Gene name: ADE12
Reference locus (S288C): YNL220W
Gene biotype: protein_coding
Description: Adenylosuccinate synthase; catalyzes the first step in synthesis of adenosine monophosphate from inosine 5'monophosphate during purine nucleotide biosynthesis; exhibits binding to single-stranded autonomously replicating (ARS) core sequence
Top 10 interactors (score): ADE13 (0.999); ADE17 (0.997); HAM1 (0.996); ADO1 (0.996); ADE16 (0.994); URA2 (0.992); HPT1 (0.992); AMD1 (0.991); IMD3 (0.989); IMD2 (0.988); GUA1 (0.982); PRM15 (0.979); IMD4 (0.976); YJL068C (0.975); SAH1 (0.969); ARG1 (0.968); RKI1 (0.963); ADH4 (0.962); COF1 (0.962); APE4 (0.962)
Homologues (species, bitscore): ADSS (Homo sapiens, 502.3); Adss (Mus musculus, 505.0); adssl1 (Danio rerio, 511.1); adssl1 (Xenopus tropicalis, 515.4); AdSS (Drosophila melanogaster, 494.6); C37H5.6 (Caenorhabditis elegans, 456.4); ADSS (Arabidopsis thaliana, 438.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:228194-229495:+ | gene-YNL220W_AKU4011 | rna-NM_001183058.1_AKU4011 | cds-NP_014179.1_AKU4011 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:132137-133438:+ | gene-YNL220W_BG1 | rna-NM_001183058.1_BG1 | cds-NP_014179.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:238238-239539:+ | gene-YNL220W_Bruggeman | rna-NM_001183058.1_Bruggeman | cds-NP_014179.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:245391-246692:+ | gene-YNL220W_CAT1 | rna-NM_001183058.1_CAT1 | cds-NP_014179.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:228589-229890:+ | gene-YNL220W_CBS1585 | rna-NM_001183058.1_CBS1585 | cds-NP_014179.1_CBS1585 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:223669-224970:+ | gene-YNL220W_CBS436 | rna-NM_001183058.1_CBS436 | cds-NP_014179.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:224627-225928:+ | gene-YNL220W_CBS6412 | rna-NM_001183058.1_CBS6412 | cds-NP_014179.1_CBS6412 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:225273-226574:+ | gene-YNL220W_CBS6413 | rna-NM_001183058.1_CBS6413 | cds-NP_014179.1_CBS6413 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:228215-229516:+ | gene-YNL220W_CENPK1137D | rna-NM_001183058.1_CENPK1137D | cds-NP_014179.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:225828-227129:+ | gene-YNL220W_EthanolRed | rna-NM_001183058.1_EthanolRed | cds-NP_014179.1_EthanolRed | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:220570-221871:+ | gene-YNL220W_FaliES1 | rna-NM_001183058.1_FaliES1 | cds-NP_014179.1_FaliES1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000082.1:131730-133031:+ | gene-YNL220W_JAY291 | rna-NM_001183058.1_JAY291 | cds-NP_014179.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:233774-235075:+ | gene-YNL220W_MUCL30387 | rna-NM_001183058.1_MUCL30387 | cds-NP_014179.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:232355-233656:+ | gene-YNL220W_MUCL30388 | rna-NM_001183058.1_MUCL30388 | cds-NP_014179.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:226079-227380:+ | gene-YNL220W_MUCL39482 | rna-NM_001183058.1_MUCL39482 | cds-NP_014179.1_MUCL39482 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:228335-229636:+ | gene-YNL220W_MUCL42920 | rna-NM_001183058.1_MUCL42920 | cds-NP_014179.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:234382-235683:+ | gene-YNL220W_NCIM3186 | rna-NM_001183058.1_NCIM3186 | cds-NP_014179.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:228169-229470:+ | gene-YNL220W_NCYC1407 | rna-NM_001183058.1_NCYC1407 | cds-NP_014179.1_NCYC1407 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:225075-226376:+ | gene-YNL220W_PE2H3 | rna-NM_001183058.1_PE2H3 | cds-NP_014179.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:224463-225764:+ | gene-YNL220W_PE2H4 | rna-NM_001183058.1_PE2H4 | cds-NP_014179.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:234413-235714:+ | gene-YNL220W_S288C | rna-NM_001183058.1_S288C | cds-NP_014179.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000040.1:16596-17897:- | gene-YNL220W_SA1 | rna-NM_001183058.1_SA1 | cds-NP_014179.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:221426-222727:+ | gene-YNL220W_ThermosaccDry | rna-NM_001183058.1_ThermosaccDry | cds-NP_014179.1_ThermosaccDry | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:240431-241732:+ | gene-YNL220W_VR1 | rna-NM_001183058.1_VR1 | cds-NP_014179.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:131758-133059:+ | gene-YNL220W_ZTW1 | rna-NM_001183058.1_ZTW1 | cds-NP_014179.1_ZTW1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:231841-233142:+ | gene-YNL220W_Sparadoxus | rna-NM_001183058.1_Sparadoxus | cds-NP_014179.1_Sparadoxus | 93.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |