Gene name: ADE1
Reference locus (S288C): YAR015W
Gene biotype: protein_coding
Description: Phosphoribosylaminoimidazole-succinocarboxamide synthase; N-succinyl-5-aminoimidazole-4-carboxamide ribotide synthetase; required for 'de novo' purine nucleotide biosynthesis; red pigment accumulates in mutant cells deprived of adenine; protein abundance increases in response to DNA replication stress
Top 10 interactors (score): ADE5,7 (0.999); ADE13 (0.999); ADE17 (0.998); ADE2 (0.996); ADE8 (0.995); ADE4 (0.993); ADE6 (0.99); ADE16 (0.988); URA3 (0.978); SHM2 (0.975); ADE3 (0.972); NIT2 (0.964); SUP35 (0.961); GUA1 (0.952); ADE12 (0.939); SFB3 (0.926); SHM1 (0.919); HIS4 (0.916); LEU2 (0.912); TRP1 (0.909)
Homologues (species, bitscore): PAICS (Homo sapiens, 55.1); paics (Danio rerio, 55.1); paics.1 (Xenopus tropicalis, 54.7); PUR7 (Arabidopsis thaliana, 139.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005295.1:148874-149794:+ | gene-YAR015W_AKU4011 | rna-NM_001178216.1_AKU4011 | cds-NP_009409.1_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000193.1:3535-4455:+ | gene-YAR015W_BG1 | rna-NM_001178216.1_BG1 | cds-NP_009409.1_BG1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005503.1:164889-165809:+ | gene-YAR015W_Bruggeman | rna-NM_001178216.1_Bruggeman | cds-NP_009409.1_Bruggeman | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005519.1:150512-151432:+ | gene-YAR015W_CAT1 | rna-NM_001178216.1_CAT1 | cds-NP_009409.1_CAT1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005359.1:161572-162492:+ | gene-YAR015W_CBS1585 | rna-NM_001178216.1_CBS1585 | cds-NP_009409.1_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005343.1:161898-162818:+ | gene-YAR015W_CBS436 | rna-NM_001178216.1_CBS436 | cds-NP_009409.1_CBS436 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:774314-775234:+ | gene-YAR015W_CBS6412 | rna-NM_001178216.1_CBS6412 | cds-NP_009409.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005311.1:159838-160758:+ | gene-YAR015W_CBS6413 | rna-NM_001178216.1_CBS6413 | cds-NP_009409.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001522.1:163351-164271:+ | gene-YAR015W_CENPK1137D | rna-NM_001178216.1_CENPK1137D | cds-NP_009409.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005471.1:149428-150348:+ | gene-YAR015W_EthanolRed | rna-NM_001178216.1_EthanolRed | cds-NP_009409.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005535.1:165089-166009:+ | gene-YAR015W_FaliES1 | rna-NM_001178216.1_FaliES1 | cds-NP_009409.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000304.1:3226-4146:+ | gene-YAR015W_JAY291 | rna-NM_001178216.1_JAY291 | cds-NP_009409.1_JAY291 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005407.1:165425-166345:+ | gene-YAR015W_MUCL30387 | rna-NM_001178216.1_MUCL30387 | cds-NP_009409.1_MUCL30387 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005439.1:162079-162999:+ | gene-YAR015W_MUCL30388 | rna-NM_001178216.1_MUCL30388 | cds-NP_009409.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005279.1:160826-161746:+ | gene-YAR015W_MUCL39482 | rna-NM_001178216.1_MUCL39482 | cds-NP_009409.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005423.1:163227-164147:+ | gene-YAR015W_MUCL42920 | rna-NM_001178216.1_MUCL42920 | cds-NP_009409.1_MUCL42920 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011810.1:169252-170172:+ | gene-YAR015W_NCIM3186 | rna-NM_001178216.1_NCIM3186 | cds-NP_009409.1_NCIM3186 | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005263.1:148238-149158:+ | gene-YAR015W_NCYC1407 | rna-NM_001178216.1_NCYC1407 | cds-NP_009409.1_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994140.1:156427-157347:+ | gene-YAR015W_PE2H3 | rna-NM_001178216.1_PE2H3 | cds-NP_009409.1_PE2H3 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999872.1:156146-157066:+ | gene-YAR015W_PE2H4 | rna-NM_001178216.1_PE2H4 | cds-NP_009409.1_PE2H4 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001133.9:169375-170295:+ | gene-YAR015W_S288C | rna-NM_001178216.1_S288C | cds-NP_009409.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000100.1:22177-23097:+ | gene-YAR015W_SA1 | rna-NM_001178216.1_SA1 | cds-NP_009409.1_SA1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005487.1:164094-165014:+ | gene-YAR015W_ThermosaccDry | rna-NM_001178216.1_ThermosaccDry | cds-NP_009409.1_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005455.1:168650-169570:+ | gene-YAR015W_VR1 | rna-NM_001178216.1_VR1 | cds-NP_009409.1_VR1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000002.1:135917-136837:+ | gene-YAR015W_ZTW1 | rna-NM_001178216.1_ZTW1 | cds-NP_009409.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047487.1:153580-154500:+ | gene-YAR015W_Sparadoxus | rna-NM_001178216.1_Sparadoxus | cds-NP_009409.1_Sparadoxus | 94.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |