_BG1 | rna-NM_001182621.1_BG1 | cds-NP_013839.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:489802-491580:- | gene-YMR120C_Bruggeman | rna-NM_001182621.1_Bruggeman | cds-NP_013839.1_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:491473-493251:- | gene-YMR120C_CAT1 | rna-NM_001182621.1_CAT1 | cds-NP_013839.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:479803-481581:- | gene-YMR120C_CBS1585 | rna-NM_001182621.1_CBS1585 | cds-NP_013839.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:483665-485443:- | gene-YMR120C_CBS436 | rna-NM_001182621.1_CBS436 | cds-NP_013839.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:592796-594574:- | gene-YMR120C_CBS6412 | rna-NM_001182621.1_CBS6412 | cds-NP_013839.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:478363-480141:- | gene-YMR120C_CBS6413 | rna-NM_001182621.1_CBS6413 | cds-NP_013839.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:502030-503808:- | gene-YMR120C_CENPK1137D | rna-NM_001182621.1_CENPK1137D | cds-NP_013839.1_CENPK1137D | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005483.1:478121-479899:- | gene-YMR120C_EthanolRed | rna-NM_001182621.1_EthanolRed | cds-NP_013839.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:484035-485813:- | gene-YMR120C_FaliES1 | rna-NM_001182621.1_FaliES1 | cds-NP_013839.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000294.1:41285-43063:+ | gene-YMR120C_JAY291 | rna-NM_001182621.1_JAY291 | cds-NP_013839.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:484781-486559:- | gene-YMR120C_MUCL30387 | rna-NM_001182621.1_MUCL30387 | cds-NP_013839.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:489897-491675:- | gene-YMR120C_MUCL30388 | rna-NM_001182621.1_MUCL30388 | cds-NP_013839.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:480504-482282:- | gene-YMR120C_MUCL39482 | rna-NM_001182621.1_MUCL39482 | cds-NP_013839.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:486917-488695:- | gene-YMR120C_MUCL42920 | rna-NM_001182621.1_MUCL42920 | cds-NP_013839.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:507456-509234:- | gene-YMR120C_NCIM3186 | rna-NM_001182621.1_NCIM3186 | cds-NP_013839.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:480142-481920:- | gene-YMR120C_NCYC1407 | rna-NM_001182621.1_NCYC1407 | cds-NP_013839.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:490572-492350:- | gene-YMR120C_PE2H3 | rna-NM_001182621.1_PE2H3 | cds-NP_013839.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:491026-492804:- | gene-YMR120C_PE2H4 | rna-NM_001182621.1_PE2H4 | cds-NP_013839.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:507502-509280:- | gene-YMR120C_S288C | rna-NM_001182621.1_S288C | cds-NP_013839.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000048.1:61982-63760:+ | gene-YMR120C_SA1 | rna-NM_001182621.1_SA1 | cds-NP_013839.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:480519-482297:- | gene-YMR120C_ThermosaccDry | rna-NM_001182621.1_ThermosaccDry | cds-NP_013839.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:492521-494299:- | gene-YMR120C_VR1 | rna-NM_001182621.1_VR1 | cds-NP_013839.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000027.1:455525-457303:- | gene-YMR120C_ZTW1 | rna-NM_001182621.1_ZTW1 | cds-NP_013839.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:491783-493561:- | gene-YMR120C_Sparadoxus | rna-NM_001182621.1_Sparadoxus | cds-NP_013839.1_Sparadoxus | 92.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |