Gene name: ADE16
Reference locus (S288C): YLR028C
Gene biotype: protein_coding
Description: Bifunctional purine biosynthesis protein ADE16; Enzyme of 'de novo' purine biosynthesis; contains both 5-aminoimidazole-4-carboxamide ribonucleotide transformylase and inosine monophosphate cyclohydrolase activities; ADE16 has a paralog, ADE17, that arose from the whole genome duplication; ade16 ade17 mutants require adenine and histidine; Belongs to the PurH family
Top 10 interactors (score): ADE17 (0.999); ADE13 (0.999); ADE8 (0.999); ADE5,7 (0.994); ADE12 (0.994); SHM2 (0.992); ADE6 (0.989); ADE4 (0.989); ADE1 (0.988); ADE3 (0.988); SHM1 (0.982); GCV1 (0.979); MIS1 (0.971); IMD3 (0.969); HPT1 (0.968); APT2 (0.966); APT1 (0.966); HAM1 (0.961); AMD1 (0.959); DFR1 (0.958)
Homologues (species, bitscore): ATIC (Homo sapiens, 741.9); Atic (Mus musculus, 740.0); atic (Danio rerio, 747.7); atic (Xenopus tropicalis, 731.1); BEST:GH11240 (Drosophila melanogaster, 737.3); C55F2.1 (Caenorhabditis elegans, 676.0); AT2G35040 (Arabidopsis thaliana, 248.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:187472-189247:- | gene-YLR028C_AKU4011 | rna-NM_001181915.1_AKU4011 | cds-NP_013128.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000212.1:150746-152521:- | gene-YLR028C_BG1 | rna-NM_001181915.1_BG1 | cds-NP_013128.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:197864-199639:- | gene-YLR028C_Bruggeman | rna-NM_001181915.1_Bruggeman | cds-NP_013128.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:198190-199965:- | gene-YLR028C_CAT1 | rna-NM_001181915.1_CAT1 | cds-NP_013128.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:195098-196873:- | gene-YLR028C_CBS1585 | rna-NM_001181915.1_CBS1585 | cds-NP_013128.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:185730-187505:- | gene-YLR028C_CBS436 | rna-NM_001181915.1_CBS436 | cds-NP_013128.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:193508-195283:- | gene-YLR028C_CBS6412 | rna-NM_001181915.1_CBS6412 | cds-NP_013128.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:195360-197135:- | gene-YLR028C_CBS6413 | rna-NM_001181915.1_CBS6413 | cds-NP_013128.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:184781-186556:- | gene-YLR028C_CENPK1137D | rna-NM_001181915.1_CENPK1137D | cds-NP_013128.1_CENPK1137D | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:187483-189258:- | gene-YLR028C_EthanolRed | rna-NM_001181915.1_EthanolRed | cds-NP_013128.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:187393-189168:- | gene-YLR028C_FaliES1 | rna-NM_001181915.1_FaliES1 | cds-NP_013128.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000431.1:31246-33021:- | gene-YLR028C_JAY291 | rna-NM_001181915.1_JAY291 | cds-NP_013128.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:195218-196993:- | gene-YLR028C_MUCL30387 | rna-NM_001181915.1_MUCL30387 | cds-NP_013128.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:201841-203616:- | gene-YLR028C_MUCL30388 | rna-NM_001181915.1_MUCL30388 | cds-NP_013128.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:195593-197368:- | gene-YLR028C_MUCL39482 | rna-NM_001181915.1_MUCL39482 | cds-NP_013128.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:195494-197269:- | gene-YLR028C_MUCL42920 | rna-NM_001181915.1_MUCL42920 | cds-NP_013128.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:199514-201289:- | gene-YLR028C_NCIM3186 | rna-NM_001181915.1_NCIM3186 | cds-NP_013128.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:187651-189426:- | gene-YLR028C_NCYC1407 | rna-NM_001181915.1_NCYC1407 | cds-NP_013128.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:193529-195304:- | gene-YLR028C_PE2H3 | rna-NM_001181915.1_PE2H3 | cds-NP_013128.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:193270-195045:- | gene-YLR028C_PE2H4 | rna-NM_001181915.1_PE2H4 | cds-NP_013128.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:199540-201315:- | gene-YLR028C_S288C | rna-NM_001181915.1_S288C | cds-NP_013128.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000046.1:31383-33158:- | gene-YLR028C_SA1 | rna-NM_001181915.1_SA1 | cds-NP_013128.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:187559-189334:- | gene-YLR028C_ThermosaccDry | rna-NM_001181915.1_ThermosaccDry | cds-NP_013128.1_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:200978-202753:- | gene-YLR028C_VR1 | rna-NM_001181915.1_VR1 | cds-NP_013128.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000023.1:186921-188696:- | gene-YLR028C_ZTW1 | rna-NM_001181915.1_ZTW1 | cds-NP_013128.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:195701-197476:- | gene-YLR028C_Sparadoxus | rna-NM_001181915.1_Sparadoxus | cds-NP_013128.1_Sparadoxus | 91.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |