ADD66 (YKL206C)


Gene profile

Gene name: ADD66
Reference locus (S288C): YKL206C
Gene biotype: protein_coding

Description: Protein involved in 20S proteasome assembly; forms a heterodimer with Pba1p that binds to proteasome precursors; interaction with Pba1p-Add66p may affect function of the mature proteasome and its role in maintaining respiratory metabolism; similar to human PAC2 constituent of the PAC1-PAC2 complex involved in proteasome assembly

Top 10 interactors (score): PBA1 (0.999); PUP2 (0.999); UMP1 (0.999); PRE5 (0.999); PRE4 (0.997); PRE7 (0.988); PRE1 (0.987); PRE9 (0.987); PUP1 (0.984); PRE8 (0.951); PUP3 (0.945); IRC25 (0.945); POC4 (0.943); PRE6 (0.939); PRE3 (0.916); PRE2 (0.915); PRE10 (0.913); SCL1 (0.909); BLM10 (0.886); RPT5 (0.841)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005305.1:35320-36123:- gene-YKL206C_AKU4011 rna-NM_001179771.1_AKU4011 cds-NP_012716.1_AKU4011 99.8 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000030.1:12404-13207:- gene-YKL206C_BG1 rna-NM_001179771.1_BG1 cds-NP_012716.1_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005513.1:52992-53795:- gene-YKL206C_Bruggeman rna-NM_001179771.1_Bruggeman cds-NP_012716.1_Bruggeman 99.8 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005529.1:48183-48986:- gene-YKL206C_CAT1 rna-NM_001179771.1_CAT1 cds-NP_012716.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005369.1:47332-48135:- gene-YKL206C_CBS1585 rna-NM_001179771.1_CBS1585 cds-NP_012716.1_CBS1585 99.8 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005353.1:46533-47336:- gene-YKL206C_CBS436 rna-NM_001179771.1_CBS436 cds-NP_012716.1_CBS436 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005337.1:32589-33392:- gene-YKL206C_CBS6412 rna-NM_001179771.1_CBS6412 cds-NP_012716.1_CBS6412 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005321.1:47969-48772:- gene-YKL206C_CBS6413 rna-NM_001179771.1_CBS6413 cds-NP_012716.1_CBS6413 99.8 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001532.1:48788-49591:- gene-YKL206C_CENPK1137D rna-NM_001179771.1_CENPK1137D cds-NP_012716.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005481.1:46803-47606:- gene-YKL206C_EthanolRed rna-NM_001179771.1_EthanolRed cds-NP_012716.1_EthanolRed 99.7 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005545.1:46862-47665:- gene-YKL206C_FaliES1 rna-NM_001179771.1_FaliES1 cds-NP_012716.1_FaliES1 99.7 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000006.2:46476-47279:- gene-YKL206C_JAY291 rna-NM_001179771.1_JAY291 cds-NP_012716.1_JAY291 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005417.1:55527-56330:- gene-YKL206C_MUCL30387 rna-NM_001179771.1_MUCL30387 cds-NP_012716.1_MUCL30387 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005449.1:49615-50418:- gene-YKL206C_MUCL30388 rna-NM_001179771.1_MUCL30388 cds-NP_012716.1_MUCL30388 99.8 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005289.1:47389-48192:- gene-YKL206C_MUCL39482 rna-NM_001179771.1_MUCL39482 cds-NP_012716.1_MUCL39482 99.8 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005433.1:50683-51486:- gene-YKL206C_MUCL42920 rna-NM_001179771.1_MUCL42920 cds-NP_012716.1_MUCL42920 99.8 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011820.1:48995-49798:- gene-YKL206C_NCIM3186 rna-NM_001179771.1_NCIM3186 cds-NP_012716.1_NCIM3186 99.7 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005273.1:47413-48216:- gene-YKL206C_NCYC1407 rna-NM_001179771.1_NCYC1407 cds-NP_012716.1_NCYC1407 99.8 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994150.1:55111-55914:- gene-YKL206C_PE2H3 rna-NM_001179771.1_PE2H3 cds-NP_012716.1_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999882.1:51309-52112:- gene-YKL206C_PE2H4 rna-NM_001179771.1_PE2H4 cds-NP_012716.1_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001143.9:49006-49809:- gene-YKL206C_S288C rna-NM_001179771.1_S288C cds-NP_012716.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000092.1:18064-18867:+ gene-YKL206C_SA1 rna-NM_001179771.1_SA1 cds-NP_012716.1_SA1 99.8 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005497.1:47610-48413:- gene-YKL206C_ThermosaccDry rna-NM_001179771.1_ThermosaccDry cds-NP_012716.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005465.1:46715-47518:- gene-YKL206C_VR1 rna-NM_001179771.1_VR1 cds-NP_012716.1_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000022.1:46524-47327:- gene-YKL206C_ZTW1 rna-NM_001179771.1_ZTW1 cds-NP_012716.1_ZTW1 99.8 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047497.1:55270-56073:- gene-YKL206C_Sparadoxus rna-NM_001179771.1_Sparadoxus cds-NP_012716.1_Sparadoxus 90.7 100.0 Verified 1 1 1 False True False False False

Additional files