Gene name: ADE13
Reference locus (S288C): YLR359W
Gene biotype: protein_coding
Description: Adenylosuccinate lyase; catalyzes two steps in the 'de novo' purine nucleotide biosynthetic pathway; expression is repressed by adenine and activated by Bas1p and Pho2p; mutations in human ortholog ADSL cause adenylosuccinase deficiency; human ADSL can complement yeast ADE13 null mutant
Top 10 interactors (score): ADE16 (0.999); ADE17 (0.999); ADE12 (0.999); ADE1 (0.999); ADE4 (0.997); AMD1 (0.996); ADE5,7 (0.996); ADO1 (0.988); APT2 (0.987); GUA1 (0.987); APT1 (0.987); SHM2 (0.981); ADK1 (0.975); ADE8 (0.972); MTD1 (0.971); ADE6 (0.967); ARG4 (0.966); BAS1 (0.935); ADE2 (0.934); ADK2 (0.933)
Homologues (species, bitscore): ADSL (Homo sapiens, 629.0); Adsl (Mus musculus, 632.1); adsl (Danio rerio, 652.5); adsl (Xenopus tropicalis, 628.6); AdSL (Drosophila melanogaster, 585.9); R06C7.5 (Caenorhabditis elegans, 382.1); AT1G36280 (Arabidopsis thaliana, 55.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:793827-795275:+ | gene-YLR359W_AKU4011 | rna-NM_001182248.1_AKU4011 | cds-NP_013463.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000048.1:25953-27401:+ | gene-YLR359W_BG1 | rna-NM_001182248.1_BG1 | cds-NP_013463.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:832125-833573:+ | gene-YLR359W_Bruggeman | rna-NM_001182248.1_Bruggeman | cds-NP_013463.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:827629-829077:+ | gene-YLR359W_CAT1 | rna-NM_001182248.1_CAT1 | cds-NP_013463.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:828819-830267:+ | gene-YLR359W_CBS1585 | rna-NM_001182248.1_CBS1585 | cds-NP_013463.1_CBS1585 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:813034-814482:+ | gene-YLR359W_CBS436 | rna-NM_001182248.1_CBS436 | cds-NP_013463.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:865826-867274:+ | gene-YLR359W_CBS6412 | rna-NM_001182248.1_CBS6412 | cds-NP_013463.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:829710-831158:+ | gene-YLR359W_CBS6413 | rna-NM_001182248.1_CBS6413 | cds-NP_013463.1_CBS6413 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:828983-830431:+ | gene-YLR359W_CENPK1137D | rna-NM_001182248.1_CENPK1137D | cds-NP_013463.1_CENPK1137D | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:786389-787837:+ | gene-YLR359W_EthanolRed | rna-NM_001182248.1_EthanolRed | cds-NP_013463.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:815194-816642:+ | gene-YLR359W_FaliES1 | rna-NM_001182248.1_FaliES1 | cds-NP_013463.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000161.1:25770-27218:+ | gene-YLR359W_JAY291 | rna-NM_001182248.1_JAY291 | cds-NP_013463.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:829540-830988:+ | gene-YLR359W_MUCL30387 | rna-NM_001182248.1_MUCL30387 | cds-NP_013463.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:835158-836606:+ | gene-YLR359W_MUCL30388 | rna-NM_001182248.1_MUCL30388 | cds-NP_013463.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:830038-831486:+ | gene-YLR359W_MUCL39482 | rna-NM_001182248.1_MUCL39482 | cds-NP_013463.1_MUCL39482 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:825316-826764:+ | gene-YLR359W_MUCL42920 | rna-NM_001182248.1_MUCL42920 | cds-NP_013463.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:844256-845704:+ | gene-YLR359W_NCIM3186 | rna-NM_001182248.1_NCIM3186 | cds-NP_013463.1_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:839258-840706:+ | gene-YLR359W_NCYC1407 | rna-NM_001182248.1_NCYC1407 | cds-NP_013463.1_NCYC1407 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:826191-827639:+ | gene-YLR359W_PE2H3 | rna-NM_001182248.1_PE2H3 | cds-NP_013463.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:825935-827383:+ | gene-YLR359W_PE2H4 | rna-NM_001182248.1_PE2H4 | cds-NP_013463.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:844282-845730:+ | gene-YLR359W_S288C | rna-NM_001182248.1_S288C | cds-NP_013463.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000007.1:202977-204425:- | gene-YLR359W_SA1 | rna-NM_001182248.1_SA1 | cds-NP_013463.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:818032-819480:+ | gene-YLR359W_ThermosaccDry | rna-NM_001182248.1_ThermosaccDry | cds-NP_013463.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:831298-832746:+ | gene-YLR359W_VR1 | rna-NM_001182248.1_VR1 | cds-NP_013463.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000025.1:155474-156922:+ | gene-YLR359W_ZTW1 | rna-NM_001182248.1_ZTW1 | cds-NP_013463.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:804098-805546:+ | gene-YLR359W_Sparadoxus | rna-NM_001182248.1_Sparadoxus | cds-NP_013463.1_Sparadoxus | 91.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |